Results 51 to 60 of about 5,087 (193)

The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis

Frontiers in Immunology, 2021
Cell survival and function critically relies on the fine-tuned balance of protein synthesis and degradation. In the steady state, the standard proteasome is sufficient to maintain this proteostasis.
Timothy French, Nicole Israel, Nicole Israel, Henning Peter Düsedau, Anne Tersteegen, Johannes Steffen, Clemens Cammann, Clemens Cammann, Eylin Topfstedt, Daniela Dieterich, Daniela Dieterich, Thomas Schüler, Ulrike Seifert, Ulrike Seifert, Ildiko Rita Dunay, Ildiko Rita Dunay   +15 more
doaj   +1 more source

Evaluation of Epstein-Barr Virus Latent Membrane Protein 2 Specific T-Cell Receptors Driven by T-Cell Specific Promoters Using Lentiviral Vector

Clinical and Developmental Immunology, 2011
Transduction of latent membrane protein 2 (LMP2)-specific T-cell receptors into activated T lymphocytes may provide a universal, MHC-restricted mean to treat EBV-associated tumors in adoptive immunotherapy.
Dongchang Yang, Qing Shao, Hua Sun, Xiaoxin Mu, Yun Gao, Runqiu Jiang, Jiajie Hou, Kun Yao, Yun Chen, Beicheng Sun   +9 more
doaj   +1 more source

The Accuracy of Plasma EBV-DNA Quantification Using LMP2 as Primer to Detect Distance Metastasis After Radiation of Nasopharyngeal Cancer in Dharmais National Cancer Center

Indonesian Journal of Cancer, 2009
Nasopharyngeal carcinoma (NPC) is common in Indonesia and is associated with advanced disease. The presence of Epstein-Bar virus deoxyribonucleic acid (EBV-DNA0 has been proposed for early detection of distant failure after radiation therapy.
Dewi Soeis Marzaini, Demak L. Tobing, Siti Boedina Kresno, Soehartati Gundhowiardjo   +3 more
doaj   +1 more source

The effect of Epstein-Barr virus Latent Membrane Protein 2 expression on the kinetics of early B cell infection. [PDF]

PLoS ONE, 2013
Infection of human B cells with wild-type Epstein-Barr virus (EBV) in vitro leads to activation and proliferation that result in efficient production of lymphoblastoid cell lines (LCLs). Latent Membrane Protein 2 (LMP2) is expressed early after infection
Laura R Wasil, Monica J Tomaszewski, Aki Hoji, David T Rowe   +3 more
doaj   +1 more source

Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases

Frontiers in Immunology, 2021
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated in the etiology of multiple lymphoid and epithelial cancers.
Xinle Cui, Xinle Cui, Clifford M. Snapper, Clifford M. Snapper   +3 more
doaj   +1 more source

Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population.

PLoS ONE, 2010
BackgroundAlbeit several studies pointed out the pivotal role that CD4+T cells have in Multiple Sclerosis, the CD8+ T cells involvement in the pathology is still in its early phases of investigation.
Michele Mishto, Elena Bellavista, Claudia Ligorio, Kathrin Textoris-Taube, Aurelia Santoro, Mara Giordano, Sandra D'Alfonso, Florinda Listì, Benedetta Nacmias, Elena Cellini, Maurizio Leone, Luigi M E Grimaldi, Chiara Fenoglio, Federica Esposito, Filippo Martinelli-Boneschi, Daniela Galimberti, Elio Scarpini, Ulrike Seifert, Maria Pia Amato, Calogero Caruso, Maria P Foschini, Peter M Kloetzel, Claudio Franceschi   +22 more
doaj   +1 more source

LMP1 and LMP2 IF co-staining in oral epithelial cells.

, 2013
(A–D) Detection of LMP2 and LMP1 by IF double staining in oral epithelial cells, LMP2 (green, upper left), LMP1 (red, upper right), DAPI (blue, below left), merge (below right).
Sébastien Vitale (499643), Caroline C. Mouline (499644), Patrick Mahler (499647), Séverine Vincent-Bugnas (499642), Wafa Khaali (499645), Alain Doglio (499650), Yves Charbit (499646), Janet L. Maryanski (499649), Paul Hofman (103032), Isabelle Prêcheur (499648)   +9 more
core   +1 more source

Regulación de la expresión de los genes "tap1" y "lmp2" [PDF]

, 2002
El procesamiento y la presentación de antígenos es un mecanismo clave en el desarrollo de la respuesta inmunitaria. En el presente trabajo, se ha estudiado la regulación de los genes tap1 y lmp2.
Marquès Soler, Laura
core   +1 more source

The Epstein Barr virus circRNAome. [PDF]

PLoS Pathogens, 2018
Our appreciation for the extent of Epstein Barr virus (EBV) transcriptome complexity continues to grow through findings of EBV encoded microRNAs, new long non-coding RNAs as well as the more recent discovery of over a hundred new polyadenylated lytic ...
Nathan Ungerleider, Monica Concha, Zhen Lin, Claire Roberts, Xia Wang, Subing Cao, Melody Baddoo, Walter N Moss, Yi Yu, Michael Seddon, Terri Lehman, Scott Tibbetts, Rolf Renne, Yan Dong, Erik K Flemington   +14 more
doaj   +1 more source

Extranodal natural killer/T‐cell lymphoma: From fatal to curable

CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong, Yok‐Lam Kwong, Laurence de Leval, Shu‐Nan Qi, Choon Kiat Ong, Philippe Gaulard, Arnaud Jaccard, Steven M. Horwitz, Ye‐Xiong Li, Sai‐Juan Chen, Ritsuro Suzuki, Won Seog Kim, Wei‐Li Zhao   +12 more
wiley   +1 more source