Results 51 to 60 of about 1,333,743 (274)

Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils

open access: yesInnate Immunity, 2020
Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice ...
Yumi Kumagai   +5 more
doaj   +1 more source

Antimicrobial peptide LL-37 disrupts plasma membrane and calcium homeostasis in Candida albicans via the Rim101 pathway

open access: yesMicrobiology Spectrum, 2023
Antimicrobial peptides play an important role in human innate defense against microbial pathogens. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides.
Sheng-Yuan Chen   +2 more
doaj   +1 more source

Subcellular localization of the SP-LL-37 protein in tobacco.

open access: yes, 2017
GFP protein was attached to the end of C-terminal of LL-37 protein to see the localization in tobacco cells. (A) Cartoon image of constructs used in subcellular localization. (B) Fluorescence image of cell membrane (N.
Md. Amdadul Huq (3829780)   +6 more
core   +1 more source

LL-37 induced HA metabolism and inflammatory cytokines and mediators.

open access: yes, 2019
(A) SW982 cells were treated with varied concentrations of LL-37 for 72 hr. Culture media were collected and measured for HA concentrations. (B-H) SW982 cells were treated with 12.5 ng/mL of LL-37 for varied times.
Nutnicha Sirikaew (6900452)   +6 more
core   +1 more source

Evaluation of Cathelicidin (LL-37) Serum Levels Among Iraqi Psoriatic Patients and Its Association with Disease Severity and Complications

open access: yesمجلة الكوفة الطبية
Background: Psoriasis is a chronic skin condition distinguished by inflammation and the rapid proliferation of skin cells, leading to scaly, red patches.
Rasool Moussa Bader Al-asade   +1 more
doaj   +1 more source

Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. [PDF]

open access: yesPLoS ONE, 2015
Nontuberculous mycobacteria (NTM) are a large group of environmental organisms with worldwide distribution, but only a relatively few are known to be pathogenic.
Jennifer R Honda   +8 more
doaj   +1 more source

Generation and molecular analysis of the transgenic lines expressing pPZP::SP-LL-37.

open access: yes, 2017
(A) TaqMan PCR analysis for copy number assays using TaqMan probe for selected homozygous T1 plants; T2 homo; T2-homozygous, T2 hetero; T2-heterozygous, NT; no template, WT; wild type, 6–1~20–3; 19 T1 plants.
Md. Amdadul Huq (3829780)   +6 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The di-leucine motif in the host defense peptide LL-37 is essential for initiation of autophagy in human macrophages

open access: yesCell Reports
Summary: The human cathelicidin peptide LL-37 induces autophagy in human macrophages. Different post-translational modifications (PTMs) such as citrullination, acetylation, and formylation impact LL-37, yet their effect on autophagy remains unknown. Thus,
Rokeya Sultana Rekha   +8 more
doaj   +1 more source

LL-37 induces activation of caspase-1 during airway epithelial cell infection with P. aeruginosa.

open access: yes, 2019
A) FLICA Caspase 1 activation assay quantitation in NHBE cells, assessed by fluorescence microscopy, 3 hours post-treatment with either media only (control), 20 μg/ml LL-37, PAO1 at 10:1 MOI, PAO1 + LL-37, 10 ng/ml LPS for 3 hours, 5 mM ATP only for 1 ...
Hsin-Ni Li (6585674)   +12 more
core   +1 more source

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