Results 71 to 80 of about 97,118 (179)

Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis

Journal of Lipid Research, 2002
The aim of the present work was to depict the metabolic pathways involved in extracellular production of lysophosphatidic acid (LPA) by adipocytes. LPA was followed by quantifying the accumulation of LPA in the incubation medium (conditioned medium, CM ...
Stéphane Gesta, Marie-Françoise Simon, Astrid Rey, David Sibrac, Alexia Girard, Max Lafontan, Philippe Valet, Jean Sébastien Saulnier-Blache   +7 more
doaj   +1 more source

Transport studies of LPA electron beam towards the FEL amplification at COXINEL

, 2016
Laser Plasma Acceleration (LPA) [1] is an emerging concept enabling to generate electron beams with high energy, high peak current and small transverse emittance within a very short distance. The use of LPA can be applied to the Free Electron Laser (FEL)
Briquez, F., Couprie, M. E., Khojoyan, M, Labat, M., Loulergue, A., Marcouillé, O., Marteau, F., Sharma, G.   +7 more
core   +1 more source

Strong-coupling phases of the anisotropic Kardar-Parisi-Zhang equation

, 2014
We study the anisotropic Kardar-Parisi-Zhang equation using nonperturbative renormalization group methods. In contrast to a previous analysis in the weak-coupling regime we find the strong coupling fixed point corresponding to the isotropic rough phase ...
Canet, Léonie, Kloss, Thomas, Wschebor, Nicolás   +2 more
core   +2 more sources

Convergent Regulation of Neuronal Differentiation and Erk and Akt Kinases in Human Neural Progenitor Cells by Lysophosphatidic Acid, Sphingosine 1-Phosphate, and LIF: Specific Roles for the LPA1 Receptor

ASN Neuro, 2014
The bioactive lysophospholipids lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have diverse effects on the developing nervous system and neural progenitors, but the molecular basis for their pleiotropic effects is poorly understood.
Phillip Callihan, Mourad W. Ali, Hector Salazar, Nhat Quach, Xian Wu, Steven L. Stice, Shelley B. Hooks   +6 more
doaj   +1 more source

Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice

Journal of Lipid Research, 2013
Lysophosphatidic acid (LPA) is a bioactive lipid mediator. Concentrations of the major LPA species in mouse plasma decreased uniformly following administration of a potent selective inhibitor of the LPA-generating lysophospholipase D autotaxin ...
Abdel K. Salous, Manikandan Panchatcharam, Manjula Sunkara, Paul Mueller, Anping Dong, Yuhuan Wang, Gregory A. Graf, Susan S. Smyth, Andrew J. Morris   +8 more
doaj   +1 more source

Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines

Journal of Lipid Research, 2005
It is generally thought that the large heterogeneity of human HDL confers antiatherogenic properties; however, the mechanisms governing HDL biogenesis and speciation are complex and poorly understood.
Larbi Krimbou, Houssein Hajj Hassan, Sacha Blain, Shirya Rashid, Maxime Denis, Michel Marcil, Jacques Genest   +6 more
doaj   +1 more source

LPA₃: Pharmacodynamic Differences Between Lysophosphatidic Acid and Oleoyl-Methoxy Glycerophosphothionate: Biased Agonism, Two Sites

Receptors
Background: Lysophosphatidic acid (LPA) receptor 3 (LPA3) is involved in many physiological and pathophysiological actions of this bioactive lipid, particularly in cancer.
K. Helivier Solís, M. Teresa Romero-Ávila, Ruth Rincón-Heredia, Juan Carlos Martínez-Morales, J. Adolfo García-Sáinz   +4 more
doaj   +1 more source

Unfolding communities in large complex networks: Combining defensive and offensive label propagation for core extraction

, 2011
Label propagation has proven to be a fast method for detecting communities in large complex networks. Recent developments have also improved the accuracy of the approach, however, a general algorithm is still an open issue.
Bajec, Marko, Šubelj, Lovro
core   +1 more source

Involvement of LPA Receptor 3 in LPA-induced BGC-803 Cell Migration

Mongolian Journal of Biological Sciences, 2013
Lysophosphatidic acid ˄ LPA ˅ is a bioactive phospholipid mediator, which elicits a variety of biological functions mainly through G-protein coupled receptors. Although LPA is shown to stimulate proliferation and motility via LPA receptors, LPAR1 and LPAR3 in several cancer cell lines, but the role of LPA receptors in gastric cancer cells is still ...
Erdene Oyungerel, Tserennadmid Tseveensuren, Oyun Gansukh, Li Rui Juan, Alatangaole Damirin   +4 more
openaire   +2 more sources

Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells

Journal of Lipid Research, 2003
Lysophosphatidic acid (LPA) is a receptor-active lipid mediator with a broad range of biological effects. Ovarian cancer cells synthesize LPA, which promotes their motility, growth, and survival.
Céline Luquain, Anurag Singh, Lixin Wang, Vishwanathan Natarajan, Andrew J. Morris   +4 more
doaj   +1 more source