Red-Shifted Firefly Luciferase Optimized for Candida albicans In vivo Bioluminescence Imaging. [PDF]
, 2017 Candida albicans is a major fungal pathogen causing life-threatening diseases in immuno-compromised patients. The efficacy of current drugs to combat C. albicans infections is limited, as these infections have a 40-60% mortality rate.
Coste, A.T., Dorsaz, S., Sanglard, D.
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Sensitive dual color in vivo bioluminescence imaging using a new red codon optimized firefly luciferase and a green click beetle luciferase. [PDF]
PLoS ONE, 2011 BACKGROUND: Despite a plethora of bioluminescent reporter genes being cloned and used for cell assays and molecular imaging purposes, the simultaneous monitoring of multiple events in small animals is still challenging. This is partly attributable to the
Laura Mezzanotte +5 more
doaj +1 more source
A higher spectral range of beetle bioluminescence with infraluciferin
Frontiers in Bioengineering and Biotechnology, 2022 Coleopteran bioluminescence is unique in that beetle luciferases emit colors ranging between green (ca.550 nm) and red (ca.600 nm), including intermediate colors such as yellow and orange, allowing up to 3 simultaneous parameters to be resolved in vitro ...
Amit P. Jathoul +4 more
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Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin [PDF]
, 2006 Epithelial tight junctions participate in the regulation of gene expression by controlling the activity of transcription factors that can interact with junctional components.
Balda, MS +6 more
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A panel of Trypanosoma brucei strains tagged with blue and red-shifted luciferases for bioluminescent imaging in murine infection models. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND:Genetic engineering with luciferase reporter genes allows monitoring Trypanosoma brucei (T.b.) infections in mice by in vivo bioluminescence imaging (BLI). Until recently, luminescent T.b.
Nick Van Reet +4 more
doaj +1 more source
Translation initiation factor eIF3 promotes programmed stop codon readthrough. [PDF]
, 2015 Programmed stop codon readthrough is a post-transcription regulatory mechanism specifically increasing proteome diversity by creating a pool of C-terminally extended proteins.
Beznoskova, Petra +4 more
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Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays [PDF]
, 2018 The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an estimated 1 million new cases each year. Current treatments are toxic, expensive, difficult to administer, and resistance to them is emerging.
Berry, SL +6 more
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Luciferase‐Induced Photouncaging: Bioluminolysis
Angewandte Chemie International Edition, 2019 Abstract Bioluminescence resonance energy transfer (BRET) has been widely used for studying dynamic processes in biological systems such as protein–protein interactions and other signaling events. Aside from acting as a reporter, BRET can also turn on functions in living systems.
Dalu Chang +5 more
openaire +3 more sources
Chemical communication between synthetic and natural cells: a possible experimental design [PDF]
, 2013 The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca +5 more
core +3 more sources
Multiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies [PDF]
, 2014 The increased number of outbreaks of H5 and H7 LPAI and HPAI viruses in poultry has major public and animal health implications. The continuous rapid evolution of these subtypes and the emergence of new variants influence the ability to undertake ...
Cattoli, G. +11 more
core +12 more sources