Results 91 to 100 of about 11,750 (172)

From Bug to Feature: Harnessing Cross‐Sensitivity for Multiparametric Luminescence Sensing

Advanced Functional Materials, Volume 36, Issue 35, 30 April 2026.
Cross‐sensitivity in luminescence sensing is reframed from a limitation into a resource for multiparametric detection. Using ruby microspheres as a model system, cross‐sensitivity is quantitatively assessed and exploited through linear discriminant analysis, enabling simultaneous, correction‐free pressure and temperature sensing with a single ...
Nikita Panov, Liyan Ming, Stanislav Sinogeikin, Erving Ximendes, Daniel Jaque, Riccardo Marin   +5 more
wiley   +1 more source

YIPF3 and YIPF4 regulate autophagic turnover of the Golgi apparatus

The EMBO Journal
The degradation of organelles by autophagy is essential for cellular homeostasis. The Golgi apparatus has recently been demonstrated to be degraded by autophagy, but little is known about how the Golgi is recognized by the forming autophagosome.
Shinri Kitta, Tatsuya Kaminishi, Momoko Higashi, Takayuki Shima, Kohei Nishino, Nobuhiro Nakamura, Hidetaka Kosako, Tamotsu Yoshimori, Akiko Kuma   +8 more
doaj   +1 more source

An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor [PDF]

, 2016
Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds
Altschul, Bassham, Baxt, Berrow, Birgisdottir, Boyle, Bozkurt, Bozkurt, Bozkurt, Caillaud, Chaparro-Garcia, Choy, Dagdas, Fisher, Geldner, Hanamata, He, Huang, Ivanov, Kalvari, Karimi, Kumar, Kwon, Lamb, Larkin, Lenz, Li, Lipka, Liu, Lv, Morgan, Mostowy, Oh, Patel, Petre, Randow, Randow, Saunders, Segonzac, Shintani, Song, Stolz, Svenning, Teh, Vanhee, Wang, Win, Yoshimoto, Zientara-Rytter   +48 more
core   +2 more sources

Advances in Crohn's Disease: A Comprehensive Review of Pathophysiology, Diagnosis, and Emerging Therapeutics

JGH Open, Volume 10, Issue 4, April 2026.
ABSTRACT Crohn's disease (CD) is a chronic inflammatory condition of the bowel with a rising global incidence. Its complex etiology involves genetic susceptibility, environmental factors, and alterations in the gut microbiota, leading to dysregulated immune responses.
Yoon‐Kyo An, Robert Gilmore, Graham Radford‐Smith, Jakob Begun   +3 more
wiley   +1 more source

State College Times, May 20, 1932 [PDF]

, 1932
Volume 20, Issue 67https://scholarworks.sjsu.edu/spartan_daily_1932/1049/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +4 more sources

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, Volume 293, Issue 8, Page 2314-2340, April 2026.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins

eLife, 2017
Autophagy is a conserved cellular process involved in the elimination of proteins and organelles. It is also used to combat infection with pathogenic microbes.
Aimin Yang, Supansa Pantoom, Yao-Wen Wu
doaj   +1 more source

A guide to chemokines and their receptors [PDF]

, 2018
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G‐protein coupled heptahelical chemokine receptors.
Braun A, Dyer DP, Garton KJ, Gupta SK, Hundelshausen P, Janssens R, Murphy PM, Sozzani S, Speck RF, Suan D, Woollard SM, Zheng Y   +11 more
core   +1 more source

Current perspectives on KMT2A fusion proteins and menin inhibition in paediatric acute myeloid leukaemia

The FEBS Journal, Volume 293, Issue 8, Page 2159-2177, April 2026.
Genetic rearrangements resulting in the expression of KMT2A fusion alleles can lead to dramatic transcriptional disturbances that contribute to the onset of acute leukaemias. Fortunately, menin inhibition has emerged as a promising new class of targeted therapy.
Lydia Elaine Roets, Graeme Greenfield, Katrina Mairead Lappin   +2 more
wiley   +1 more source

ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling [PDF]

, 2016
The transcription factor Nrf2 and its repressor protein Keap1 play key roles in the regulation of antioxidant stress responses and both Keap1-Nrf2 signalling and oxidative stress have been implicated in the pathogenesis of the ALS-FTLD spectrum of ...
Alice Goode, Almeida, Bae, Bakkar, Barry Shaw, Bergstrom, Copple, Fourquet, Goode, Goode, Guo, Ichimura, Jain, Kim, Kobayashi, Komatsu, Lau, Li, Majcher, Mark S. Searle, McGown, McMahon, Melanie Sultana, Milani, Miller, Mimoto, Najat, Pajares, Pankiv, Petri, Rea, Rea, Robert Layfield, Rubino, Sarah Rea, Sarlette, Tanji, Tanji, Tong, Vargas, Wang, Wang, Wright, Zhang   +43 more
core   +2 more sources