Results 51 to 60 of about 191,557 (278)
Frontiers in Immunology, 2018 The human host defense peptide LL-37 promotes immune activation such as induction of chemokine production and recruitment of leukocytes. Conversely, LL-37 also mediates anti-inflammatory responses such as production of anti-inflammatory cytokines, e.g ...
Mahadevappa Hemshekhar +4 more
doaj +1 more source
Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses. [PDF]
PLoS ONE, 2015 Human LL-37, a cationic antimicrobial peptide, was recently shown to have antiviral activity against influenza A virus (IAV) strains in vitro and in vivo.
Shweta Tripathi +5 more
doaj +1 more source
Cationic Peptides Facilitate Iron-induced Mutagenesis in Bacteria [PDF]
, 2015 Pseudomonas aeruginosa is the causative agent of chronic respiratory infections and is an important pathogen of cystic fibrosis patients. Adaptive mutations play an essential role for antimicrobial resistance and persistence.
Makarova, Olga +3 more
core +3 more sources
Microbiology Spectrum, 2023 Antimicrobial peptides play an important role in human innate defense against microbial pathogens. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides.
Sheng-Yuan Chen +2 more
doaj +1 more source
Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial [PDF]
, 2012 BACKGROUND: Treatment of shigellosis in rabbits with butyrate reduces clinical severity and counteracts the downregulation of cathelicidin (CAP-18) in the large intestinal epithelia.
Abu Saleh Mohammed Arifuzzaman +9 more
core +1 more source
Innate Immunity, 2020 Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice ...
Yumi Kumagai +5 more
doaj +1 more source
Studies on the therapeutic modulation of inflammation in the synovial membrane of rheumatoid arthritis [PDF]
, 2013 Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the synovial membrane that can lead to joint deformity and physical disability.
Neregård, Petra
core +1 more source
Pharmaceuticals, 2016 Influenza A virus (IAV) remains a major threat that can cause severe morbidity and mortality due to rapid genomic variation. Resistance of IAVs to current anti-IAV drugs has been emerging, and antimicrobial peptides (AMPs) have been considered to be ...
I-Ni Hsieh, Kevan L. Hartshorn
doaj +1 more source
Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. [PDF]
PLoS ONE, 2015 Nontuberculous mycobacteria (NTM) are a large group of environmental organisms with worldwide distribution, but only a relatively few are known to be pathogenic.
Jennifer R Honda +8 more
doaj +1 more source
The GraRS regulatory system controls susceptibility to antimicrobial host defenses [PDF]
, 2008 Background Modification of teichoic acids with D-alanine by the products of the dlt operon protects Gram-positive bacteria against major antimicrobial host defense molecules such as defensins, cathelicidins, myeloperoxidase or phospholipase.
Nizet Victor +6 more
core +2 more sources