Results 71 to 80 of about 46,383 (210)
The Journal of Clinical Pharmacology, Volume 66, Issue 2, February 2026.Abstract Cytochrome P450 3A4 (CYP3A4) is an important drug‐metabolizing enzyme, whose function is impacted by age, sex, body weight, pregnancy, and disease. It is also the site of major drug interactions involving inhibition and induction. Because CYP3A4 is expressed in the intestine and liver, investigators have sought to study its function in both ...
David Rodrigues
wiley +1 more source
Characteristics, Immunological Response & Treatment Outcomes of HIV-2 Compared with HIV-1 & Dual Infections (HIV 1/2) in Mumbai [PDF]
, 2010 Information available on HIV-2 and dual infection (HIV-1/2) is limited. This study was carried out among HIV positive individuals in an urban referral clinic in Khar, Mumbai, India, to report on relative proportions of HIV-1, HIV-2 and HIV-1/2 and ...
Alaka, Deshpande +8 more
core +1 more source
Solid Dispersions as a Tool for Innovation in the Food Industry: A Path From Pharma to Food
Journal of Food Science, Volume 91, Issue 2, February 2026.ABSTRACT Solid dispersion (SD) is a technique used to improve the solubility of poorly water‐soluble compounds by dispersing them in a solid water‐friendly carrier. Current trends indicate that natural‐based alternatives are increasingly replacing synthetic carriers, benefiting the pharmaceutical industry, where they were first adopted, and paving the ...
Stephany C. de Rezende +3 more
wiley +1 more source
Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study. [PDF]
, 2015 Increased levels of markers of systemic inflammation have been associated with serious non-AIDS events even in patients on fully suppressive antiretroviral therapy.
Arenas-Pinto, A +5 more
core +1 more source
Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic
Microbial Biotechnology, Volume 19, Issue 2, February 2026.Replication cycle of HIV‐1. The scheme provides an overview from virus entry over reverse transcription of viral RNA into viral DNA, provirus DNA integration into the host genome, genome expression by transcription and translation, proteolytic processing of the viral polyproteins, viral maturation to viral release from the cell. The various targets for
Harald Brüssow
wiley +1 more source
Immunovirological outcomes and resistance patterns at 4 years of antiretroviral therapy use in HIV-infected patients in Cambodia [PDF]
, 2011 Objectives To report immunovirological outcomes and resistance patterns in adults treated with triple combination antiretroviral therapy (cART) for 4 years in an HIV programme of Phnom Penh, Cambodia.
Balkan, Suna +7 more
core +2 more sources
Associations of SLCO1B1 polymorphism with virological efficacy in children with HIV infection
Сибирский научный медицинский журналThe aim of the study was to identify the association between polymorphism of the SLCO1B1 gene and virological efficacy in children receiving lopinavir as part of their antiretroviral therapy.Material and methods.
A. Yu. Sambyalova +9 more
doaj +1 more source
Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]
, 2015 Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu +3 more
core +1 more source
Oral Melatonin in Critically Ill Patients With COVID‐19: A Quasi‐Experimental Pragmatic Trial
Journal of Medical Virology, Volume 98, Issue 1, January 2026.ABSTRACT Melatonin has demonstrated antioxidant, anti‐inflammatory, and potential antiviral properties. Its therapeutic role in critically ill COVID‐19 patients admitted to intensive care was underexplored at the start of the pandemic. We conducted a quasi‐experimental, pragmatic study over 4 consecutive uninterrupted time periods alternating control ...
Miguel Sánchez‐García +22 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesThis study evaluates clinical, virological and immunological responses to antiretroviral (ARV) therapy based on Lopinavir/ritonovir (LPV/r) in previously protease -inhibitor-experienced children.
Daisy Maria Machado +9 more
doaj +1 more source