Results 121 to 130 of about 5,087 (193)

Molecular Basis of the Selectivity of the Immunoproteasome Catalytic Subunit LMP2-Specific Inhibitor Revealed by Molecular Modeling and Dynamics Simulations

, 2016
Given that immunoproteasome inhibitors are currently being developed for a variety of potent therapeutic purposes, the unique specificity of an α′,β′-epoxyketone peptide (UK101) toward the LMP2 subunit of the immunoproteasome (analogous to β5 subunit of ...
Mohamed Diwan M. Abdul Hameed (2263156), Xiao-Jun Yao (842020), Marie Wehenkel (2263159), Beilei Lei (449125), Jennifer L. Muzyka (1535959), Kyung-Bo Kim (2106733), Adel Hamza (471950), Chang-Guo Zhan (147266)   +7 more
core   +1 more source

A Linear-Scaling Integral-Direct Explicitly Correlated Second-Order Møller-Plesset Approach. [PDF]

J Chem Theory Comput
Kállay M, Nagy PR, Ladóczki B, Mester D.   +3 more
europepmc   +1 more source

The immunoproteasome as a neuroimmune hub in the central nervous system: from proteostasis stress to inflammatory pathology. [PDF]

J Neuroinflammation
Zhao H, Liu Y, Chen X.
europepmc   +1 more source

Epstein-Barr virus associated diseases: Immune alterations and targeted approaches. [PDF]

Front Immunol
Cao S, Xiong J, Zhao J, Zhao WL.
europepmc   +1 more source

Toward a thermodynamic stability order of the phosphorus allotropes. [PDF]

RSC Adv
Bonometti L, Sansone G, Rivera-Almazo M, Usvyat D, Karttunen AJ, Maschio L.   +5 more
europepmc   +1 more source

Inhibition of Proteasome LMP2 Activity Suppresses Chil3 Expression in Mouse Colon Adenocarcinoma Tissue and Restrains Tumor Growth. [PDF]

Oncol Res
Astakhova TM, Karpov NS, Dashenkova NO, Alpeeva EV, Nesterchuk MV, Akopov SB, Mikaelyan AS, Ryabchenko AS, Erokhov PA, Sharova NP.   +9 more
europepmc   +1 more source

Therapeutic Vaccines for Head and Neck Squamous Cell Carcinoma and Nasopharyngeal Carcinoma. [PDF]

Vaccines (Basel)
Baliton M, Alfatlawi D, Attarian S, Nabar R, Villaflor V.   +4 more
europepmc   +1 more source

Immunoproteasomes in Skeletal Muscle Pathologies: Emerging Roles, Conflicting Evidence, and Future Directions. [PDF]

Cells
Kalinkovich A, Livshits G.
europepmc   +1 more source

CD5 ablation enhances persistence and antitumor potency of engineered T cells by mitigating exhaustion and promoting cytotoxicity. [PDF]

J Immunother Cancer
Wu J, Cheng J, Zhu L, Gao Q, Lin H, Zeng Y, Li Y, Li W, An N, Huang L, Xiao M, Li D, Mu W.   +12 more
europepmc   +1 more source

Epstein-Barr virus: biology, pathogenesis and therapy of lymphomas. [PDF]

Discov Oncol
Chen J, Zhang S, Zhao Y, Zheng F, Cheng F.   +4 more
europepmc   +1 more source