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Role of Extracellular Vesicles on Cancer Lymphangiogenesis and Lymph Node Metastasis
Lymph node metastasis (LNM) of tumors is an established indicator of poor prognosis in patients. Tumor-associated lymphangiogenesis is a key step in LNM and has gained much attention. However, currently, there is no anti-tumor lymphangiogenesis drug used
Linlin Wang, Ling Li, Guiquan Zhu
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Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. [PDF]
Lymphangiogenesis is a common phenomenon observed during inflammation and engraftment of transplants, but its precise role in the immune response and underlying mechanisms of regulation remain poorly defined. Here we showed that in response to injury and
Na Yin+6 more
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Background Esophageal squamous carcinoma (ESCC) is a common malignancy that originates in the digestive tract. Lymph node metastasis (LNM) is a complicated process, and tumor lymphangiogenesis has been reported to be associated with the spread of tumor ...
Wenjian Yao+6 more
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Lymphangiogenesis and carcinoma in the uterine cervix: Joint and hierarchical models for random cluster sizes and continuous outcomes [PDF]
Although the lymphatic system is clearly linked to the metastasis of most human carcinomas, the mechanisms by which lymphangiogenesis occurs in response to the presence of carcinoma remain unclear. Hierarchical models are presented to investigate the properties of lymphatic vessel production in 2997 fields taken from 20 individuals with invasive ...
arxiv +1 more source
Kuoxin Decoction promotes lymphangiogenesis in zebrafish and in vitro based on network analysis
Background: Inadequate lymphangiogenesis is closely related to the occurrence of many kinds of diseases, and one of the important treatments is to promote lymphangiogenesis.
Longping Peng+13 more
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Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
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We herein used MAZ51 to inhibit lymphangiogenesis and aimed to clarify the effect of inhibition of lymphangiogenesis on wound healing. BALB/c male mice were divided into two groups: the control group which was injected the dimethyl sulfoxide (DMSO), the ...
Kana Takada+7 more
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Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam+7 more
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Structure-preserving semi-convex-splitting numerical scheme for a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]
A fully discrete semi-convex-splitting finite-element scheme with stabilization for a Cahn-Hilliard cross-diffusion system is analyzed. The system consists of parabolic fourth-order equations for the volume fraction of the fiber phase and solute concentration, modeling pre-patterning of lymphatic vessel morphology.
arxiv
Effects of adenosine on lymphangiogenesis. [PDF]
BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood but promotes tumor spread and metastasis during ...
Bénédicte Lenoir+6 more
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