Herpesvirus lytic infection-induced mitophagy via viral interferon regulatory factor 1
Viral control of mitochondria via mitophagy has a dampening effect on mitochondrion-mediated innate immune responses. We previously found that human herpesvirus 8 (HHV-8) could activate mitophagy via its lytic gene product vIRF-1 (viral interferon ...
Mai Tram Vo, Young Bong Choi
doaj +1 more source
Improved Post‐Processing Framework for Whole Slide Imaging and 3D Reconstruction
Workflow for 3D reconstruction of marmoset whole‐slide histology. Individual tiles undergo vignette correction to address illumination artifacts before stitching into full‐section images. Sections are then reconstructed using the Possum framework, with a level‐set method incorporated at the nonlinear deformable stage to stabilize alignment and reduce ...
Emily L. De Leon Alvarado +8 more
wiley +1 more source
Concordance Between MR Safety Guidance Documents on Conditions for a Safe MR Environment
ABSTRACT Background Environmental conditions established at facility design, construction, updates, and/or procurement of specialized equipment are the foundation of safe MR practice. Establishing an institutional MR safety program must take into consideration the conditions of the MR environment, and staff training should be tailored to its features ...
Ives R. Levesque +3 more
wiley +1 more source
Recent advances in polymeric chemically amplified positive resists: Materials and design strategies
This review summarizes recent advances in the molecular design of positive chemically amplified resists, focusing on photoacid generators and polymer architectures. Key strategies for enhancing sensitivity—including self‐amplification effects, copolymerization of sensitive monomers, controlled polymerization, and photosensitized chemically amplified ...
Litao Zhou +3 more
wiley +1 more source
A joint model of cost and churn for the insurance industry
Abstract In insurance markets, claim costs are highly variable, heavy‐tailed, and difficult to predict. At the same time, policyholder retention and lapse behavior (customer churn) are critical determinants of long‐term profitability and solvency. Most existing models in the literature treat claim costs and lapses as independent, overlooking potential ...
Yumo Dong +4 more
wiley +1 more source
Lost in translation? Injunctions and patent enforcement in a transatlantic perspective
Abstract As the European Directive on the Enforcement of Intellectual Property Rights (IPRED) marked the twentieth anniversary of its adoption, renewed calls have emerged for its revision, aimed at fostering a more effective application of the principle of proportionality in patent enforcement.
Giuseppe Colangelo
wiley +1 more source
Copyright Literacy in the UK: a survey of librarians and other cultural heritage sector professionals [PDF]
Based on a survey of UK library and information professionals and those who work in the cultural heritage sector, carried out in December 2014, this research sought to examine the levels of copyright „literacy?.
Secker, Jane +3 more
core +1 more source
ABSTRACT Forward genetics has been instrumental in identifying genes underlying desirable traits, yet its application to polyploid plants, many of which are key agricultural crops, remains challenging due to their genomic complexity. Therefore, we developed BenthMap, a bulk segregant analysis platform for high‐throughput trait mapping and gene ...
Zuba Ahmed +5 more
wiley +1 more source
MEME-LaB : motif analysis in clusters [PDF]
Genome-wide expression analysis can result in large numbers of clusters of co-expressed genes. While there are tools for ab initio discovery of transcription factor binding sites, most do not provide a quick and easy way to study large numbers of ...
Paul Brown +11 more
core +1 more source
DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription. [PDF]
Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified.
Ana Sancho +13 more
doaj +1 more source

