Results 231 to 240 of about 185,323 (261)

Long Non-Coding RNAs and Prostate Cancer

Journal of Nanoscience and Nanotechnology, 2013
A new class of transcripts, long non-coding RNAs (IncRNAs), has been recently found to be pervasively transcribed in the genome. These mRNA-like molecules, which lack significant protein-coding capacity, once thought to be a part of the dark matter, now have been implicated in a wide range of biological functions through diverse and as yet poorly ...
Dachuang, Liu, Bin, Xu, Shuqiu, Chen, Yu, Yang, Xiaowen, Zhang, Jin, Liu, Kai, Lu, Lei, Zhang, Chunhui, Liu, Yuming, Zhao, Hua, Jiang, Ning, Liu, Ming, Chen   +12 more
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Long Non-Coding RNAs

2011
Long non-coding RNAs (lncRNAs), tentatively defined as ncRNAs of more than two hundred nucleotides in length, are characterized by the complexity and diversity of their sequences and mechanisms of action. Based on genome-wide studies, more than 3, 300 of them exist, but to date only the limited number of functional lncRNAs have been identified and ...
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Long non-coding RNA PVT1 and cancer

Biochemical and Biophysical Research Communications, 2016
Genome-wide sequencing technologies have led to the identification of many non-coding RNAs and revealed an important role for these molecules in cancer. Although there have been many studies on the role of short non-coding RNAs in cancer, much work remains to characterize the functions of long non-coding RNAs. PVT1, a long non-coding RNA encoded by the
Ming, Cui, Lei, You, Xiaoxia, Ren, Wenjing, Zhao, Quan, Liao, Yupei, Zhao   +5 more
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Long non-coding RNAs in pancreatic cancer

Clinica Chimica Acta
This article reviews the recent advances in pathogenesis, diagnosis and treatment of pancreatic cancer, as well as the relationship between long non-coding RNA (lncRNA) in disease progression. Unfortunately, pancreatic cancer has no early symptoms and quickly invades surrounding tissue and organs, making it one of the deadliest.
Yuan, Chen, Xiaohua, Ye, Minli, Hu, Yibing, Hu, Jin, Ding   +4 more
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Getting the GIST of long non-coding RNA

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal malignancies of the digestive tract. About 85 % of them have gain-of-function mutations in KIT or PDGFRA, resulting in constitutive activation of these receptor tyrosine kinases, which are drivers of GIST development.
Giulia, Zerbo, Daniela, Gasparotto
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Long non-coding RNAs: definitions, functions, challenges and recommendations

Nature Reviews Molecular Cell Biology, 2023
Chandrasekhar Kanduri, Jeanne Lawrence, Jeremy Wilusz   +2 more
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Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery

Nature Reviews Molecular Cell Biology, 2020
Uttiya Basu, Hachung Chung
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Non-coding RNAs in disease: from mechanisms to therapeutics

Nature Reviews Genetics, 2023
Manuela Ferracin, Kinga Nemeth, George A Calin   +2 more
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Gene regulation by long non-coding RNAs and its biological functions

Nature Reviews Molecular Cell Biology, 2020
Luisa Statello, Ling-Ling Chen, Maite Huarte   +2 more
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The functions and unique features of long intergenic non-coding RNA

Nature Reviews Molecular Cell Biology, 2017
Paul Khavari, Yuning Wei
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