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Beyond blood: Advancing the frontiers of liquid biopsy in oncology and personalized medicine
Cancer ScienceLiquid biopsy is emerging as a pivotal tool in precision oncology, offering a noninvasive and comprehensive approach to cancer diagnostics and management.
Ying Bao +3 more
semanticscholar +1 more source
Advances in Liquid Biopsy Technology and Implications for Pancreatic Cancer
International Journal of Molecular Sciences, 2023 Pancreatic cancer is a highly aggressive malignancy with a climbing incidence. The majority of cases are detected late, with incurable locally advanced or metastatic disease.
A. Raufi +4 more
semanticscholar +1 more source
Liquid Biopsy in Oral Cancer [PDF]
International Journal of Molecular Sciences, 2018 Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a complex process, in which heterogeneity plays an important role in the development and progression of the disease. This review provides an overview of the current biological and clinical significance of circulating tumour cells (CTCs), circulating tumour DNA (ctDNA),
Óscar Rapado-González +6 more
openaire +3 more sources
Functional characterization of infiltrating T lymphocytes in human hepatic allografts [PDF]
, 1986 We have employed recently developed techniques in T-cell culturing to study the nature and function of infiltrating hepatic allograft T cells. Using the rationale that intragraft T cells are activated during cell mediated damage to the allograft, we were
Adriana Zeevi +53 more
core +1 more source
Cost-Effectiveness of Liquid Biopsy for Colorectal Cancer Screening in Patients Who Are Unscreened
JAMA Network Open, 2023 Key Points Question Is liquid biopsy testing a cost-effective method for colorectal cancer screening, particularly in patients who refuse traditional screening methods?
Zainab Aziz +9 more
semanticscholar +1 more source
Liquid biopsies for bladder cancer [PDF]
Translational Andrology and Urology, 2017 The development of accurate urinary biomarkers for the non-invasive detection of urothelial bladder cancer (UBC) could transform patient pathways by reducing reliance on cystoscopy, and the identification of highly prognostic (or even predictive) biomarkers could better guide patient management.
Richard T. Bryan, Douglas G. Ward
openaire +3 more sources
Total Number of Alterations in Liquid Biopsies Is an Independent Predictor of Survival in Patients With Advanced Cancers. [PDF]
, 2020 PurposeStudies have demonstrated an association between quantity of circulating tumor DNA (ctDNA) and poorer survival. We investigated the relationship between percent ctDNA (%ctDNA), total number of ctDNA alterations, and overall survival (OS) in liquid
Goodman, Aaron +4 more
core
Nano ConvergenceLiquid biopsy has emerged as a promising non-invasive strategy for cancer diagnosis, enabling the detection of various circulating biomarkers, including circulating tumor cells (CTCs), circulating tumor nucleic acids (ctNAs), circulating tumor-derived ...
Nana Lyu +4 more
semanticscholar +1 more source
Leukemia, 2023 In the present study, we screened 84 Follicular Lymphoma patients for somatic mutations suitable as liquid biopsy MRD biomarkers using a targeted next-generation sequencing (NGS) panel. We found trackable mutations in 95% of the lymph node samples and 80%
A. Jiménez-Ubieto +27 more
semanticscholar +1 more source
Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]
, 2019 Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C +4 more
core +2 more sources