Results 61 to 70 of about 113,253 (324)

Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain

Molecular Pain, 2009
Background We previously reported that intrathecal injection of lysophosphatidylcholine (LPC) induced neuropathic pain through activation of the lysophosphatidic acid (LPA)-1 receptor, possibly via conversion to LPA by autotaxin (ATX).
Aoki Junken, Chun Jerold, Inoue Makoto, Nagai Jun, Uchida Hitoshi, Ma Lin, Ueda Hiroshi   +6 more
doaj   +1 more source

Plasma concentrations of lysophosphatidic acid and the expression of its receptors in peripheral blood mononuclear cells are altered in patients with cocaine use disorders

Translational Psychiatry, 2023
We have recently reported alterations in the plasma concentrations of lysophosphatidic acid (LPA) in patients with substance use disorders. In order to further explore the potential role of the LPA signaling system as biomarker in cocaine use disorders ...
María Flores-López, Nuria García-Marchena, Francisco J. Pavón-Morón, Nerea Requena-Ocaña, Laura Sánchez-Marín, Laura Martín-Chaves, Mónica García-Medina, Carmen Pedraza, Estela Castilla-Ortega, Juan J. Ruiz, Fernando Rodríguez de Fonseca, Pedro Araos, Antonia Serrano   +12 more
doaj   +1 more source

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source

Role of lysophosphatidic acid receptor LPA₂ in the development of allergic airway inflammation in a murine model of asthma

Respiratory Research, 2009
Background Lysophosphatidic acid (LPA) plays a critical role in airway inflammation through G protein-coupled LPA receptors (LPA1-3). We have demonstrated that LPA induced cytokine and lipid mediator release in human bronchial epithelial cells.
Chun Jerold, Evgeny Berdyshev, Pendyala Srikanth, He Donghong, Tong Jiankun, Zhao Yutong, Sperling Anne I, Natarajan Viswanathan   +7 more
doaj   +1 more source

Optimization of the derivative expansion in the nonperturbative renormalization group [PDF]

, 2002
We study the optimization of nonperturbative renormalization group equations truncated both in fields and derivatives. On the example of the Ising model in three dimensions, we show that the Principle of Minimal Sensitivity can be unambiguously ...
A. Haupt, A. Pelissetto, B. Bergerhoff, Bertrand Delamotte, C. Bagnuls, C. Wetterich, C. Wetterich, C. Wetterich, C. Wetterich, C. Wetterich, C. Wetterich, D. Litim, D. Litim, D. Litim, D. Litim, D. Litim, Dominique Mouhanna, F. Höfling, G. von Gersdorff, G. Zumbach, J. Berges, J. Comellas, J. Polchinski, Julien Vidal, K. G. Wilson, K. I. Aoki, L. P. Kadanoff, L. Rosa, Léonie Canet, M. Grater, M. Hasenbusch, M. Kindermann, M. Tissier, M. Tissier, M. Tissier, N. Tetradis, O. Müller, P. Stevenson, R. D. Ball, R. Guida, S. Liao, S. Seide, T. R. Morris, T. R. Morris, T. R. Morris, T. R. Morris, T. R. Morris, T. R. Morris, T. R. Morris, T. R. Morris, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger, U. Ellwanger   +54 more
core   +3 more sources

ATX-LPA axis facilitates estrogen-induced endometrial cancer cell proliferation via MAPK/ERK signaling pathway

Molecular Medicine Reports, 2018
Autotaxin (ATX) is a key enzyme that converts lysophosphatidylcholine to lysophosphatidic acid (LPA). ATX is a crucial factor that facilitates cancer progression; however, the effect of ATX on endometrial cancer has not been explored.
G. Zhang, Yuan Cheng, Qi Zhang, Xiaoping Li, Jing-Yi Zhou, Jianliu Wang, Lihui Wei   +6 more
semanticscholar   +1 more source

Recyclable and Binder‐Free EGaIn–Carbon Liquid Metal Composite: A Sustainable Approach for High‐Performance Stretchable Electronics, Thermal‐Interfacing and EMI‐Shielding

Advanced Materials Technologies, EarlyView.
Binder‐free EGaIn–CB composite deliver printable, recyclable liquid‐metal conductors without sintering or polymer binders. Only 1.5 wt% CB yields shear‐thinning, high‐viscosity rheology, ∼60% bulk EGaIn conductivity, robust stretchability, high thermal conductivity, and strong EMI shielding (35 → 70 dB at 100% strain).
Elahe Parvini, Abdollah Hajalilou, Pedro A. Lopes, Tiago A. Morgado, Mahmoud Tavakoli   +4 more
wiley   +1 more source

High density lipoproteins with differing apolipoproteins: relationships to postprandial lipemia, cholesteryl ester transfer protein, and activities of lipoprotein lipase, hepatic lipase, and lecithin: cholesterol acyltransferase.

Journal of Lipid Research, 1994
To gain insight into metabolic determinants of high density lipoproteins (HDL) containing apolipoproteins A-I and A-II (LpA-I/A-II) and those containing A-I, but devoid of A-II (LpA-I), the plasma concentration of LpA-I and LpA-I/A-II within the HDL2 and
H O Mowri, J R Patsch, A Ritsch, B Föger, S Brown, W Patsch   +5 more
doaj   +1 more source

High Expression of Lysophosphatidic Acid Induces Nerve Injury in LSS Patients via AKT Mediated NF-κB p65 Pathway

Frontiers in Pharmacology, 2021
Lumbar spinal stenosis (LSS) is a spinal degenerative disease, complicated with nerve injury. Lysophosphatidic acid (LPA), a kind of glycerophospholipid molecule is elevated in the initial stages of neural injury.
Guiliang Zhai, Wenfei Liang, Yongjun Xu
doaj   +1 more source

Beam Scraping in the SPS for LHC Injection: Efficiency and Robustness Studies [PDF]

, 2008
The Large Hadron Collider (LHC) at CERN will be the world's most powerful accelerator when it is commissioned in fall 2008. Operation of the LHC will require injection of very high intensity beams. Fast transverse beam scrapers have been installed in the
Letnes, Paul/LPA
core