Results 71 to 80 of about 3,794 (236)
Evaluation on the inclusion behavior of β-cyclodextrins with lycorine and its hydrochloride [PDF]
Xinyue Sun +7 more
openalex +1 more source
Production and antioxidant capacity of tissue cultures from four Amaryllidaceae species [PDF]
The aim of this study was (i) to produce tissue cultures capable of efficient plant regeneration from European naturally occurring protected and/or pharmacologically important Amaryllidaceae species and (ii) to test them for antioxidant activities in ...
Ajtay, Kitti +7 more
core +3 more sources
Purification of the Alkaloid Lycorine and Simultaneous Analysis of Ascorbic Acid and Lycorine by Micellar Electrokinetic Capillary Chromatography [PDF]
The pyrrolophenanthridine alkaloid lycorine has frequently been used as a specific inhibitor to help elucidate the function of ascorbic acid (vitamin C) in a wide range of biological processes. It was recently reported that this function can be exercised by inhibiting the activity of L-galactono-1,4-lactone dehydrogenase, the terminal enzyme of ...
M W, Davey +5 more
openaire +2 more sources
Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su +5 more
wiley +1 more source
Cytotoxic Activity And Mechanisms Of Action Of Crinum Asiaticum Extracts On Various Cancer Cell Lines [PDF]
Crinum asiaticum yang dikenali oleh penduduk tempatan sebagai tembaga suasa, digunakan dalam perubatan tradisional, untuk merawat inflamasi/bengkak dan tumor Crinum asiaticum, locally known as ‘tembaga suasa’, is used traditionally to treat ...
Mohd Yusoff, Sa'adiah
core
ABSTRACT Background Natural alkaloids are a structurally diverse class of bioactive compounds with significant therapeutic potential. This study aimed to evaluate the in vitro antiviral activity of various natural alkaloids against coronaviruses, clarify molecular effects via bioassays and docking, and explore structure–activity relationships.
Marcela Safratova +11 more
wiley +1 more source
Cytotoxicity Studies of Lycorine Alkaloids of the Amaryllidaceae [PDF]
The plant family Amaryllidaceae is renowned for its unique alkaloid constituents which possess a significant array of structural diversity. Several of these alkaloids are known for their interesting biological properties, of which galanthamine and pancratistatin have acquired a privileged status due to their relevance in the pharmaceutical arena.
Jerald J, Nair, Johannes, van Staden
openaire +2 more sources
Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali +7 more
wiley +1 more source
Objective: To investigate the differential of protein expression in CCl4 induced mice treated with lycorine. Methods: The present study was carried out to identify the differentially expressed protein in carbon tetrachloride (CCl4) induced oxidative ...
Soundarrajan Ilavenil +7 more
doaj +1 more source
Alkaloids isolated from members of the Amaryllidaceae plant family are promising anticancer agents. The purpose of the current study was to determine if the isocarbostyrils narciclasine, pancratistatin, lycorane, lycorine, crinane, and haemanthamine ...
Veronique Mathieu +10 more
doaj +1 more source

