Results 141 to 150 of about 72,001 (287)
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Droplet, EarlyView.Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
Bayinqiaoge +2 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Drug Testing and Analysis, EarlyView.Concentration ranges, dose–concentration relationships, and metabolite‐to‐parent drug ratios of therapeutic opioids were evaluated in hair and skin swab samples of 150 pediatric patients. Skin‐derived matrices such as sweat or sebum were shown to contribute to analyte incorporation into hair in a systematic manner.
Max Polke +7 more
wiley +1 more source
Ethyl Glucuronide in Hair: A 10‐Year Overview
Drug Testing and Analysis, EarlyView.The present study builds on a unique collection of more than 68,000 hair EtG results collected in the Northen Italy between 2013 and 2022. We investigated trends in alcohol consumption in terms of age, gender, recidivism, applicants, sampling region, sampling length, across seasons, and the COVID‐19.
Sara Casati +8 more
wiley +1 more source
Neural Network‐Based Detection of Adulterants in Opioid Samples Using IR Absorption Spectroscopy
Drug Testing and Analysis, EarlyView.We construct a neural network for the classification of bromazolam and fluorofentanyl in illicit opioid samples. The model outperforms a random forest classifier and shows elevated performance for low concentration samples. ABSTRACT Community‐based drug checking services are challenged in their ability to reliably detect low concentration adulterants ...
Joshua Jai +4 more
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Quadruple hydrogen‐bonded high‐adhesion ionogels for gesture recognition and real‐time NH3 sensing. Ionogels have garnered significant attention in flexible sensing due to their outstanding mechanical properties, conductivity, and stability. However, establishing a robust and stable adhesive interface with various substrates remains a significant ...
Haohao Lin +7 more
wiley +1 more source
Machine Learning–Enhanced Fluorescence Cryptography with NADH‐Responsive Polymer Dots
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.This study presents a smart anticounterfeiting system using semiconducting polymer dots (Pdots) that exhibit tunable fluorescence responses to NADH. By integrating these dynamic optical signals with machine learning–based decoding, the work establishes a secure and intelligent encryption platform, showing a novel strategy that links chemical sensing ...
Zhengkun Zhan +7 more
wiley +1 more source
ELECTROPHORESIS, EarlyView.ABSTRACT This study describes the use of microchip micellar electrokinetic chromatography (MEKC) integrated with capacitively coupled contactless conductivity detection (C4D) for the determination of monoethylene glycol (MEG) in gas condensate samples.
Maurício M. L. Pereira +6 more
wiley +1 more source