Results 21 to 30 of about 173,449 (258)
PVT1: a rising star among oncogenic long non-coding RNAs [PDF]
, 2015 It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and (mis)function.
Colombo, Teresa +3 more
core +4 more sources
Role of Related Regulatory Long Noncoding RNAs on Mammalian Spermatogenesis
Reproductive and Developmental Medicine, 2017 Long noncoding RNAs (lncRNAs) are transcribed by RNA molecules, which are longer than 200 nucleotides that lack an open reading frame of significant length and possess no obvious protein-coding capacity.
Kang-Sheng Liu +4 more
doaj +1 more source
Noncoding RNAs and gene silencing [PDF]
, 2007 Noncoding RNA has long been proposed to control gene expression via sequence-specific interactions with regulatory regions. Here, we review the role of noncoding RNA in heterochromatic silencing and in the silencing of transposable elements (TEs ...
Irvine, D. V. +2 more
core +1 more source
Technology in Cancer Research & Treatment, 2020 Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient ...
Ke-kang Sun MD +4 more
doaj +1 more source
The Regulatory Activity of Noncoding RNAs in ILCs
Cells, 2021 Innate lymphoid cells (ILCs) are innate lymphocytes playing essential functions in protection against microbial infections and participate in both homeostatic and pathological contexts, including tissue remodeling, cancer, and inflammatory disorders.
Alessio Grimaldi +8 more
doaj +1 more source
Human cancer long non-coding RNA transcriptomes. [PDF]
PLoS ONE, 2011 Once thought to be a part of the 'dark matter' of the genome, long non-coding RNAs (lncRNAs) are emerging as an integral functional component of the mammalian transcriptome.
Ewan A Gibb +10 more
doaj +1 more source
Role of noncoding RNA in vascular remodelling [PDF]
, 2016 Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H. +2 more
core +1 more source
Cytokines and Long Noncoding RNAs [PDF]
Cold Spring Harbor Perspectives in Biology, 2017 Cytokines and long noncoding RNAs (lncRNAs) are intertwined in the regulatory circuit controlling immunity. lncRNA expression levels are altered following cytokine stimulation in a cell-type-specific fashion. lncRNAs, in turn, regulate the inducible expression of cytokines following immune activation.
Susan, Carpenter +1 more
openaire +2 more sources
EBioMedicine, 2021 Background: Transcriptional regulators are seminal players in the onset and progression of prostate cancer. However, clarification of their underlying regulatory circuits and mechanisms demands considerable effort.
Mei Jiang +7 more
doaj +1 more source
Long non-coding RNA SOX2OT: Expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis [PDF]
, 2015 SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA which harbors one of the major regulators of pluripotency, SOX2 gene, in its intronic region.
Jazi, M.S. +3 more
core +1 more source