Results 61 to 70 of about 8,390 (226)
Teaming up: from motors to people. [PDF]
, 2013 When I reflect on how I became a cell biologist and why I love being one today, one thing that comes to mind is the many terrific collaborations I have had.
Reck-Peterson, Samara L
core +1 more source
eLife, 2020 Heterozygous loss of human PAFAH1B1 (coding for LIS1) results in the disruption of neurogenesis and neuronal migration via dysregulation of microtubule (MT) stability and dynein motor function/localization that alters mitotic spindle orientation ...
Hyang Mi Moon +3 more
doaj +1 more source
Lis1 puts mRNAs in their place [PDF]
Journal of Cell Biology, 2013 ![Figure][1] The apical accumulation of hairy RNA (green) is reduced in an embryo lacking Lis1 (bottom) compared with a control embryo (top). Nuclei are labeled red. A protein associated with the neurodevelopmental disorder lissencephaly promotes the assembly of dynein–dynactin ...
openaire +2 more sources
Cell Reports, 2018 Summary: Intracellular transport of membranous organelles and protein complexes to various destinations is fundamental to signaling transduction and cellular function.
Liansheng Liu +7 more
doaj +1 more source
Functional coupling of microtubules to membranes - implications for membrane structure and dynamics [PDF]
, 2012 The microtubule network dictates much of the spatial patterning of the cytoplasm, and the coupling of microtubules to membranes controls the structure and positioning of organelles and directs membrane trafficking between them.
Stephens, David J
core +2 more sources
Both doublecortin and doublecortin-like kinase play a role in cortical interneuron migration [PDF]
, 2007 Type I lissencephaly, a genetic disease characterized by disorganized cortical layers and gyral abnormalities, is associated with severe cognitive impairment and epilepsy.
Antypa, M +5 more
core +1 more source
A realistic assessment of methods for extracting gene/protein interactions from free text [PDF]
, 2009 Background: The automated extraction of gene and/or protein interactions from the literature is one of the most important targets of biomedical text mining research.
A Moschitti +32 more
core +4 more sources
Developmental downregulation of LIS1 expression limits axonal extension and allows axon pruning
Biology Open, 2017 The robust axonal growth and regenerative capacities of young neurons decrease substantially with age. This developmental downregulation of axonal growth may facilitate axonal pruning and neural circuit formation but limits functional recovery following ...
Kanako Kumamoto +5 more
doaj +1 more source
Reconstitution of dynein transport to the microtubule plus end by kinesin [PDF]
, 2014 Cytoplasmic dynein powers intracellular movement of cargo toward the microtubule minus end. The first step in a variety of dynein transport events is the targeting of dynein to the dynamic microtubule plus end, but the molecular mechanism underlying this
Goodman, Brian S +2 more
core +4 more sources
Locomotor hyperactivity in 14-3-3Zeta KO mice is associated with dopamine transporter dysfunction [PDF]
, 2013 Dopamine (DA) neurotransmission requires a complex series of enzymatic reactions that are tightly linked to catecholamine exocytosis and receptor interactions on pre- and postsynaptic neurons.
A Abi-Dargham +53 more
core +2 more sources