Results 21 to 30 of about 16,311 (176)

Role of Extracellular Vesicles on Cancer Lymphangiogenesis and Lymph Node Metastasis

open access: yesFrontiers in Oncology, 2021
Lymph node metastasis (LNM) of tumors is an established indicator of poor prognosis in patients. Tumor-associated lymphangiogenesis is a key step in LNM and has gained much attention. However, currently, there is no anti-tumor lymphangiogenesis drug used
Linlin Wang, Ling Li, Guiquan Zhu
doaj   +1 more source

Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. [PDF]

open access: yesPLoS ONE, 2011
Lymphangiogenesis is a common phenomenon observed during inflammation and engraftment of transplants, but its precise role in the immune response and underlying mechanisms of regulation remain poorly defined. Here we showed that in response to injury and
Na Yin   +6 more
doaj   +1 more source

Exosomal circ_0026611 contributes to lymphangiogenesis by reducing PROX1 acetylation and ubiquitination in human lymphatic endothelial cells (HLECs)

open access: yesCellular & Molecular Biology Letters, 2023
Background Esophageal squamous carcinoma (ESCC) is a common malignancy that originates in the digestive tract. Lymph node metastasis (LNM) is a complicated process, and tumor lymphangiogenesis has been reported to be associated with the spread of tumor ...
Wenjian Yao   +6 more
doaj   +1 more source

Lymphangiogenesis and carcinoma in the uterine cervix: Joint and hierarchical models for random cluster sizes and continuous outcomes [PDF]

open access: yesAnnals of Applied Statistics 2015, Vol. 9, No. 4, 1932-1949, 2016
Although the lymphatic system is clearly linked to the metastasis of most human carcinomas, the mechanisms by which lymphangiogenesis occurs in response to the presence of carcinoma remain unclear. Hierarchical models are presented to investigate the properties of lymphatic vessel production in 2997 fields taken from 20 individuals with invasive ...
arxiv   +1 more source

Kuoxin Decoction promotes lymphangiogenesis in zebrafish and in vitro based on network analysis

open access: yesFrontiers in Pharmacology, 2022
Background: Inadequate lymphangiogenesis is closely related to the occurrence of many kinds of diseases, and one of the important treatments is to promote lymphangiogenesis.
Longping Peng   +13 more
doaj   +1 more source

Progress in the Mechanism of Lymphangiogenesis and Lymphatic Metastasis 
of Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2021
Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
doaj   +1 more source

Effects of inhibition of lymphangiogenesis by the vascular endothelial growth factor receptor 3 (VEGFR-3) inhibitor, MAZ51 on full thickness wounds in mice

open access: yesVeins and Lymphatics, 2021
We herein used MAZ51 to inhibit lymphangiogenesis and aimed to clarify the effect of inhibition of lymphangiogenesis on wound healing. BALB/c male mice were divided into two groups: the control group which was injected the dimethyl sulfoxide (DMSO), the ...
Kana Takada   +7 more
doaj   +1 more source

Lymphangiogenesis Guidance Mechanisms and Therapeutic Implications in Pathological States of the Cornea

open access: yesCells, 2023
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam   +7 more
doaj   +1 more source

Structure-preserving semi-convex-splitting numerical scheme for a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]

open access: yesarXiv, 2023
A fully discrete semi-convex-splitting finite-element scheme with stabilization for a Cahn-Hilliard cross-diffusion system is analyzed. The system consists of parabolic fourth-order equations for the volume fraction of the fiber phase and solute concentration, modeling pre-patterning of lymphatic vessel morphology.
arxiv  

Effects of adenosine on lymphangiogenesis. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood but promotes tumor spread and metastasis during ...
Bénédicte Lenoir   +6 more
doaj   +1 more source

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