Results 41 to 50 of about 4,413 (167)
PLoS ONE, 2010 BackgroundAlbeit several studies pointed out the pivotal role that CD4+T cells have in Multiple Sclerosis, the CD8+ T cells involvement in the pathology is still in its early phases of investigation.
Michele Mishto +22 more
doaj +1 more source
The effect of Epstein-Barr virus Latent Membrane Protein 2 expression on the kinetics of early B cell infection. [PDF]
PLoS ONE, 2013 Infection of human B cells with wild-type Epstein-Barr virus (EBV) in vitro leads to activation and proliferation that result in efficient production of lymphoblastoid cell lines (LCLs). Latent Membrane Protein 2 (LMP2) is expressed early after infection
Laura R Wasil +3 more
doaj +1 more source
Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases
Frontiers in Immunology, 2021 Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated in the etiology of multiple lymphoid and epithelial cancers.
Xinle Cui +3 more
doaj +1 more source
Indonesian Journal of Cancer, 2009 Kanker nasofaring (NPC) biasa ditemukan di Indonesia dan berkaitan dengan penyakit tingkat lanjut (advanced disease). Keberadaan virus Epstein-Bar deoxyribonucleic acid (EBV-DNA) sudah lama ditawarkan untuk deteksi awal terhadap kegagalan jarak (distant ...
Dewi Soeis Marzaini +2 more
doaj +1 more source
The Epstein Barr virus circRNAome. [PDF]
PLoS Pathogens, 2018 Our appreciation for the extent of Epstein Barr virus (EBV) transcriptome complexity continues to grow through findings of EBV encoded microRNAs, new long non-coding RNAs as well as the more recent discovery of over a hundred new polyadenylated lytic ...
Nathan Ungerleider +14 more
doaj +1 more source
On the Role of the Immunoproteasome in Protein Homeostasis
Cells, 2021 Numerous cellular processes are controlled by the proteasome, a multicatalytic protease in the cytosol and nucleus of all eukaryotic cells, through regulated protein degradation.
Michael Basler, Marcus Groettrup
doaj +1 more source
Small, Volume 22, Issue 49, 1 September 2026.Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley +1 more source
Scientific Reports, 2021 Epstein-Barr virus (EBV) has been recently found to generate novel circular RNAs (circRNAs) through backsplicing. However, comprehensive catalogs of EBV circRNAs in other cell lines and their functional characterization are still lacking.
Ke-En Tan +13 more
doaj +1 more source
LMP2-Specific Inhibitors: Chemical Genetic Tools for Proteasome Biology
Chemistry & Biology, 2007 The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. However, its other pathophysiological functions are still not very well understood.
Ho, Yik Khuan (Abby) +4 more
openaire +2 more sources
LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes [PDF]
Current Biology, 1995 Major histocompatibility complex (MHC) class I molecules present short peptides generated by intracellular protein degradation to cytotoxic T lymphocytes (CTL). The multisubunit, non-lysosomal proteinases known as proteasomes have been implicated in the generation of these peptides.
Sibille, Catherine +7 more
openaire +4 more sources