Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan [PDF]
Clinical and Molecular HepatologyBackground/Aims Steatotic liver disease (SLD) is a common manifestation in chronic hepatitis C (CHC). Metabolic alterations in CHC are associated with metabolic dysfunction-associated steatotic liver disease (MASLD).
Chung-Feng Huang +14 more
doaj +1 more source
A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative [PDF]
, 2016 Recent improvements in next-generation sequencing (NGS) technology have enabled detection of biomarkers in cell-free DNA in blood and may ultimately replace invasive tissue biopsies.
Aberra, Metasebia +15 more
core +2 more sources
Cancer metabolites: promising biomarkers for cancer liquid biopsy
Biomarker Research, 2023 Cancer exerts a multitude of effects on metabolism, including the reprogramming of cellular metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of cancer cells and adaptation to the tumor microenvironment.
Wenxiang Wang +5 more
semanticscholar +1 more source
Computational and Structural Biotechnology Journal, 2023 Early diagnosis and progression assessment are critical for the timely detection and treatment of gastric cancer (GC) patients. Identification of diagnostic biomarkers for early detection of GC represents an unmet clinical need, and how these markers ...
Fei Long +9 more
doaj +1 more source
Molecular Oncology, 2020 Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC) initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be involved in HCC. In this study, we explored how lncRNA LINC00662 may influence HCC
Xiaohui Tian +7 more
doaj +1 more source
NULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing
Nature Communications, 2023 The blood proteome holds great promise for precision medicine but poses substantial challenges due to the low abundance of most plasma proteins and the vast dynamic range of the plasma proteome.
Wei Feng +35 more
semanticscholar +1 more source
Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer
Biomedicines, 2021 Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer.
Patricia Mondelo-Macía +6 more
doaj +1 more source
Emergence of Extracellular Vesicles as “Liquid Biopsy” for Neurological Disorders: Boom or Bust
Pharmacological Reviews, 2023 Extracellular vesicles (EVs) have emerged as an attractive liquid biopsy approach in the diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching specific subpopulations of EVs from biofluids based on their unique surface ...
Ashish Kumar +2 more
semanticscholar +1 more source
Sensitivity of activated human lymphocytes to cyclosporine and its metabolites [PDF]
, 1988 Alloreactive T cells generated as clones from mixed lymphocyte cultures, or propagated from heart or liver transplant biopsies, were tested for secondary proliferation measured in the primed lymphocyte test in the presence of Cyclosporine A and ...
Burckart, G +8 more
core +1 more source
Frontiers in Public Health, 2023 ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han +5 more
doaj +1 more source