Results 41 to 50 of about 240,005 (160)
Cell Reports, 2020 Summary: Autophagy is the degradation of cytoplasmic material through the lysosomal pathway. One of the most studied autophagy-related proteins is LC3.
Anne-Claire Jacomin +13 more
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Autophagy Reports, 2023 MTFP1 (mitochondrial fission process 1), an inner mitochondrial membrane protein, plays a crucial role in mitochondrial fission to maintain mitochondrial morphology.
Debasna P Panigrahi, Sujit K Bhutia
doaj +1 more source
Acta Pharmaceutica Sinica B, 2022 Chemoresistance remains a major obstacle to successful treatment of triple negative breast cancer (TNBC). Identification of druggable vulnerabilities is an important aim for TNBC therapy.
Minmin Fan +10 more
doaj +1 more source
Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases
Neurobiology of Disease, 2019 Over the past 20 years, the concept of mammalian autophagy as a nonselective degradation system has been repudiated, due in part to important discoveries in neurodegenerative diseases, which opened the field of selective autophagy. Protein aggregates and
Charleen T. Chu
doaj +1 more source
, 2021 Abstract Previously, we and other investigators have demonstrated that phosphorylated microtubule-associated protein 4 (p-MAP4) impacts myocardial hypertrophy and ischemic heart failure. However, the detailed mechanism behind this remains under elucidated.
Yuesheng Huang +10 more
openaire +1 more source
Detecting Multiple Motif Co-occurrences in the Aarne-Thompson-Uther Tale Type Catalog: A Preliminary Survey [PDF]
, 2011 Catalogs project subject field experience onto a multidimensional map which is then converted to a hierarchical list. In the case of the Aarne-Thompson-Uther Tale Type Catalog (ATU), this subject field is the global pattern of tale content defining tale ...
Darányi, Sándor +4 more
core +2 more sources
Analysis of the native conformation of the LIR/AIM motif in the Atg8/LC3/GABARAP-binding proteins
, 2016 The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy).
Daniel J Klionsky (754614) +1 more
core +1 more source
Investigations of the molecular determinants of maize streak virus replication [PDF]
, 1999 Includes bibliographical references.Geminiviruses replicate via a rolling circle mechanism, which initiates at the origin of replication located within the long intergenic region (LIR).
Willment, Janet Anne
core +1 more source
Structure and Dynamics in the ATG8 Family From Experimental to Computational Techniques
Frontiers in Cell and Developmental Biology, 2020 Autophagy is a conserved and essential intracellular mechanism for the removal of damaged components. Since autophagy deregulation is linked to different kinds of pathologies, it is fundamental to gain knowledge on the fine molecular and structural ...
Valentina Sora +6 more
doaj +1 more source
Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants
Advanced Science, EarlyView.This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley +1 more source