Results 21 to 30 of about 3,183,091 (359)

Pain-motor integration in the primary motor cortex in Parkinson's disease [PDF]

open access: yes, 2017
In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through ...
Berardelli, Alfredo   +9 more
core   +1 more source

Tonic and phasic nitric oxide signals in hippocampal long-term potentiation [PDF]

open access: yes, 2006
Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Garthwaite, J, Hopper, RA
core   +1 more source

Synaptic tagging and capture in the living rat [PDF]

open access: yes, 2012
In isolated hippocampal slices, decaying long-term potentiation can be stabilized and converted to late long-term potentiation lasting many hours, by prior or subsequent strong high-frequency tetanization of an independent input to a common population of
A Gasbarri   +57 more
core   +1 more source

Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons

open access: yesMolecular Brain, 2022
Cyclin-dependent kinase 5 (Cdk5) /p35 is involved in many developmental processes of the central nervous system. Cdk5/p35 is also implicated in synaptic plasticity, learning and memory.
Miyuki Takahashi   +9 more
doaj   +1 more source

Dependence receptor involvement in subtilisin-induced long-term depression and in long-term potentiation [PDF]

open access: yes, 2016
The serine protease subtilisin induces a form of long-term depression (LTD) which is accompanied by a reduced expression of the axo-dendritic guidance molecule Unco-ordinated-5C (Unc-5C).
Darlington, L. Gail   +2 more
core   +1 more source

State based model of long-term potentiation and synaptic tagging and capture [PDF]

open access: yes, 2009
Recent data indicate that plasticity protocols have not only synapse-specific but also more widespread effects. In particular, in synaptic tagging and capture (STC), tagged synapses can capture plasticity-related proteins, synthesized in response to ...
A Govindarajan   +50 more
core   +5 more sources

Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons

open access: yesFrontiers in Cellular Neuroscience, 2019
Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi   +9 more
doaj   +1 more source

Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation [PDF]

open access: yes, 2010
Weakly tetanized synapses in area CA1 of the hippocampus that ordinarily display long-term potentiation lasting ~3 h (called early-LTP) will maintain a longer-lasting change in efficacy (late-LTP) if the weak tetanization occurs shortly before or after ...
Bito, Haruhiko   +5 more
core   +2 more sources

Long-term potentiation and memory. [PDF]

open access: yesPhysiological Reviews, 2004
Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004; 10.1152/physrev.00014.2003.—One of the most significant challenges in neuroscience is to identify the cellular and molecular processes that underlie learning and memory formation. The past decade has seen remarkable progress in understanding changes that accompany certain forms
M. Lynch
semanticscholar   +3 more sources

Cardiac Arrest Induces Ischemic Long-Term Potentiation of Hippocampal CA1 Neurons That Occludes Physiological Long-Term Potentiation

open access: yesNeural Plasticity, 2018
Ischemic long-term potentiation (iLTP) is a form of synaptic plasticity that occurs in acute brain slices following oxygen-glucose deprivation. In vitro, iLTP can occlude physiological LTP (pLTP) through saturation of plasticity mechanisms.
James E. Orfila   +7 more
doaj   +1 more source

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