Results 81 to 90 of about 11,750 (172)

The autophagosome:current understanding of formation and maturation [PDF]

open access: yes, 2015
Autophagy is an important and highly conserved catabolic process with roles in development, homeostasis, and cellular stress responses. It describes various distinct pathways for the delivery of cytoplasmic materials (including misfolded protein ...
Lane, Jon D, Mannack, Lilith V J
core   +2 more sources

Proteolytic control of mitochondrial protein translocases

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Lara Kroczek, Thomas Langer
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska   +6 more
wiley   +1 more source

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription. [PDF]

open access: yesPLoS ONE, 2012
Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified.
Ana Sancho   +13 more
doaj   +1 more source

Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses [PDF]

open access: yes, 2017
Selective autophagy is a catabolic process with which cellular material is specifically targeted for degradation by lysosomes. The function of selective autophagic degradation of self-components in the regulation of innate immunity is still unclear. Here
Bowitz Larsen, Kenneth   +6 more
core   +3 more sources

Combined Retrieval of Cloud Parameters for TEMPO Measurements Over Canada Using Oxygen Dimer and B Band Absorption

open access: yesEarth and Space Science, Volume 13, Issue 5, May 2026.
Abstract Tropospheric Emissions: Monitoring of Pollution (TEMPO) provides valuable hourly measurements of airborne pollutants over North America. Data quality over snowy surfaces may degrade due to difficulty in accurately characterizing surface reflectivity and cloud properties, as snow and cloud are both highly reflective and therefore challenging to
Lukas Fehr   +8 more
wiley   +1 more source

LDHB suppresses the PDCoV proliferation by targeting viral nucleocapsid protein for autophagic degradation

open access: yesMicrobiology Spectrum
Porcine deltacoronavirus (PDCoV) is a newly identified enteric coronavirus that causes serious diarrhea and vomiting in pigs, leading to substantial economic losses globally.
Xiaohan Wu   +9 more
doaj   +1 more source

Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3

open access: yesCell Reports, 2016
Autophagy is a conserved catabolic process that plays a housekeeping role in eliminating protein aggregates and organelles and is activated during nutrient deprivation to generate metabolites and energy.
Marina N. Sharifi   +7 more
doaj   +1 more source

Tin‐Oxo Nanocluster Extreme UV Photoresists Equipped with Chemical Features for Atmospheric Stability and High EUV Sensitivity

open access: yesAdvanced Functional Materials, Volume 36, Issue 27, 2 April 2026.
Fluoroalkyl‐functionalized tin–oxo nanoclusters (N‐TOC6) enable robust pattern formation through ligand crosslinking under EUV exposure without thermal processing. Sn–F coordination mitigates the Lewis acidity of Sn centers, suppressing reactions with airborne molecules and improving post‐exposure pattern stability.
Yejin Ku   +18 more
wiley   +1 more source

CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis [PDF]

open access: yes, 2018
Mechanisms of selective autophagy of the ER, known as ER-phagy, require molecular delineation, particularly in vivo. It is unclear how these events control ER proteostasis and cellular health.
Adamson   +87 more
core   +1 more source

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