Results 41 to 50 of about 56,247,789 (275)

Sequence and the expression construct of SP-LL-37.

open access: yes, 2017
(A) Nucleotide sequence of SP-LL-37 containing the coding region and stop codon as well as the signal peptide (underlined). (B) Schematic diagram of the expression construct pSP1::SP-LL-37. Detection of Nos gene copy numbers in the T0 generation of pPZP::
Md. Amdadul Huq (3829780)   +6 more
core   +1 more source

LL-37 signaling increases CovS phosphatase activity.

open access: yes, 2018
(A) Representative Western blot (top) and bar representation (bottom) depicting CovR~P levels and (B) hasA transcript levels (means ± standard deviations, n = 4) of indicated GAS strains grown to mid-exponential phase in THY or THY supplemented with ...
Nicola Horstmann (201711)   +8 more
core   +1 more source

Glioblastoma Multiforme: Sensitivity to Antimicrobial Peptides LL-37 and PG-1, and Their Combination with Chemotherapy for Predicting the Overall Survival of Patients

open access: yesPharmaceutics
Background/Objectives: Glioblastomas (GBMs) are the most malignant and intractable of all cancers, with an unfavorable clinical prognosis for affected patients. The objective was to analyze the sensitivity of GBM cells to the antimicrobial peptides (AMPs)
Alexander N. Chernov   +9 more
doaj   +1 more source

The Role of Antimicrobial Peptides in Influenza Virus Infection and Their Potential as Antiviral and Immunomodulatory Therapy

open access: yesPharmaceuticals, 2016
Influenza A virus (IAV) remains a major threat that can cause severe morbidity and mortality due to rapid genomic variation. Resistance of IAVs to current anti-IAV drugs has been emerging, and antimicrobial peptides (AMPs) have been considered to be ...
I-Ni Hsieh, Kevan L. Hartshorn
doaj   +1 more source

Identification of pPZP::SP-LL-37 insertion transgenic plants.

open access: yes, 2017
The genomic structures of insertion alleles were determined by FST analysis in which boxes, bold lines, and triangles indicate exons, intron, and pPZP::SP-LL-37, respectively.
Md. Amdadul Huq (3829780)   +6 more
core   +1 more source

Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses. [PDF]

open access: yesPLoS ONE, 2015
Human LL-37, a cationic antimicrobial peptide, was recently shown to have antiviral activity against influenza A virus (IAV) strains in vitro and in vivo.
Shweta Tripathi   +5 more
doaj   +1 more source

Subcellular localization of the SP-LL-37 protein in tobacco.

open access: yes, 2017
GFP protein was attached to the end of C-terminal of LL-37 protein to see the localization in tobacco cells. (A) Cartoon image of constructs used in subcellular localization. (B) Fluorescence image of cell membrane (N.
Md. Amdadul Huq (3829780)   +6 more
core   +1 more source

Host Defense Peptide LL-37-Mediated Chemoattractant Properties, but Not Anti-Inflammatory Cytokine IL-1RA Production, Is Selectively Controlled by Cdc42 Rho GTPase via G Protein-Coupled Receptors and JNK Mitogen-Activated Protein Kinase

open access: yesFrontiers in Immunology, 2018
The human host defense peptide LL-37 promotes immune activation such as induction of chemokine production and recruitment of leukocytes. Conversely, LL-37 also mediates anti-inflammatory responses such as production of anti-inflammatory cytokines, e.g ...
Mahadevappa Hemshekhar   +4 more
doaj   +1 more source

Antimicrobial peptide LL-37 disrupts plasma membrane and calcium homeostasis in Candida albicans via the Rim101 pathway

open access: yesMicrobiology Spectrum, 2023
Antimicrobial peptides play an important role in human innate defense against microbial pathogens. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides.
Sheng-Yuan Chen   +2 more
doaj   +1 more source

Generation and molecular analysis of the transgenic lines expressing pPZP::SP-LL-37.

open access: yes, 2017
(A) TaqMan PCR analysis for copy number assays using TaqMan probe for selected homozygous T1 plants; T2 homo; T2-homozygous, T2 hetero; T2-heterozygous, NT; no template, WT; wild type, 6–1~20–3; 19 T1 plants.
Md. Amdadul Huq (3829780)   +6 more
core   +1 more source

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