Results 81 to 90 of about 7,978 (212)
A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae
Nature Communications, 2015 Exposure of Anopheles gambiae mosquitoes to Plasmodium infection enhances the ability of their immune system to respond to subsequent infections. However, the molecular mechanism that allows the insect innate immune system to ‘remember’ a previous ...
Jose Luis Ramirez +7 more
doaj +1 more source
The Roles of EETs in Neurological Disorders
CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.Epoxyeicosatrienoic acids (EETs), derived from arachidonic acid (ARA) via cytochrome P450 (CYP450) enzymes, are produced in nearly all human tissues and exert a wide range of beneficial effects. This review summarizes the roles and potential mechanisms of EETs in neurological disorders, with a focus on cerebrovascular diseases, epilepsy, Parkinson's ...
Rong Tang +6 more
wiley +1 more source
Studies to Characterize the Neuroprotective Targets of Lipoxin B4 [PDF]
, 2021 Recent discoveries have shown that lipoxin A4 (LXA4) and lipoxin B4 (LXB4) in astrocyte conditioned media that conferred neuroprotection in vivo and in vitro.
Kim, Changmo
core +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
MedComm, Volume 7, Issue 9, September 2026.This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Synthese von optisch aktivem 9,14-Methylen- Lipoxin A 4
, 2008 In der vorliegenden Arbeit wurde die Synthese von optisch aktivem 9,14-Methylen-Lipoxin A4 untersucht. Lipoxin A4 und seine Derivate leiten sich von der Arachidonsäurekaskade ab wie die Prostaglandine, Prostacycline, Thromboxana und Leucotriene.
Duymaz, Adile
core +1 more source
Frontiers in ImmunologyBackgroundSARS-CoV-2, the causative virus of the COVID-19 global pandemic, leads to a wide variety of responses among patients. Some of them present a very severe phenotype, while others only experience mild symptoms or are even asymptomatic.
Sergio Sánchez-García +12 more
doaj +1 more source
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek +1 more
wiley +1 more source
Conversion of 5,6-dihydroxyeicosatetraenoic acids A novel pathway for lipoxin formation by human platelets [PDF]
, 1992 Leukotriene A4 may be metabolized to 5(S),6(R)- and 5(S),6(S)-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acids by enzymatic or non-enzymatic hydrolysis.
Gigou, Agnès +9 more
core +1 more source
Effect of Lipoxin A4 on bleomycin induced cytotoxicity in IMR-32 cells.
, 2014 (A) Effect of pre-treatment with different doses (1, 5, 10 ng/ml) of lipoxin A4 on bleomycin (60 µg/ml) induced cytotoxicity to IMR-32 cells. Cells were pre incubated with lipoxin A4 for 5 hrs and then bleomycin for 24 hrs. MTT assay was performed.
Arul M. Mani (678608) +5 more
core +1 more source
Apoptosis-associated biomarkers in tuberculosis: promising for diagnosis and prognosis prediction
BMC Infectious Diseases, 2013 Background Apoptosis-associated biomarkers are rarely studied, especially their role in predicting the development of tuberculosis (TB) from latent TB infection and in prognostication.
Shu Chin-Chung +8 more
doaj +1 more source