Results 91 to 100 of about 8,390 (226)
Centromere Protein F in Tumor Biology: Cancer's Achilles Heel
Cancer Medicine, Volume 14, Issue 10, May 2025.ABSTRACT Background Centromere protein F (CENP‐F) is an important nuclear matrix protein that regulates mitosis and the cell cycle, and plays a crucial role in recruiting spindle checkpoint proteins to maintain the accuracy of chromosome segregation.
Zitong Wan +11 more
wiley +1 more source
Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders
Frontiers in Neuroscience, 2015 The Golgi apparatus is a dynamic organelle involved in processing and sorting of lipids and proteins. In neurons, the Golgi apparatus is important for the development of axons and dendrites and maintenance of their highly polarized morphology.
Dick eJaarsma, Casper eHoogenraad
doaj +1 more source
Magnetic field reversals in an experimental turbulent dynamo [PDF]
, 2007 We report the first experimental observation of reversals of a dynamo field generated in a laboratory experiment based on a turbulent flow of liquid sodium. The magnetic field randomly switches between two symmetric solutions B and -B.
Berhanu, M. +13 more
core +4 more sources
Studies of Recombinant TWA1 Reveal Constitutive Dimerization [PDF]
, 2017 The mammalian muskelin/RanBP9/C-terminal to LisH (CTLH) complex and the Saccharomyces cerevisiae glucose-induced degradation (GID) complex are large, multi-protein complexes that each contain a RING E3 ubiquitin ligase.
Adams, Jo +3 more
core +2 more sources
BicD and MAP7 Collaborate to Activate Homodimeric Drosophila Kinesin‐1 by Complementary Mechanisms
Traffic, Volume 26, Issue 4-6, April‐June 2025.Kinesin‐1 is auto‐inhibited and binds microtubules weakly. Binding of kinesin‐1 to the adaptor protein BicD enhances processive motion, while the microtubule‐associated protein MAP7 recruits more kinesin to the microtubule and enhances run length.
M. Yusuf Ali +4 more
wiley +1 more source
Emerging Trends of Nanotechnology towards Picotechnology: Energy and Biomolecules [PDF]
, 2010 In nature, metal oxide particles display their existence at the level of picomolecules in solution state and bioactive states in the body. We present evidence of picomolar behavior of molecules different than nanomolar behavior of particles.
Avdhesh Sharma +2 more
core +2 more sources
At the nucleus of cancer: how the nuclear envelope controls tumor progression
MedComm, Volume 6, Issue 2, February 2025.The review is focused on exploring novel intriguing perspectives on the role of the nuclear envelope in tumor progression. Alterations of nuclear envelope proteins result in the dysregulation of cellular pathways and promote tumorigenesis, highlighting that complex regulatory mechanisms lie behind the alterations in nuclear shape in cancer, thus ...
Francesca Paganelli +6 more
wiley +1 more source
Translational Psychiatry, 2021 Chronic mental illnesses (CMIs) pose a significant challenge to global health due to their complex and poorly understood etiologies and hence, absence of causal therapies.
Abhishek Cukkemane +8 more
doaj +1 more source
Nitrogen Isotopic Fractionation in Interstellar Ammonia [PDF]
, 2010 Using the Green Bank Telescope (GBT), we have obtained accurate measurements of the $^{14}$N/$^{15}$N isotopic ratio in ammonia in two nearby cold, dense molecular clouds, Barnard~1 and NGC 1333. The $^{14}$N/$^{15}$N ratio in Barnard~1, $334 \pm 50$ (3$\
Abbas +7 more
core +3 more sources
14‐3‐3ε conditional knockout mice exhibit defects in the development of the epidermis
FEBS Letters, Volume 598, Issue 24, Page 3005-3020, December 2024.A knockout of 14‐3‐3ε in the basal layer of the epidermis in mice leads to a decrease in proliferation and the thickness of the epidermis and decreased expression of differentiation markers. The knockout cells also show centrosome amplification, suggesting that centrosome amplification leads to decreased proliferation and subsequent thinning of the ...
Sarika Tilwani +2 more
wiley +1 more source