Results 81 to 90 of about 1,333,743 (274)
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Cathelicidins—Therapeutic antimicrobial and antitumor host defense peptides for oral diseases
Japanese Dental Science Review, 2011 The oral epithelium functions as a mechanical and protective barrier to resist bacterial infection. Several types of host defense peptides (HDPs), including defensins, cathelicidins, and histatins, may have important roles in innate host defense.
Kazuhiko Okumura
doaj +1 more source
Flanking T-DNA analysis from pPZP::SP-LL-37 T0 plants.
, 2017 Flanking T-DNA analysis from pPZP::SP-LL-37 T0 plants.
Md. Amdadul Huq (3829780) +6 more
core +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King +10 more
wiley +1 more source
Association of vitamin D3, VDR gene polymorphisms, and LL-37 with a clinical form of Chagas Disease
Revista da Sociedade Brasileira de Medicina TropicalINTRODUCTION: Chagas disease (CD) is an important public health problem in Brazil and worldwide. Aging and obesity are important matters in patients with CD, as is hypovitaminosis D3, which can decrease the quality of life of these patients ...
Luiz Roberto de Oliveira Junior +5 more
doaj +1 more source
, 2019 NHBE cells were exposed for 3 hours to media only (control), 20 μg/ml LL-37 only, PAO1/ heat killed PAO1/ P. aeruginosa strain T3SS at 10:1 MOI +/- 20 μg/ml LL-37, or PAO1 supernatant +/- 20 μg/ml LL-37.
Hsin-Ni Li (6585674) +12 more
core +1 more source
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Arthritis Care &Research, EarlyView.Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source
OmpA Binding Mediates the Effect of Antimicrobial Peptide LL-37 on Acinetobacter baumannii. [PDF]
PLoS ONE, 2015 Multidrug-resistant Acinetobacter baumannii has recently emerged as an important pathogen in nosocomial infection; thus, effective antimicrobial regimens are urgently needed.
Ming-Feng Lin +4 more
doaj +1 more source
, 2019 A) Representative examples of neutrophil migration assayed in ChemoTx chambers. Human neutrophils were assayed migrating towards chambers containing filtered conditioned supernatant from NHBE cells treated for 3 hours with media only (untreated control),
Hsin-Ni Li (6585674) +12 more
core +1 more source