Results 61 to 70 of about 240,005 (160)

Herpesvirus lytic infection-induced mitophagy via viral interferon regulatory factor 1

open access: yesAutophagy Reports, 2023
Viral control of mitochondria via mitophagy has a dampening effect on mitochondrion-mediated innate immune responses. We previously found that human herpesvirus 8 (HHV-8) could activate mitophagy via its lytic gene product vIRF-1 (viral interferon ...
Mai Tram Vo, Young Bong Choi
doaj   +1 more source

Improved Post‐Processing Framework for Whole Slide Imaging and 3D Reconstruction

open access: yesMicroscopy Research and Technique, EarlyView.
Workflow for 3D reconstruction of marmoset whole‐slide histology. Individual tiles undergo vignette correction to address illumination artifacts before stitching into full‐section images. Sections are then reconstructed using the Possum framework, with a level‐set method incorporated at the nonlinear deformable stage to stabilize alignment and reduce ...
Emily L. De Leon Alvarado   +8 more
wiley   +1 more source

Concordance Between MR Safety Guidance Documents on Conditions for a Safe MR Environment

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Environmental conditions established at facility design, construction, updates, and/or procurement of specialized equipment are the foundation of safe MR practice. Establishing an institutional MR safety program must take into consideration the conditions of the MR environment, and staff training should be tailored to its features ...
Ives R. Levesque   +3 more
wiley   +1 more source

Recent advances in polymeric chemically amplified positive resists: Materials and design strategies

open access: yesSmart Molecules, EarlyView.
This review summarizes recent advances in the molecular design of positive chemically amplified resists, focusing on photoacid generators and polymer architectures. Key strategies for enhancing sensitivity—including self‐amplification effects, copolymerization of sensitive monomers, controlled polymerization, and photosensitized chemically amplified ...
Litao Zhou   +3 more
wiley   +1 more source

A joint model of cost and churn for the insurance industry

open access: yesJournal of Risk and Insurance, EarlyView.
Abstract In insurance markets, claim costs are highly variable, heavy‐tailed, and difficult to predict. At the same time, policyholder retention and lapse behavior (customer churn) are critical determinants of long‐term profitability and solvency. Most existing models in the literature treat claim costs and lapses as independent, overlooking potential ...
Yumo Dong   +4 more
wiley   +1 more source

Lost in translation? Injunctions and patent enforcement in a transatlantic perspective

open access: yesThe Journal of World Intellectual Property, EarlyView.
Abstract As the European Directive on the Enforcement of Intellectual Property Rights (IPRED) marked the twentieth anniversary of its adoption, renewed calls have emerged for its revision, aimed at fostering a more effective application of the principle of proportionality in patent enforcement.
Giuseppe Colangelo
wiley   +1 more source

Copyright Literacy in the UK: a survey of librarians and other cultural heritage sector professionals [PDF]

open access: yes, 2015
Based on a survey of UK library and information professionals and those who work in the cultural heritage sector, carried out in December 2014, this research sought to examine the levels of copyright „literacy?.
Secker, Jane   +3 more
core   +1 more source

Harnessing Bulk‐Segregant Mapping to Identify Trait‐Associated Genes in the Allopolyploid Model Plant Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Forward genetics has been instrumental in identifying genes underlying desirable traits, yet its application to polyploid plants, many of which are key agricultural crops, remains challenging due to their genomic complexity. Therefore, we developed BenthMap, a bulk segregant analysis platform for high‐throughput trait mapping and gene ...
Zuba Ahmed   +5 more
wiley   +1 more source

MEME-LaB : motif analysis in clusters [PDF]

open access: yes, 2013
Genome-wide expression analysis can result in large numbers of clusters of co-expressed genes. While there are tools for ab initio discovery of transcription factor binding sites, most do not provide a quick and easy way to study large numbers of ...
Paul Brown   +11 more
core   +1 more source

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription. [PDF]

open access: yesPLoS ONE, 2012
Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified.
Ana Sancho   +13 more
doaj   +1 more source

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