Results 11 to 20 of about 124,419 (219)

FER Regulated by miR-206 Promotes Hepatocellular Carcinoma Progression via NF-κB Signaling

Frontiers in Oncology, 2021
ObjectivesFeline sarcoma-related protein (FER) is known to play a critical regulatory role in several carcinomas. However, the exact biological function of FER in hepatocellular carcinoma (HCC) still needs to be investigated.
Wenzhou Ding, Wenzhou Ding, Ye Fan, Ye Fan, Wenbo Jia, Wenbo Jia, Xiongxiong Pan, Guoyong Han, Guoyong Han, Yao Zhang, Yao Zhang, Zhiqiang Chen, Zhiqiang Chen, Yiwei Lu, Yiwei Lu, Jinyi Wang, Jinyi Wang, Jindao Wu, Jindao Wu, Xuehao Wang, Xuehao Wang   +20 more
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STK39 enhances the progression of Cholangiocarcinoma via PI3K/AKT pathway

iScience, 2021
Summary: Serine/threonine kinase 39 (STK39) is overexpressed in various tumor tissues and plays an essential role in tumor progression. In this study, we investigated the clinical value, as well as the potential functions and mechanisms of STK39 in ...
Xiaopei Hao, Yao Zhang, Yiwei Lu, Guoyong Han, Dawei Rong, Guoqiang Sun, Guangshun Sun, Weiwei Tang, Jindao Wu, Xuehao Wang   +9 more
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Development and Validation of a Novel Model to Predict Regional Lymph Node Metastasis in Patients With Hepatocellular Carcinoma

Frontiers in Oncology, 2022
BackgroundThe evaluation of the nodal status of hepatocellular carcinoma (HCC) is a classic but controversial topic. This study aimed to investigate the incidence of lymph node metastasis (LNM), explore the role of lymph node dissection (LND), and ...
Xiaoyuan Chen, Xiaoyuan Chen, Xiaoyuan Chen, Xiaoyuan Chen, Yiwei Lu, Yiwei Lu, Yiwei Lu, Xiaoli Shi, Xiaoli Shi, Xiaoli Shi, Xiaoli Shi, Guoyong Han, Guoyong Han, Guoyong Han, Jie Zhao, Jie Zhao, Jie Zhao, Jie Zhao, Yun Gao, Yun Gao, Yun Gao, Xuehao Wang, Xuehao Wang, Xuehao Wang, Xuehao Wang   +24 more
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Macrophage GSK3β-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy

Journal for ImmunoTherapy of Cancer, 2022
Background Glycogen synthase kinase 3β (GSK3β) was originally discovered to regulate glycogen synthesis and show a relationship to tumors. However, the biological functions of GSK3β in tumor-associated macrophages (TAMs) in cancers including ...
Li Liu, Jie Zhao, Jinyu Zhang, Guoqiang Sun, Yongxiang Xia, Xuehao Wang, Hanyuan Liu, Siqi Zhao, Zihao Zhang, Tian Huang, Xiangyi Kong, Weiwei Tang, Guangshun Sun, Hengsong Cao, Dawei Rong, Qinghua Ji   +15 more
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Epigenetics: Roles and therapeutic implications of non-coding RNA modifications in human cancers

Molecular Therapy: Nucleic Acids, 2021
As next-generation sequencing (NGS) is leaping forward, more than 160 covalent RNA modification processes have been reported, and they are widely present in every organism and overall RNA type.
Dawei Rong, Guangshun Sun, Fan Wu, Ye Cheng, Guoqiang Sun, Wei Jiang, Xiao Li, Yi Zhong, Liangliang Wu, Chuanyong Zhang, Weiwei Tang, Xuehao Wang   +11 more
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Long-term survival after anterior approach right hepatectomy combined with inferior vena cava thrombectomy using trans-diaphragmatic intrapericardial inferior vena cava occlusion: a case report and review of the literature

BMC Surgery, 2019
Background Presence of inferior vena cava tumor thrombosis (IVCTT) is an unfavorable factor to prognosis for patients with hepatocellular carcinoma (HCC). Case presentation Herein we report a case of HCC with IVC tumor thrombosis extending from the right
Yaodong Zhang, Zhengshan Wu, Ke Wang, Sheng Han, Changxian Li, Xiangcheng Li   +5 more
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Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3+ T Cell through Modulation of CD11b+ Cell Function

Journal of Immunology Research, 2018
Transfer of splenocytes isolated from B6 mice into normal B6D2F1 mice induces acute graft-versus-host disease (aGVHD), resulting in the expansion of donor cytotoxic T lymphocytes that eliminate recipient B cells. The cytokine IL-22, secreted by Th1 cells,
Jianbo Wu, Jian Gu, Shun Zhou, Hao Lu, Yunjie Lu, Ling Lu, Xuehao Wang   +6 more
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Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19+CD24hiCD27+ Breg Cells

Frontiers in Immunology, 2020
CD19+CD24hiCD27+ memory Breg cells exhibit decreased abundance in patients with chronic graft-versus-host disease (cGVHD) after liver transplantation and produce less IL-10 than those from patients without cGVHD and healthy donors.
Jinyang Li, Jinyang Li, Jinyang Li, Ji Gao, Ji Gao, Ji Gao, Haoming Zhou, Haoming Zhou, Haoming Zhou, Jinren Zhou, Jinren Zhou, Jinren Zhou, Zhenghua Deng, Zhenghua Deng, Zhenghua Deng, Yunjie Lu, Yunjie Lu, Yunjie Lu, Yunjie Lu, Jianhua Rao, Jianhua Rao, Jianhua Rao, Guwei Ji, Guwei Ji, Guwei Ji, Jian Gu, Jian Gu, Jian Gu, Xinxiang Yang, Xinxiang Yang, Xinxiang Yang, Yongxiang Xia, Yongxiang Xia, Yongxiang Xia, Xuehao Wang, Xuehao Wang, Xuehao Wang   +36 more
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PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells

Nature Communications, 2022
Members of the PRDI-BF1 and RIZ homology domain (PRDM) family have been involved in the regulation of several pathological conditions, including cancer.
Qing Li, Liren Zhang, Wenhua You, Jiali Xu, Jingjing Dai, Dongxu Hua, Ruizhi Zhang, Feifan Yao, Suiqing Zhou, Wei Huang, Yongjiu Dai, Yu Zhang, Tasiken Baheti, Xiaofeng Qian, Liyong Pu, Jing Xu, Yongxiang Xia, Chuanyong Zhang, Jinhai Tang, Xuehao Wang   +19 more
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PSMC2 Regulates Cell Cycle Progression Through the p21/Cyclin D1 Pathway and Predicts a Poor Prognosis in Human Hepatocellular Carcinoma

Frontiers in Oncology, 2021
Proteasome 26S subunit ATPase 2 (PSMC2) plays a pathogenic role in various cancers. However, its function and molecular mechanism in hepatocellular carcinoma (HCC) remain unknown.
Yiwei Liu, Yiwei Liu, Yiwei Liu, Hairong Chen, Xiangcheng Li, Xiangcheng Li, Xiangcheng Li, Feng Zhang, Feng Zhang, Feng Zhang, Lianbao Kong, Lianbao Kong, Lianbao Kong, Xuehao Wang, Xuehao Wang, Xuehao Wang, Jin Bai, Jin Bai, Xiaofeng Wu, Xiaofeng Wu, Xiaofeng Wu   +20 more
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