Results 11 to 20 of about 449,258 (311)
Over-Expression of GUSB Leads to Primary Resistance of Anti-PD1 Therapy in Hepatocellular Carcinoma
Frontiers in Immunology, 2022 Immunotherapy treatments, particularly immune checkpoint blockade, can result in benefits in clinical settings. But many pre-clinical and clinical studies have shown that resistance to anti-PD1 therapy frequently occurs, leading to tumor recurrence and ...
Xiangyi Kong +13 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundHepatocellular carcinoma (HCC) is a highly heterogeneous tumor with several rare pathological subtypes and which is still poorly understood. This study aimed to describe the epidemiological and clinical spectrum of five rare HCC subtypes and ...
Xiaoyuan Chen +30 more
doaj +1 more source
STK39 enhances the progression of Cholangiocarcinoma via PI3K/AKT pathway
iScience, 2021 Summary: Serine/threonine kinase 39 (STK39) is overexpressed in various tumor tissues and plays an essential role in tumor progression. In this study, we investigated the clinical value, as well as the potential functions and mechanisms of STK39 in ...
Xiaopei Hao +9 more
doaj +1 more source
Laparoscopic living donor hepatectomy [PDF]
Korean Journal of Hepato-Biliary-Pancreatic Surgery, 2012 Shortage of deceased donor organs led to establishment of living donor liver transplantation. Recent reports have strongly suggested that laparoscopic approach should be the gold standard for lesions in the left lateral section. Laparoscopic living donor left lateral sectionectomy was first described in 2002.
Kim, Ki-Hun +7 more
openaire +2 more sources
FER Regulated by miR-206 Promotes Hepatocellular Carcinoma Progression via NF-κB Signaling
Frontiers in Oncology, 2021 ObjectivesFeline sarcoma-related protein (FER) is known to play a critical regulatory role in several carcinomas. However, the exact biological function of FER in hepatocellular carcinoma (HCC) still needs to be investigated.
Wenzhou Ding +20 more
doaj +1 more source
Wide-Field Multi-Parameter FLIM: Long-Term Minimal Invasive Observation of Proteins in Living Cells. [PDF]
, 2011 Time-domain Fluorescence Lifetime Imaging Microscopy (FLIM) is a remarkable tool to monitor the dynamics of fluorophore-tagged protein domains inside living cells.
Duci, A. +9 more
core +5 more sources
Living donor liver transplantation [PDF]
HPB, 2006 The introduction of living donor liver transplantation (LDLT) has been one of the most remarkable steps in the field of liver transplantation (LT). First introduced for children in 1989, its adoption for adults has followed only 10 years later. As the demand for LT continues to increase, LDLT provides life-saving therapy for many patients who would ...
Nadalin, S. +5 more
openaire +2 more sources
Frontiers in Oncology, 2022 BackgroundThe evaluation of the nodal status of hepatocellular carcinoma (HCC) is a classic but controversial topic. This study aimed to investigate the incidence of lymph node metastasis (LNM), explore the role of lymph node dissection (LND), and ...
Xiaoyuan Chen +24 more
doaj +1 more source
Murine liver allograft transplantation: Tolerance and donor cell chimerism [PDF]
, 1994 Nonarterialized orthotopic liver transplantation with no immunosuppression was performed in 13 mouse‐strain combinations. Two strain combinations with major histocompatibility complex class I and class II and minor histocompatibility complex disparity ...
Arnold +45 more
core +1 more source
Journal for ImmunoTherapy of Cancer, 2022 Background Glycogen synthase kinase 3β (GSK3β) was originally discovered to regulate glycogen synthesis and show a relationship to tumors. However, the biological functions of GSK3β in tumor-associated macrophages (TAMs) in cancers including ...
Li Liu +15 more
doaj +1 more source