Results 71 to 80 of about 7,978 (212)

Lipoxin A4 Activates Alveolar Epithelial Sodium Channel, Na,K-ATPase, and Increases Alveolar Fluid Clearance

, 2013
Edema fluid resorption is critical for gas exchange, and both alveolar epithelial sodium channel (ENaC) and Na,K-ATPase are accredited with key roles in the resolution of pulmonary edema.
Ying, Bin-Yu, Ru Li, Wu, De-Rong, Zheng, Xia, Jin, Sheng-Wei, Bin-Yu Ying, Chang-Jiang Huang, He, Qian, Huang, Chang-Jiang, Qian Wang, Fang Chen, De-Rong Wu, Sheng-Xing Zheng, Zheng, Sheng-Xing, Qing-Quan Lian, Lian, Qing-Quan, Smith, Fang Gao; id_orcid, Chen, Fang, Yi Yang, Qian He, Li, Ru, Wang, Qian, Sheng-Wei Jin, Xia Zheng, Fang Gao Smith, Yang, Yi   +25 more
core   +1 more source

Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice.

PLoS ONE, 2014
When 5-lipoxygenase (5-LO) is inhibited, roughly half of the CNS effect of the prototypic endocannabinoid anandamide (AEA) is lost. Therefore, we decided to investigate whether inhibiting this enzyme would influence physiological functions classically ...
Luciana M Leo, Suellen Almeida-Corrêa, Claudio A Canetti, Olavo B Amaral, Fernando A Bozza, Fabricio A Pamplona   +5 more
doaj   +1 more source

Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines

Journal of Neuroinflammation, 2012
Background The neuroinflammatory responses in the spinal cord following bone cancer development have been shown to play an important role in cancer-induced bone pain (CIBP).
Hu Shan, Mao-Ying Qi-Liang, Wang Jun, Wang Zhi-Fu, Mi Wen-Li, Wang Xiao-Wei, Jiang Jian-Wei, Huang Ya-Lin, Wu Gen-Cheng, Wang Yan-Qing   +9 more
doaj   +1 more source

In Vitro Anti‐Inflammatory Activity of Sour Cherry (Prunus cerasus L.) Seed Oil and Computational Safety Profiling

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
In vitro anti‐inflammatory activity of sour cherry (Prunus cerasus L.) seed oil and computational safety profiling. ABSTRACT This study aimed to evaluate the in vitro anti‐inflammatory activity of sour cherry seed oils, including samples obtained by Soxhlet extraction and maceration, as well as ten commercial samples.
Tuğba Aydin, Tuğba Günbatan, Aysel Berkkan, Onur Kenan Ulutaş, Melike Sucu   +4 more
wiley   +1 more source

A role for lipoxin A4 as anti-inflammatory and proresolution mediator in human parturition

, 2010
The purpose of this study was to investigate the role of lipoxin A(4), an anti-inflammatory and proresolution modulator, during human parturition. We measured serum levels of lipoxin A(4) and myometrial protein release using ELISA, quantified lipoxin ...
Norman, Jane E., Denison, Fiona C., Maldonado-Perez, David, David Maldonado‐Pérez, Jane E. Norman, Ellen Golightly, Golightly, Ellen, Jabbour, Henry N., Fiona C. Denison, Henry N. Jabbour   +9 more
core   +1 more source

Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis [PDF]

, 1995
Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. Polymorphonuclear neutrophils are important effectors of injury in host defense and inflammation.
Phillips, M. Laurie, Rennke, Helmut G., Brady, Hugh R., Papayianni, Aikaterina, Serhan, Charles N.   +4 more
core   +1 more source

Inflammation and pro-resolution inflammation after hepatobiliary surgery

World Journal of Surgical Oncology, 2017
Background The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics
Juan P. Cata, Jose F. Velasquez, Maria F. Ramirez, Jean-Nicolas Vauthey, Vijaya Gottumukkala, Claudius Conrad, Bradford J. Kim, Thomas Aloia   +7 more
doaj   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease of unknown cause, marked by excessive deposition of extracellular matrix (ECM) components such as collagen. This pathological accumulation results in progressive destruction of the lung architecture and ultimately leads to respiratory failure.
Yining Zhang, Ling Teng, Limin Gong, Yuandong Fu, Minyi Qian   +4 more
wiley   +1 more source

The Synthesis of Bicyclo[1.1.1]pentane-Containing Aromatic Lipoxin Analogues

, 2023
The two lipoxins, lipoxin A4 and lipoxin B4, are members of an important class of endogenously-derived natural products called specialised pro-resolving mediators (SPMs) that are known to play a crucial role in the resolution of inflammation.
Owen, Benjamin
core  

Mechanistic Pathways of Wound Healing: From Hemostasis to Scar‐Free Regeneration

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Wound healing is the critical process regulated through a harmonious coordination of cellular, molecular, pathological, and systemic communications. Normally, healing occurs in four overlapping phases, which are modified and controlled by various growth factor interactions and signaling pathways.
Devadass Jessy Mercy, Koyeli Girigoswami, Agnishwar Girigoswami   +2 more
wiley   +1 more source