Results 61 to 70 of about 97,118 (179)

Ductaler Abgang der LPA – erfolgreiche Rekrutierung der LPA durch 2-Stufenkonzept

, 2015
Der ductale Abgang einer Pulmonalarterie führt nach neonatalem Verschluss des Ductus zu einer fehlenden Perfusion der betreffenden Pulmonalarterie. Bei Kindern ohne zusätzliche kardiovaskuläre Fehlbildungen (z.B. Fallout Tetralogie, VSD) bleibt dies klinisch meist unbemerkt, die Patienten[for full text, please go to the a.m. URL]
Wiegand, G, Sieverding, L, Froese, G, Schlensak, C, Hofbeck, M   +4 more
openaire   +1 more source

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA‐binding proteins in activation of LPA receptors [PDF]

FEBS Letters, 2002
Lysophosphatidic acid (LPA) exerts multiple biological functions through G protein‐coupled receptors (EDG2/LPA1, EDG4/LPA2, and EDG7/LPA3) and is present in serum where it is associated with albumin. In this study we examined LPA activity in various biological fluids by measuring the LPA‐induced increase in the intracellular concentration of calcium ...
Hama, Kotaro, Bandoh, Koji, Kakehi, Yoshiyuki, Aoki, Junken, Arai, Hiroyuki   +4 more
openaire   +2 more sources

Structural and functional differences of subspecies of apoA-I-containing lipoprotein in patients with plasma cholesteryl ester transfer protein deficiency.

Journal of Lipid Research, 1995
ApoA-I-containing lipoproteins exist in plasma in two main forms: one contains only apoA-I (LpA-I) while the other contains both apoA-I and apoA-II (LpA-I/A-II).
T Ohta, R Nakamura, K Takata, Y Saito, S Yamashita, S Horiuchi, I Matsuda   +6 more
doaj   +1 more source

Fluid Communities: A Competitive, Scalable and Diverse Community Detection Algorithm

, 2017
We introduce a community detection algorithm (Fluid Communities) based on the idea of fluids interacting in an environment, expanding and contracting as a result of that interaction.
Ayguadé, Eduard, Cortés, Ulises, Garcia-Gasulla, Dario, Labarta, Jesús, Moreno, Jonatan, Parés, Ferran, Suzumura, Toyotaro, Vilalta, Armand   +7 more
core   +1 more source

Lysophosphatidic acid (LPA) and angiogenesis [PDF]

Angiogenesis, 2008
Lysophosphatidic acid (LPA) is a simple lipid with many important biological functions such as the regulation of cellular proliferation, cellular migration, differentiation, and suppression of apoptosis. Although a direct angiogenic effect of LPA has not been reported to date, there are indications that LPA promotes angiogenesis.
Carol M, Rivera-Lopez, Amy L, Tucker, Kevin R, Lynch   +2 more
openaire   +2 more sources

A retrospective record-based study to evaluate the profile of TB patients diagnosed and registered at DOTS center at the tertiary care center and to study the gaps in the implementation of the latest guidelines toward TB elimination

The Journal of Association of Chest Physicians
Context: Tuberculosis (TB) has infected mankind since time immemorial. India has been a breeding ground for this disease due to high population density and lack of awareness and education in the population.
Ruchi Arora Sachdeva, Sahil Singh, MK Sen   +2 more
doaj   +1 more source

Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway

Frontiers in Physiology, 2018
Background: Lysophosphatidic acid (LPA), as a phospholipid signal molecule, participates in the regulation of various biological functions. Our previous study demonstrated that LPA induces cardiomyocyte hypertrophy in vitro; however, the functional role ...
Jinjing Yang, Jinjing Yang, Jinjing Yang, Jiyao Xu, Jiyao Xu, Xuebin Han, Xuebin Han, Hao Wang, Yuean Zhang, Yuean Zhang, Jin Dong, Jin Dong, Yongzhi Deng, Yongzhi Deng, Jingping Wang, Jingping Wang   +15 more
doaj   +1 more source

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species [PDF]

FEBS Letters, 2000
We examined the structure–activity relationship of cloned lysophosphatidic acid (LPA) receptors (endothelial cell differentiation gene (EDG) 2, EDG4, and EDG7) by measuring [Ca2+]i in Sf9 insect cells expressing each receptor using LPA with various acyl chains bound at either the sn‐1 or the sn‐2 position of the glycerol backbone.
Bandoh, Koji, Aoki, Junken, Taira, Akitsu, Tsujimoto, Masafumi, Arai, Hiroyuki, Inoue, Keizo   +5 more
openaire   +2 more sources

Lipoprotein(a) accelerated the progression of atherosclerosis in patients with end-stage renal disease

BMC Nephrology, 2018
Background Increased plasma level of lipoprotein(a) (Lpa) is a risk factor of cardiovascular diseases. This study aimed to explore the role of Lpa in the progression of atherosclerosis in patients with end-stage renal disease (ESRD) and to investigate ...
Kun Ling Ma, Tie Kai Gong, Ze Bo Hu, Yang Zhang, Gui Hua Wang, Liang Liu, Pei Pei Chen, Jian Lu, Chen Chen Lu, Bi Cheng Liu   +9 more
doaj   +1 more source

How memory generates heterogeneous dynamics in temporal networks

, 2014
Empirical temporal networks display strong heterogeneities in their dynamics, which profoundly affect processes taking place on these networks, such as rumor and epidemic spreading.
Barrat, Alain, Génois, Mathieu, Vestergaard, Christian L.   +2 more
core   +3 more sources