Results 71 to 80 of about 72,001 (287)

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.

PLoS Genetics, 2009
The prevalence of obesity (body mass index (BMI) > or =30 kg/m(2)) is higher in African Americans than in European Americans, even after adjustment for socioeconomic factors, suggesting that genetic factors may explain some of the difference. To identify
Ching-Yu Cheng, W H Linda Kao, Nick Patterson, Arti Tandon, Christopher A Haiman, Tamara B Harris, Chao Xing, Esther M John, Christine B Ambrosone, Frederick L Brancati, Josef Coresh, Michael F Press, Rulan S Parekh, Michael J Klag, Lucy A Meoni, Wen-Chi Hsueh, Laura Fejerman, Ludmila Pawlikowska, Matthew L Freedman, Lina H Jandorf, Elisa V Bandera, Gregory L Ciupak, Michael A Nalls, Ermeg L Akylbekova, Eric S Orwoll, Tennille S Leak, Iva Miljkovic, Rongling Li, Giske Ursin, Leslie Bernstein, Kristin Ardlie, Herman A Taylor, Eric Boerwinckle, Joseph M Zmuda, Brian E Henderson, James G Wilson, David Reich   +36 more
doaj   +1 more source

Suspect screening of maternal serum to identify new environmental chemical biomonitoring targets using liquid chromatography-quadrupole time-of-flight mass spectrometry. [PDF]

, 2017
The use and advantages of high-resolution mass spectrometry (MS) as a discovery tool for environmental chemical monitoring has been demonstrated for environmental samples but not for biological samples.
Friesen, Matthew M, Gerona, Roy R, Lin, Thomas, Pan, Janet, Schwartz, Jackie M, Woodruff, Tracey J   +5 more
core   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Search for intracranial aneurysm susceptibility gene(s) using Finnish families

BMC Medical Genetics, 2002
Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured intracranial aneurysms (IA).
Ryynänen Markku, Hernesniemi Juha, Ronkainen Antti, Kuivaniemi Helena, Vongpunsawad Sompong, Olson Jane M, Kim Lee-Lian, Tromp Gerard   +7 more
doaj   +1 more source

Co-occurring risk factors for alcohol dependence and habitual smoking. [PDF]

, 2000
Smoking and alcohol dependence frequently occur together, and both behaviors are determined in part by genetic influences. The Collaborative Study on the Genetics of Alcoholism (COGA), which is investigating the genetic factors contributing to alcohol ...
Bierut, LJ, Hesselbrock, V, Reich, T, Schuckit, MA   +3 more
core  

Developmental dyslexia: Genetic dissection of a complex cognitive trait [PDF]

, 2002
Developmental dyslexia, a specific impairment of reading ability despite adequate intelligence and educational opportunity, is one of the most frequent childhood disorders.
DeFries, J., Fisher, S.
core   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

A genome-wide linkage scan identifies multiple quantitative trait loci for HDL-cholesterol levels in families with premature CAD and MI

Journal of Lipid Research, 2010
Plasma HDL cholesterol levels (HDL-C) are an independent predictor of coronary artery disease (CAD). We have completed a genome-wide linkage scan for HDL-C in a US cohort consisting of 388 multiplex families with premature CAD (GeneQuest).
Rong Yang, Lin Li, Sara Bretschger Seidelmann, Gong-Qing Shen, Sonia Sharma, Shaoqi Rao, Kalil G. Abdullah, Kenneth G. MacKinlay, Robert C. Elston, Qiuyun Chen, Eric J. Topol, Qing Kenneth Wang   +11 more
doaj   +1 more source

Microsatellite diversity analysis and QTL identification among progenies derived from aerobic × basmati rice (Oryza sativa) cross under direct-seeded conditions

The Indian Journal of Agricultural Sciences, 2020
The present investigation was designed to identify QTL associated with various traits under aerobic condition using F3 and F4 population derived from the cross MASARB25 (aerobic rice) and IB370 (basmati rice).
RAHUL KUMAR MEENA, KULDEEP KUMAR, NABIN BHUSAL, RAJINDER KUMAR JAIN, SUNITA JAIN   +4 more
doaj   +1 more source