Results 91 to 100 of about 5,087 (193)

Human Leukocyte Antigen (HLA) and Tumor Immunity: A Critical Link in Cancer Immunotherapy

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Malignant tumors pose a serious threat to human health and survival, with profound economic consequences worldwide. Human leukocyte antigens (HLAs), encoded by the human major histocompatibility complex, represent one of the most polymorphic genetic systems and play a vital role in immune regulation.
Donath Damian
wiley   +1 more source

LMP2 expression and proteasome activity in NOD mice [PDF]

Nature Medicine, 2000
H A, Runnels, W A, Watkins, J J, Monaco
openaire   +6 more sources

Targeted Therapy for Idiopathic Inflammatory Myopathy

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune disorders characterized by chronic muscle inflammation and significant extramuscular involvement. A substantial proportion of patients exhibit refractory or relapsing disease despite conventional immunosuppressive therapies, necessitating the ...
Ruijie Wang, Wei Lin, Qibing Xie, Geng Yin   +3 more
wiley   +1 more source

Web of Science‐Based Visualization of Mapping Global Scientific Production on Epstein–Barr Virus‐Associated Autoimmune Diseases: A Bibliometric Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Epstein–Barr virus (EBV) has been implicated in autoimmune diseases (AIDs), yet a comprehensive analysis of global research trends, knowledge gaps, and translational opportunities remains lacking. Therefore, we aimed to study the research output of EBV‐associated AIDs globally.
Binbin Yu, Baofang Wu, Jian Wang, Shaojie Li, Chunnuan Chen, Zhenlong Liu, Hongzhi Gao   +6 more
wiley   +1 more source

Immune reconstitution of HLA-A*0201/BMLF1- and HLA-A*1101/LMP2-specific Epstein Barr virus cytotoxic T lymphocytes within 90 days after haploidentical hematopoietic stem cell transplantation

Virology Journal, 2019
Background Haploidentical hematopoietic stem cell transplant (haplo-HSCT) recipients are at high risk for Epstein Barr virus (EBV)-related diseases. EBV-specific CD8+ cytotoxic T cells can control EBV-infected B cell expansion; however, no studies have ...
Ling Zhou, Dao-pei Lu
doaj   +1 more source

Differences in Epstein-Barr Virus Characteristics and Viral-Related Microenvironment Could Be Responsible for Lymphomagenesis in Children

Pathogens, 2020
In Argentina, Epstein-Barr virus (EBV) presence is associated with Hodgkin lymphoma (HL) in patients younger than 10 years, suggesting a relationship between low age of EBV infection and HL.
Aldana Vistarop, Oscar Jimenez, Melina Cohen, Elena De Matteo, Maria Victoria Preciado, Paola Chabay   +5 more
doaj   +1 more source

Novel Immunotherapy Options for Extranodal NK/T-Cell Lymphoma

Frontiers in Oncology, 2018
Extranodal NK/T-cell lymphoma (ENKTCL) is a highly aggressive mature NK/T-cell neoplasm marked by NK-cell phenotypic expression of CD3ε and CD56. While the disease is reported worldwide, there is a significant geographic variation with its highest ...
Boyu Hu, Yasuhiro Oki
doaj   +1 more source

Inhibition of Immunoproteasome Attenuates NLRP3 Inflammasome Response by Regulating E3 Ubiquitin Ligase TRIM31

Cells
Excessive secretion of pro-inflammatory cytokines leads to the disruption of intestinal barrier in inflammatory bowel disease (IBD). The inflammatory cytokine tumor necrosis factor alpha (TNFα) induces the assembly of the NLRP3 inflammasome, resulting in
Yubin Lee, Boran Yoon, Sumin Son, Eunbin Cho, Kyung Bo Kim, Eun Young Choi, Dong-Eun Kim   +6 more
doaj   +1 more source

Analysis of a structured intronic region of the LMP2 pre-mRNA from EBV reveals associations with human regulatory proteins and nuclear actin

BMC Research Notes, 2019
Objective The pre-mRNA of the Epstein–Barr virus LMP2 (latent membrane protein 2) has a region of unusual RNA structure that partially spans two consecutive exons and the entire intervening intron; suggesting RNA folding might affect splicing ...
Nuwanthika Kumarasinghe, Walter N. Moss
doaj   +1 more source

Nomenclature for Factors of the HLA System, 2026

HLA, Volume 107, Issue 3, March 2026.
Steven G. E. Marsh, Kazutoyo Osoegawa, Walter F. Bodmer, Ronald E. Bontrop, Mary N. Carrington, Henry A. Erlich, Sebastiaan Heidt, Rhonda Holdsworth, Wolfgang R. Mayr, Martin Maiers, Peter Parham, Effie W. Petersdorf, James Robinson, John Trowsdale, Marcelo Fernández‐Viña   +14 more
wiley   +1 more source