Results 111 to 120 of about 11,750 (172)

Precise physical models of protein-DNA interaction from high-throughput data [PDF]

, 2007
A cell's ability to regulate gene transcription depends in large part on the energy with which transcription factors (TFs) bind their DNA regulatory sites.
Kinney, J. B., Tkacik, G., Callan, C. G.   +2 more
core   +1 more source

Memory NK cell features exploitable in anticancer immunotherapy [PDF]

, 2019
Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone, Capuano, Cristina, Galandrini, Ricciarda, Palmieri, Gabriella, Pighi, Chiara, Santoni, Angela   +5 more
core   +2 more sources

Identification of Key Genes and Potential Mechanisms Based on the Autophagy Regulatory Network in Osteoclasts Using a Murine Osteoarthritis Model

Journal of Inflammation Research, 2022
Haifeng Zhang,* Houyi Sun,* Wei Zhang,* Yaozeng Xu, Dechun Geng Department of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou City, People’s Republic of China*These authors contributed equally to this workCorrespondence ...
Zhang H, Sun H, Zhang W, Xu Y, Geng D
doaj  

Les transferts de biens et les paiements de soutien entre concubins : une analyse des dispositions fiscales [PDF]

, 1983
Until recently, the Income Tax Act and its provincial counterpart had refused the common law spouses the tax treatment granted to « legal » spouses. Modifications were introduced in two specific areas of the act allowing these « outlaws » firstly a tax ...
Lareau, André
core   +1 more source

Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice

American Journal of Physiology-Cell Physiology
Having identified LC3-interacting region (LIR) motifs 1/2 of A20 binding inhibitor of NF-κB-1 (ABIN-1) as mitophagy regulators in vitro, this study generated CRISPR-engineered ABIN1-ΔLIR1/2 mice lacking both LIR motifs to elucidate its in vivo significance.
Lisa Sophie Huber, Rosetta Merline, Jinyang Zeng-Brouwers, Rajkumar Vutukuri, Nico Kraus, Cristina Ortiz, Stefan Guenther, Eva Miriam Buhl, Lisa Hahnefeld, Robert Gurke, Julia Bein, Madina Karimova, Patrick Wurzel, Peter Boor, Christoph Welsch, Peter Wild, Josef Pfeilschifter, Donat Kögel, Malgorzata Wygrecka, Jonel Trebicka, Rafal Bartoszewski, Ivan Dikic, Liliana Schaefer   +22 more
openaire   +1 more source

State College Times, March 2, 1934 [PDF]

, 1934
Volume 22, Issue 85https://scholarworks.sjsu.edu/state_college_times_1934/1035/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +4 more sources

Duck STING mediates antiviral autophagy directing the interferon signaling pathway to inhibit duck plague virus infection

Veterinary Research
Migratory birds are important vectors for virus transmission, how migratory birds recognize viruses and viruses are sustained in birds is still enigmatic.
Bin Tian, Yanming Tian, Xuetong Wang, Dongjie Cai, Liping Wu, Mingshu Wang, Renyong Jia, Shun Chen, Dekang Zhu, Mafeng Liu, Qiao Yang, Ying Wu, Xinxin Zhao, Shaqiu Zhang, Di Sun, Juan Huang, Xumin Ou, Zhen Wu, Anchun Cheng   +18 more
doaj   +1 more source

Non-cytopathic bovine viral diarrhea virus (BVDV) inhibits innate immune responses via induction of mitophagy

Veterinary Research
Bovine viral diarrhea virus (BVDV) belongs to the genus Pestivirus within the family Flaviviridae. Mitophagy plays important roles in virus-host interactions.
Zhijun Li, Ying Zhang, Bao Zhao, Qinghong Xue, Chunjiang Wang, Siyu Wan, Jingyu Wang, Xiwen Chen, Xuefeng Qi   +8 more
doaj   +1 more source

Reticulophagy receptor FAM134C restrains BMP receptor signaling

The EMBO Journal
FAM134/RETREG family members are ER-phagy receptors that maintain cellular homeostasis by regulating endoplasmic reticulum turnover. However, possible non-ER-phagy functions of FAM134 proteins remain elusive.
Shuchen Gu, Hanchenxi Zhang, Jin Cao, Zhou He, Jianfeng Wu, Xia Liu, Mingjie Zheng, Ting Liu, Bin Zhao, Pinglong Xu, Qiming Sun, Jianping Jin, Xia Lin, Yi Yu, Jiahuai Han, Xin-Hua Feng   +15 more
doaj   +1 more source

Differential roles of N- and C-terminal LIR motifs in the catalytic activity and membrane targeting of RavZ and ATG4B proteins. [PDF]

BMB Rep
Mammalian ATG8 proteins (mATG8s) are essential for selective autophagy because they recruit various proteins with LC3- interacting region (LIR) motifs to autophagic membranes. The RavZ protein, secreted by Legionella pneumophila, and mammalian ATG4B possess functional LIR motifs that participate in lipidated mATG8 deconjugation on autophagic membranes.
Park SW, Park JH, Choi H, Jeon P, Lee SH, Shin WD, Kim HJ, Lee JA, Jang DJ.   +8 more
europepmc   +3 more sources