Results 51 to 60 of about 1,333,743 (274)
Sepsis is a life-threatening disease caused by systemic dys-regulated inflammatory response to infection. We previously revealed that LL-37, a human cathelicidin antimicrobial peptide, improves the survival of cecal ligation and puncture septic mice ...
Yumi Kumagai +5 more
doaj +1 more source
Antimicrobial peptides play an important role in human innate defense against microbial pathogens. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides.
Sheng-Yuan Chen +2 more
doaj +1 more source
Subcellular localization of the SP-LL-37 protein in tobacco.
GFP protein was attached to the end of C-terminal of LL-37 protein to see the localization in tobacco cells. (A) Cartoon image of constructs used in subcellular localization. (B) Fluorescence image of cell membrane (N.
Md. Amdadul Huq (3829780) +6 more
core +1 more source
LL-37 induced HA metabolism and inflammatory cytokines and mediators.
(A) SW982 cells were treated with varied concentrations of LL-37 for 72 hr. Culture media were collected and measured for HA concentrations. (B-H) SW982 cells were treated with 12.5 ng/mL of LL-37 for varied times.
Nutnicha Sirikaew (6900452) +6 more
core +1 more source
Background: Psoriasis is a chronic skin condition distinguished by inflammation and the rapid proliferation of skin cells, leading to scaly, red patches.
Rasool Moussa Bader Al-asade +1 more
doaj +1 more source
Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. [PDF]
Nontuberculous mycobacteria (NTM) are a large group of environmental organisms with worldwide distribution, but only a relatively few are known to be pathogenic.
Jennifer R Honda +8 more
doaj +1 more source
Generation and molecular analysis of the transgenic lines expressing pPZP::SP-LL-37.
(A) TaqMan PCR analysis for copy number assays using TaqMan probe for selected homozygous T1 plants; T2 homo; T2-homozygous, T2 hetero; T2-heterozygous, NT; no template, WT; wild type, 6–1~20–3; 19 T1 plants.
Md. Amdadul Huq (3829780) +6 more
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Summary: The human cathelicidin peptide LL-37 induces autophagy in human macrophages. Different post-translational modifications (PTMs) such as citrullination, acetylation, and formylation impact LL-37, yet their effect on autophagy remains unknown. Thus,
Rokeya Sultana Rekha +8 more
doaj +1 more source
LL-37 induces activation of caspase-1 during airway epithelial cell infection with P. aeruginosa.
A) FLICA Caspase 1 activation assay quantitation in NHBE cells, assessed by fluorescence microscopy, 3 hours post-treatment with either media only (control), 20 μg/ml LL-37, PAO1 at 10:1 MOI, PAO1 + LL-37, 10 ng/ml LPS for 3 hours, 5 mM ATP only for 1 ...
Hsin-Ni Li (6585674) +12 more
core +1 more source

