Results 21 to 30 of about 33,716 (178)

LncRNA XIST facilitates the odontogenic differentiation of dental pulp stem cells via the FUS/ZBTB16 [PDF]

Journal of Applied Oral Science
Objective This study aims to explore the regulatory mechanism of long noncoding RNA X inactive specific transcript (lncRNA XIST) in the odontogenic differentiation of human dental pulp stem cells (hDPSCs).
Ruiqing CHENG, Honglei SUN, Xiaotong QIAO, Xuefang CHEN   +3 more
doaj   +2 more sources

LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

Cancer Cell International, 2018
Background The abnormal expression of non-coding RNAs (ncRNAs), such as microRNAs and long ncRNAs, often contribute to the development of cancers.
Ran Xu, Xuan Zhu, Fangzhi Chen, Changkun Huang, Kai Ai, Hongtao Wu, Lei Zhang, Xiaokun Zhao   +7 more
doaj   +2 more sources

Prognostic role of long non-coding RNA XIST expression in patients with solid tumors: a meta-analysis

Cancer Cell International, 2018
Background The aberrant expression of long non-coding RNA (lncRNA) X inactivate-specific transcript (XIST) has been demonstrated to be involved in the tumourigenesis and the development of various cancers.
Huihui Mao, Kai Wang, Yuehua Feng, Jun Zhang, Lili Pan, Yuxia Zhan, Haijun Sheng, Guanghua Luo   +7 more
doaj   +2 more sources

Identification and functional analysis of LncRNA-XIST ceRNA network in prostate cancer. [PDF]

BMC Cancer, 2022
Abstract Background Long non-coding RNAs (lncRNAs) play a functional role in the progression of prostate cancer (PCa). However, the molecular mechanism, expression, or function of the lncRNA XIST in PCa is not well understood. Therefore, the major goal of this study was to investigate the involvement of XIST in PCa.
Wang J, Huang J, Guo Y, Fu Y, Cao Y, Zhou K, Ma J, Lv B, Huang W.   +8 more
europepmc   +4 more sources

The impact of the expression signatures of LncRNAs HBBP1 and XIST on the diagnostic significance of patients with β-Thalassemia

Annals of Hematology
β-thalassemia is an inherited blood disorder with long-term associated complications. The purpose of this study was to evaluate the clinical significance of the lncRNA-HBBP1 and lncRNA-XIST expression profiles in the diagnosis of β-thalassemia patients ...
Abdallah M. Gameel, Shimaa Abdelsattar, Zeinab A. Kasemy, Mai El-Sayad Abd El-Hamid, Eman Masoud Abd ElGayed, Basma M. Abdelgawed, Amira Fathy El-Fiky, Mariam E. Labib, Sabry M. Abdelmageed, Mahmoud Ahmed El Hawy, Yasmin Mohsen, Hanan M. Bedair   +11 more
doaj   +3 more sources

Functional dissection of the Xist lncRNA conserved sequences in X-chromosome inactivation

, 2019
Tese de mestrado, Biologia Molecular e Genética, Universidade de Lisboa, Faculdade de Ciências, 2019Introduction: Due to the discrepancy in the number of X chromosomes between the sexes in many animal species, dosage compensation mechanisms have evolved ...
Gil, Cláudia Raquel Estopa
core   +4 more sources

LncRNA Xist通过调控SDF-1/CXCR4轴促进大鼠骨髓间充质干细胞增殖与迁移 [PDF]

Zhongshan Daxue xuebao. Yixue kexue ban, 2020
【目的】探讨lncRNA Xist在大鼠骨髓间充质干细胞（BMSC）增殖和迁移中的作用及其可能机制。【方法】取3周龄的雌性SD大鼠的股骨和胫骨，分离BMSC细胞，体外培养并鉴定。设计并筛选对lncRNA Xist沉默效率高的siRNA；利用Lipo2000分别将si-Xist和si-NC转染入实验组（si-Xist组）和对照组（si-NC组）BMSC中。CCK-8实验检测各组BMSC增殖能力。划痕及Transwell迁移实验检测各组BMSC横向和纵向迁移能力。qPCR验证lncRNA ...
段亚妮, 木拉提·阿比来列提, 朱雁秋, 唐镭蕾, 朱俊颖, 覃杰   +5 more
doaj   +1 more source

LncRNA-XIST Competitively Binds to MicroRNA-532-5p to Regulate PTEN Expression, Exacerbating Cerebral Ischemia-Reperfusion Injury. [PDF]

Adv Biol (Weinh)
Cerebral ischemia‐reperfusion injury (CIRI) is a severe neurological condition. LncRNA‐XIST is closely associated with CIRI; however, its underlying mechanism remains unclear.
Lu X, Chen L, Qian L, Zhang X, Wang Y, Yu B.   +5 more
europepmc   +2 more sources

Interfering lncRNA XIST inhibits the growth of salivary adenoid cystic carcinoma cells and improves cisplatin sensitivity by up-regulating miR-429 [PDF]

Xin yixue, 2022
ObjectiveTo investigate the regulatory effect and mechanism of lncRNA XIST on salivary adenoid cystic carcinoma （SACC） cell growth and cisplatin （DDP） chemosensitivity.
Zhang Xuan, Ma Licheng, Sun Longxiao, Zhang Lei
doaj   +1 more source

Diagnostic Value of lncRNA XIST in Saliva for Early Peri-Implantitis. [PDF]

Oral Health Prev Dent
To analyse the relative expression and diagnostic potential of lncRNA XIST (XIST) in peri-implantitis, and explore the related mechanism of XIST in peri-implantitis.XIST expression in saliva of patients with peri-implantitis was detected by qRT-PCR. The diagnostic significance of XIST in peri-implantitis was assessed by ROC curve.
Chai M, Zhang J, Meng Q, Liu A.
europepmc   +3 more sources