Results 91 to 100 of about 35,405 (287)

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids [PDF]

, 2017
Treatment of common bile duct disorders such as biliary atresia or ischaemic strictures is limited to liver transplantation or hepatojejunostomy due to the lack of suitable tissue for surgical reconstruction.
Alexander, Graeme J., Bargehr, Johannes, Berntsen, Natalie Lie, Bertero, Alessandro, Brown, Stephanie, Casey, John, Davies, Susan E., de Brito, Miguel Cardoso, Gelson, William T.H., Georgakopoulos, Nikitas, Gieseck, Richard L., Godfrey, Edmund M., Gómez-Vázquez, María J., Hannan, Nicholas R.F., Jensen, Kim B., Justin, Alexander W., Karlsen, Tom H., Madrigal, Pedro, Markaki, Athina E., Materek, Paulina M., Melum, Espen, Ortmann, Daniel, Pawlowski, Matthias, Pedersen, Marianne T., Pirmadjid, Negar, Rimland, Casey A., Ross, Alexander, Saeb-Parsy, Kourosh, Sampaziotis, Fotios, Sawiak, Stephen, Shu, Wenmiao, Simonic, Ingrid, Sinha, Sanjay, Skeldon, Gregor M., Snijders, Kirsten, Tysoe, Olivia C., Upponi, Sara S., Valestrand, Laura, Vallier, Ludovic, Wynn, Thomas A., Yiangou, Loukia, Zilbauer, Matthias, Zonneveld, Mariëlle C.F.   +42 more
core   +7 more sources

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Generation, Maintenance and HBV Infection of Human Liver Organoids [PDF]

, 2022
Shahla Romal, Tanvir Hossain, Tokameh Mahmoudi   +2 more
openalex   +1 more source

Organoids, organs-on-chips and other systems, and microbiota [PDF]

, 2017
The human gut microbiome is considered an organ in its entirety and has been the subject of extensive research due to its role in physiology, metabolism, digestion, and immune regulation.
Evans, Samantha, May, Stephanie, Parry, Lee   +2 more
core   +2 more sources

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]

, 2015
Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke, Alastair Watson, Andrew D Campbell, Ann Hedley, Aoife Maguire, Brendan Doyle, David J Huels, Fatih Ceteci, Fei Song, Gabriela Kalna, Guenievre Moreaux, James Matthews, Karen R Reed, Lee Parry, Lionel Larue, Marc Leushacke, Nick Barker, Ola Söderberg, Owen J Sansom, Rachel A Ridgway, Runjan Chetty, Serra S, Simon Leedham, Sorina Radulescu, Sparks AB, Stefano Serra, Sujata Biswas, Valerie S Meniel   +27 more
core   +2 more sources

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Development of Liver Cancer Organoids: Reproducing Tumor Microenvironment and Advancing Research for Liver Cancer Treatment

Technology in Cancer Research & Treatment
Liver cancer a leading cause of cancer-related deaths worldwide, yet understanding of its development mechanism remains limited, and treatment barriers present substantial challenges.
Kangkang Li MS, Kuiwu Ren MS, Sen Du BMed, Xiang Gao BMed, Jiangtao Yu MS   +4 more
doaj   +1 more source

Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids [PDF]

, 2023
Kristina Sæterdal Kømurcu, Ingrid Wilhelmsen, James L. Thorne, Stefan Krauß, Steven Ray Wilson, Aleksandra Aizenshtadt, Hanne Røberg‐Larsen   +6 more
openalex   +1 more source