Frontiers in Immunology, 2018 The human host defense peptide LL-37 promotes immune activation such as induction of chemokine production and recruitment of leukocytes. Conversely, LL-37 also mediates anti-inflammatory responses such as production of anti-inflammatory cytokines, e.g ...
Mahadevappa Hemshekhar +4 more
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Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses. [PDF]
PLoS ONE, 2015 Human LL-37, a cationic antimicrobial peptide, was recently shown to have antiviral activity against influenza A virus (IAV) strains in vitro and in vivo.
Shweta Tripathi +5 more
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Microbiology Spectrum, 2023 Antimicrobial peptides play an important role in human innate defense against microbial pathogens. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides.
Sheng-Yuan Chen +2 more
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Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice [PDF]
, 2009 BACKGROUND: The worldwide appearance of drug-resistant strains of H. pylori motivates a search for new agents with therapeutic potential against this family of bacteria that colonizes the stomach, and is associated with adenocarcinoma development.
Andrzej Namiot +8 more
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New aspects of the structure and mode of action of the human cathelicidin LL-37 revealed by the intrinsic probe p-cyanophenylalanine [PDF]
, 2015 The human cathelicidin peptide LL-37 is an important effector of our innate immune system and contributes to host defence with direct antimicrobial activity and immunomodulatory properties, and by stimulating wound healing.
Morgera, Francesca +5 more
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Innate Immunity, 2020 Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice ...
Yumi Kumagai +5 more
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Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. [PDF]
PLoS ONE, 2015 Nontuberculous mycobacteria (NTM) are a large group of environmental organisms with worldwide distribution, but only a relatively few are known to be pathogenic.
Jennifer R Honda +8 more
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Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis [PDF]
, 2013 Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability.
Neregård, Petra
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Studies on Staphylococcus epidermidis biofilm formation and the bacterial interaction with the human cathelicidin antimicrobial peptide LL-37 [PDF]
, 2014 The long-term use of central venous catheters for delivering nutrients and drugs in preterm neonates has been related to nosocomial infections. The majority of late-onset sepsis in very preterm infants (
Hell, Eva
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Antimikrobielle Peptide in induziertem Sputum [PDF]
, 2006 Die COPD gilt bezüglich Klinik und Epidemiologie als die bedeutendste und gravierendste Langzeitkomplikation eines langjährigen Nikotinabusus. In der vorliegenden Arbeit wurde untersucht, ob diese Entzündung bereits bei jungen, klinisch noch gesunden ...
Bals, Robert (Dr. Dr.) +1 more
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