Results 31 to 40 of about 2,946,879 (341)

Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy

Journal for ImmunoTherapy of Cancer, 2023
Circulating cell-free tumor DNA (ctDNA) can serve as a real-time biomarker of tumor burden and provide unique insights into the evolving molecular landscape of cancers under the selective pressure of immunotherapy.
L. Sivapalan, J. Murray, Jenna V. Canzoniero, Blair V. Landon, Jennifer Jackson, Susan L. Scott, V. Lam, B. Levy, M. Sausen, V. Anagnostou   +9 more
semanticscholar   +1 more source

Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan [PDF]

Clinical and Molecular Hepatology
Background/Aims Steatotic liver disease (SLD) is a common manifestation in chronic hepatitis C (CHC). Metabolic alterations in CHC are associated with metabolic dysfunction-associated steatotic liver disease (MASLD).
Chung-Feng Huang, Chia-Yen Dai, Yi-Hung Lin, Chih-Wen Wang, Tyng-Yuan Jang, Po-Cheng Liang, Tzu-Chun Lin, Pei-Chien Tsai, Yu-Ju Wei, Ming-Lun Yeh, Ming-Yen Hsieh, Chao-Kuan Huang, Jee-Fu Huang, Wan-Long Chuang, Ming-Lung Yu   +14 more
doaj   +1 more source

NULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing

Nature Communications, 2023
The blood proteome holds great promise for precision medicine but poses substantial challenges due to the low abundance of most plasma proteins and the vast dynamic range of the plasma proteome.
Wei Feng, Joanne C. Beer, Qinyu Hao, Ishara S. Ariyapala, Aparna Sahajan, Andrei Komarov, Katie Cha, Mason Moua, Xiaolei Qiu, Xiaomei Xu, Shweta Iyengar, Thu Yoshimura, Rajini Nagaraj, Li Wang, Ming Yu, Kate Engel, Lucas Zhen, Wen Xue, Chen-jung Lee, Chan Ho Park, Cheng Peng, Kai-lun Zhang, Adrian Grzybowski, J. Hahm, Susanne V. Schmidt, Alexandru Odainic, Jasper Spitzer, K. Buddika, Dwight Kuo, Lei Fang, Bingqing Zhang, Steve Chen, E. Latz, Yiyuan Yin, Yuling Luo, Xiao-Jun Ma   +35 more
semanticscholar   +1 more source

Long noncoding RNA LINC00662 promotes M2 macrophage polarization and hepatocellular carcinoma progression via activating Wnt/β‐catenin signaling

Molecular Oncology, 2020
Tumor‐associated macrophages have important roles in hepatocellular carcinoma (HCC) initiation and progression. Long noncoding RNAs (lncRNAs) have also been reported to be involved in HCC. In this study, we explored how lncRNA LINC00662 may influence HCC
Xiaohui Tian, Yuanyuan Wu, Yating Yang, Jiaxin Wang, Menglan Niu, Shanjun Gao, Tao Qin, Dengke Bao   +7 more
doaj   +1 more source

Liquid Biopsy in Neurological Diseases

Cells, 2023
The most recent and non-invasive approach for studying early-stage biomarkers is liquid biopsy. This implies the extraction and analysis of non-solid biological tissues (serum, plasma, saliva, urine, and cerebrospinal fluid) without undergoing invasive ...
S. Malhotra, Mari Carmen Martín Miras, A. Pappolla, X. Montalban, M. Comabella   +4 more
semanticscholar   +1 more source

Current Status and Future Perspectives of Liquid Biopsy in Small Cell Lung Cancer

Biomedicines, 2021
Approximately 19% of all cancer-related deaths are due to lung cancer, which is the leading cause of mortality worldwide. Small cell lung cancer (SCLC) affects approximately 15% of patients diagnosed with lung cancer.
Patricia Mondelo-Macía, Jorge García-González, Luis León-Mateos, Adrián Castillo-García, Rafael López-López, Laura Muinelo-Romay, Roberto Díaz-Peña   +6 more
doaj   +1 more source

Mechanobiology and survival strategies of circulating tumor cells: a process towards the invasive and metastatic phenotype

Frontiers in Cell and Developmental Biology, 2023
Metastatic progression is the deadliest feature of cancer. Cancer cell growth, invasion, intravasation, circulation, arrest/adhesion and extravasation require specific mechanical properties to allow cell survival and the completion of the metastatic ...
Keerthi Kurma, Keerthi Kurma, Keerthi Kurma, Catherine Alix-Panabières, Catherine Alix-Panabières, Catherine Alix-Panabières   +5 more
doaj   +1 more source

Exosomes as a new frontier of cancer liquid biopsy

Molecular Cancer, 2022
Liquid biopsy, characterized by minimally invasive detection through biofluids such as blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and prognosis prediction.
Dan Yu, Yixin Li, Maoye Wang, Jianmei Gu, Wenrong Xu, Huisi Cai, Xinjian Fang, Xu Zhang   +7 more
semanticscholar   +1 more source

Cost-effectiveness analysis of capecitabine maintenance therapy plus best supportive care vs. best supportive care alone as first-line treatment of newly diagnosed metastatic nasopharyngeal carcinoma

Frontiers in Public Health, 2023
ObjectivesMaintenance therapy with capecitabine after induction chemotherapy for patients with newly diagnosed metastatic nasopharyngeal carcinoma (mNPC) has been confirmed to be effective.
Jiaqi Han, Xiaomeng Lan, Kun Tian, Xi Shen, Jinlan He, Nianyong Chen   +5 more
doaj   +1 more source

Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

Molecular Cancer, 2022
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy.
S. N. Lone, Sabah Nisar, Tariq Ahmad Masoodi, Mayank Singh, Arshi Rizwan, Sheema Hashem, W. El-Rifai, D. Bedognetti, S. Batra, Mohammad Haris, A. Bhat, M. Macha   +11 more
semanticscholar   +1 more source