Results 31 to 40 of about 12,197,984 (249)

Corrigendum: Usefulness and Potential Pitfalls of Long-Acting Growth Hormone Analogues [PDF]

Frontiers in Endocrinology, 2021
Kevin C. J. Yuen, Bradley S. Miller, Cesar L. Boguszewski, Andrew R. Hoffman   +3 more
doaj   +2 more sources

Corrigendum: Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation [PDF]

Frontiers in Endocrinology, 2023
Martin Bidlingmaier, Beverly M.K. Biller, David Clemmons, Jens Otto L. Jørgensen, Hiroshi Nishioka, Yutaka Takahashi, Yutaka Takahashi   +6 more
doaj   +2 more sources

A Cell-Based Strategy for Bioactivity Determination of Long-Acting Fc-Fusion Recombinant Human Growth Hormone

Molecules, 2019
The long-acting growth hormone (LAGH) is a promising alternative biopharmaceutical to treat growth hormone (GH) deficiency in children, and it was developed using a variety of technologies by several pharmaceutical companies. Most LAGH preparations, such
Wenrong Yao, Lei Yu, Wenhong Fan, Xinchang Shi, Lan Liu, Yonghong Li, Xi Qin, Chunming Rao, Junzhi Wang   +8 more
doaj   +2 more sources

Preclinical Investigations of a Novel PEGylated Long-Acting Human Growth Hormone

Drug Design, Development and Therapy
Jun Wang,1,2 He Wang,1,2 Rong Wang,1,2 Yu Zhuang,1,2 Chenyang Jiang,1,2 Baixue Zhao,1,2 Zhen Xu,1,2 Bruce Yong Ma1,2 1Zonhon Biopharma Institute, Inc., Changzhou, Jiangsu, People’s Republic of China; 2Jiangsu Engineering Research Center for Precision ...
Wang J, Wang H, Wang R, Zhuang Y, Jiang C, Zhao B, Xu Z, Ma BY   +7 more
doaj   +3 more sources

First Clinical Study on Long-Acting Growth Hormone Therapy in Children with Turner Sydrome. [PDF]

Horm Metab Res, 2022
Gao X, Chen J, Cao B, Dou X, Peng Y, Su C, Qin M, Wei L, Fan L, Zhang B, Gong C.   +10 more
europepmc   +2 more sources

Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency [PDF]

Annals of Pediatric Endocrinology & Metabolism
Long-acting growth hormones (LAGHs) represent a significant advancement in the treatment of pediatric GH deficiency, offering an alternative to daily recombinant human GH (rhGH) therapy.
Chiara Rodaro, Gianluca Tamaro, Elena Faleschini, Gianluca Tornese   +3 more
doaj   +4 more sources

Effects of different doses of long-acting growth hormone in treating children with growth hormone deficiency. [PDF]

World J Clin Cases, 2023
β cells are the main cells responsible for the hypoglycemic function of pancreatic islets, and the insulin secreted by these cells is the only hormone that lowers blood glucose levels in the human body. β cells are regulated by various factors, among which neurotransmitters make an important contribution.
Xia W, Wang T, Pan JY.
europepmc   +3 more sources

Long-Acting Growth Hormone [PDF]

Pediatric Drugs, 2013
Human growth hormone (GH) is a 22 kDa protein synthesized and secreted in the anterior pituitary gland. GH synthesis and release is induced by hypothalamic GHreleasing hormone (GHRH) and ghrelin and attenuated by somatostatin and negative feedback by insulin-like growth factor (IGF)-I [1].
Höybye, Charlotte, Christiansen, Jens Sandahl   +1 more
openaire   +3 more sources

Influence of long-acting growth hormone analogs on other hypothalamic-pituitary axes: a real-world study. [PDF]

J Endocrinol Invest
Introduction/purpose Long‑acting growth hormone (LAGH) formulations have emerged to address poor adherence to daily recombinant human growth hormone (rhGH), offering reduced injection frequency and comparable efficacy.
Rodari G, Profka E, Pedroli A, Citterio V, Collini V, Mazzi C, Mantovani G, Giavoli C.   +7 more
europepmc   +2 more sources

Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan

Drug Design, Development and Therapy
Bradley S Miller,1 Jo Blair,2 Reiko Horikawa,3 Agnès Linglart,4– 7 Kevin CJ Yuen8 1Division of Pediatric Endocrinology, University of Minnesota Medical School, MHealth Fairview Masonic Children’s Hospital, Minneapolis, MN, USA; 2Department of Paediatric ...
Miller BS, Blair J, Horikawa R, Linglart A, Yuen KC   +4 more
doaj   +1 more source