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What information could the main actors of liquid biopsy provide? A representative case of non-small cell lung cancer (NSCLC) [PDF]

open access: yes, 2018
In non-small cell lung cancer (NSCLC), there is a consensus regarding the use of liquid biopsy, generally, to detect "druggable" mutations and, in particular, to monitor tyrosine kinase inhibitor (TKI) treatments. However, whether circulating tumor cells
Manicone, M.   +6 more
core   +1 more source

Recent advances of liquid biopsy: Interdisciplinary strategies toward clinical decision‐making

open access: yesInterdisciplinary Medicine, 2023
Liquid biopsy has emerged as a promising avenue for non‐invasive and rapid retrieval of pathological information from patient body fluids. Over the years, liquid biopsy has garnered significant attention for clinically treating cancer by selecting ...
Han Bao   +4 more
semanticscholar   +1 more source

Malignancy risk analysis in patients with inadequate fine needle aspiration cytology (FNAC) of the thyroid [PDF]

open access: yes, 2012
Background Thyroid fine needle aspiration cytology (FNAC) is the standard diagnostic modality for thyroid nodules. However, it has limitations among which is the incidence of non-diagnostic results (Thy1).
A Bakshi   +51 more
core   +6 more sources

Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma

open access: yesCell Death and Disease, 2021
TEFM (transcription elongation factor of mitochondria) has been identified as a novel nuclear-encoded transcription elongation factor in the transcription of mitochondrial genome.
Lixin Wan   +11 more
doaj   +1 more source

Liquid biopsy on the horizon in immunotherapy of non-small cell lung cancer: current status, challenges, and perspectives

open access: yesCell Death and Disease, 2023
Non-small cell lung cancer (NSCLC) is one of the most threatening malignancies to human health and life. In most cases, patients with NSCLC are already at an advanced stage when they are diagnosed.
Yingtao Yang   +6 more
semanticscholar   +1 more source

Toward Personalized Nanomedicine: The Critical Evaluation of Micro and Nanodevices for Cancer Biomarker Analysis in Liquid Biopsy.

open access: yesSmall, 2023
Liquid biopsy for the analysis of circulating cancer biomarkers (CBs) is a major advancement toward the early detection of cancer. In comparison to tissue biopsy techniques, liquid biopsy is relatively painless, offering multiple sampling opportunities ...
Kimberley Clack   +5 more
semanticscholar   +1 more source

NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment

open access: yesMolecular Oncology, 2021
Despite impressive and durable responses, nonsmall cell lung cancer (NSCLC) patients treated with anaplastic lymphoma kinase (ALK) inhibitors (ALK‐Is) ultimately progress due to development of resistance.
Estela Sánchez‐Herrero   +17 more
doaj   +1 more source

Focused ultrasound-enabled brain tumor liquid biopsy [PDF]

open access: yes, 2018
Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors.
Chen, Hong   +10 more
core   +3 more sources

Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology

open access: yesBiomarker Research, 2023
While the field of precision oncology is rapidly expanding and more targeted options are revolutionizing cancer treatment paradigms, therapeutic resistance particularly to immunotherapy remains a pressing challenge.
Karama Asleh   +5 more
semanticscholar   +1 more source

Liquid biopsy genotyping in lung cancer: ready for clinical utility? [PDF]

open access: yes, 2017
Liquid biopsy is a blood test that detects evidence of cancer cells or tumor DNA in the circulation. Despite complicated collection methods and the requirement for technique-dependent platforms, it has generated substantial interest due, in part, to its ...
Chen, Yi-Lin   +7 more
core   +1 more source

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