Identification of LRP1B‐interacting proteins and inhibition of protein kinase Cα‐phosphorylation of LRP1B by association with PICK1 [PDF]
FEBS Letters, 2008 MINT‐6801173: Jip‐1b (uniprotkb:Q9WVI9‐1) physically interacts (MI:0218) with mLRP4 (uniprotkb:Q8VI56) by anti tag coimmunoprecipitation (MI:0007)
Shiroshima, Tomoko +2 more
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Cancer Medicine, 2021 Background Despite recent improvements in treatment technologies, such as surgical resection and chemoradiotherapy, the prognosis of patients with esophagogastric junction adenocarcinoma (EJA) remains poor due to early lymph node metastasis.
Rui Han +4 more
doaj +1 more source
Prognostic biomarkers correlated with immune infiltration in non‐small cell lung cancer
FEBS Open Bio, 2023 Lung cancer is the leading cause of cancer‐related mortality in men and women globally. Non‐small cell lung cancer (NSCLC) is the most prevalent subtype, accounting for 85–90% of all cancers.
Fei Xu +6 more
doaj +1 more source
Frontiers in Nutrition, 2022 High-throughput next-generation sequencing (NGS) provides insights into genome-wide mutations and can be used to identify biomarkers for the prediction of immune and targeted responses.
Cun Liu +12 more
doaj +1 more source
Association between the LRP1B and APOE loci and the development of Parkinson’s disease dementia
Brain, 2022 Abstract Parkinson’s disease (PD) is one of the most common age-related neurodegenerative disorders. Although predominantly a motor disorder, cognitive impairment and dementia are important features of PD, particularly in the later stages of the disease.
Raquel Real +20 more
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Alteration of the LRP1B Gene Region Is Associated with High Grade of Urothelial Cancer [PDF]
Laboratory Investigation, 2002 We have delineated regions of interest at chromosome 2q21.2, 2q36.3, and 2q37.1 by deletion mapping of 114 urothelial cancers (UC). Altogether, 17%, 18%, and 63% of the G1, G2, and G3 tumors displayed loss of heterozygosity at chromosome 2q, respectively, The region at 2q21.2 was narrowed down to the LRP1B gene (NT_005129.6).
Sigrun, Langbein +9 more
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BMC Cancer, 2021 Background PIK3CA is the second most frequently mutated gene in cancers and is extensively studied for its role in promoting cancer cell resistance to chemotherapy or targeted therapy.
Yu Yu +3 more
doaj +1 more source
LRP1B Polymorphisms Are Associated with Multiple Myeloma Risk in a Chinese Han Population [PDF]
Journal of Cancer, 2019 Multiple myeloma (MM) is an extremely complex plasma cell malignancy that is genetically heterogeneous. A recent Genome-wide association study (GWAS) indicated that variation at 2q22 (rs61070260) influences MM risk. This association has not been validated to date in a Chinese Han population.
Li, Bingjie +7 more
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Supplementary Table 2 - LRP1B as a potential gastric cancer biomarker
, 2023 Background: The aim of this study was to discover unique membrane proteins associated with gastric cancer (GC) in proteomics analysis. Methods: Using a data-independent acquisition strategy, we compared the relative expression levels of membrane proteins
Ji Miao (739159) +6 more
core +1 more source
Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients
Frontiers in Oncology, 2021 Small cell lung cancer (SCLC) is one of the severe malignancies with high mortality. Surgically resected tumor tissues from 50 Chinese SCLC patients were collected for next-generation sequencing to detect 520 cancer‐related genes.
Ting Yuan +6 more
doaj +1 more source