PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor
Cell Death and Disease, 2021 Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment failure.
Chuanghua Luo +13 more
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Promoting inflammatory lymphangiogenesis by vascular endothelial growth factor-C (VEGF-C) aggravated intestinal inflammation in mice with experimental acute colitis [PDF]
Brazilian Journal of Medical and Biological Research, 2016 Angiogenesis and lymphangiogenesis are thought to play a role in the pathogenesis of inflammatory bowel diseases (IBD). However, it is not understood if inflammatory lymphangiogenesis is a pathological consequence or a productive attempt to resolve the ...
X.L. Wang, J. Zhao, L. Qin, M. Qiao
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Role of Extracellular Vesicles on Cancer Lymphangiogenesis and Lymph Node Metastasis
Frontiers in Oncology, 2021 Lymph node metastasis (LNM) of tumors is an established indicator of poor prognosis in patients. Tumor-associated lymphangiogenesis is a key step in LNM and has gained much attention. However, currently, there is no anti-tumor lymphangiogenesis drug used
Linlin Wang, Ling Li, Guiquan Zhu
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Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. [PDF]
PLoS ONE, 2011 Lymphangiogenesis is a common phenomenon observed during inflammation and engraftment of transplants, but its precise role in the immune response and underlying mechanisms of regulation remain poorly defined. Here we showed that in response to injury and
Na Yin +6 more
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Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]
, 2018 Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li +9 more
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Myeloid Cells and Lymphangiogenesis [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 The lymphatic vascular system and the hematopoietic system are intimately connected in ontogeny and in physiology. During embryonic development, mammalian species derive a first lymphatic vascular plexus from the previously formed anterior cardinal vein, whereas birds and amphibians have a lymphatic vascular system of dual origin, composed of lymphatic
Zumsteg, Adrian, Christofori, Gerhard
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The intestinal lymphatic system: Functions and metabolic implications [PDF]
, 2019 The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Cifarelli, Vincenza, Eichmann, Anne
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Cell Reports, 2019 Summary: Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels display organotypic function and develop in an organ-specific manner. In all settings,
Adam J. Vogrin +9 more
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Cellular & Molecular Biology Letters, 2023 Background Esophageal squamous carcinoma (ESCC) is a common malignancy that originates in the digestive tract. Lymph node metastasis (LNM) is a complicated process, and tumor lymphangiogenesis has been reported to be associated with the spread of tumor ...
Wenjian Yao +6 more
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Kuoxin Decoction promotes lymphangiogenesis in zebrafish and in vitro based on network analysis
Frontiers in Pharmacology, 2022 Background: Inadequate lymphangiogenesis is closely related to the occurrence of many kinds of diseases, and one of the important treatments is to promote lymphangiogenesis.
Longping Peng +13 more
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