Results 41 to 50 of about 27,539 (254)
Evolving Bacterial Envelopes and Plasticity of TLR2-Dependent Responses: Basic Research and Translational Opportunities. [PDF]
, 2013 Innate immune mechanisms that follow early recognition of microbes influence the nature and magnitude of subsequent adaptive immune responses. Early detection of microbes depends on pattern recognition receptors that sense pathogen-associated molecular ...
Lee, Dennis Sang Won +2 more
core +6 more sources
Spirochetal Lipoproteins and Immune Evasion. [PDF]
, 2017 Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani +2 more
core +1 more source
Viruses, 2020 The highly conserved extracellular domain of the transmembrane protein M2 (M2e) of the influenza A virus is a promising target for the development of broad-spectrum vaccines. However, M2e is a poor immunogen by itself and must be linked to an appropriate
Anna A. Zykova +6 more
doaj +1 more source
A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]
, 2010 Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J. +9 more
core +2 more sources
Frontiers in Microbiology, 2017 Antibiotic resistance has become one of the world’s most severe problems because of the overuse of antibiotics. Antibiotic-resistant bacteria are more difficult to kill and more expensive to treat. Researchers have been studied on antibiotic alternatives
Yulin Chen +6 more
doaj +1 more source
MICROBIAL SURFACTANTS. II. LIPOPEPTIDES [PDF]
Biotechnologia Acta, 2014 The classification and the chemical structure of the lipopeptides and their producers (bacteria of the genera Bacillus and Pseudomonas) are given.
T. P. Pirog +2 more
doaj +1 more source
Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine [PDF]
, 2020 The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites.
Amoozegar, Mohammad Ali +2 more
core +1 more source
Angewandte Chemie, EarlyView.The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...
Luca De Simone Carone +17 more
wiley +2 more sources
The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation. [PDF]
PLoS ONE, 2010 Natural killer (NK) cells are lymphocyte effectors that are activated to control certain microbial infections and tumors. Many NK-activating and regulating receptors are involved in regulating NK cell function.
Masahiro Azuma +9 more
doaj +1 more source
Lipopeptide overproduction by cell immobilization on iron-enriched light polymer particles [PDF]
, 2009 The study concerns surfactin and/or fengycin batch production by immobilized cells of Bacillus subtilis ATCC 21332. Light carriers designed for a three phase inverse fluidized bed biofilm reactor (TPFIBR) were used.
Gancel, Frédérique +4 more
core +1 more source