Results 31 to 40 of about 38,106 (297)

CD137L-macrophage induce lymphatic endothelial cells autophagy to promote lymphangiogenesis in renal fibrosis

open access: yesInternational Journal on Biological Sciences, 2022
Renal lymphangiogenesis is a new field of international nephrology in recent years and plays an important role in the progression of chronic renal disease.
Haotian Wei   +8 more
semanticscholar   +1 more source

PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor

open access: yesCell Death and Disease, 2021
Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment failure.
Chuanghua Luo   +13 more
doaj   +1 more source

Lymphangiogenesis in renal fibrosis arises from macrophages via VEGF-C/VEGFR3-dependent autophagy and polarization

open access: yesCell Death and Disease, 2021
Inflammation plays a crucial role in the occurrence and development of renal fibrosis, which ultimately results in end-stage renal disease (ESRD). There is new focus on lymphangiogenesis in the field of inflammation.
Ying Zhang   +11 more
semanticscholar   +1 more source

Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas

open access: yesScience Advances, 2021
New approach for immune cell recruitment in therapeutic anticancer vaccines drives antigenically broad and long-lasting immunity. In melanoma, the induction of lymphatic growth (lymphangiogenesis) has long been correlated with metastasis and poor ...
M. Sasso   +7 more
semanticscholar   +1 more source

Promoting inflammatory lymphangiogenesis by vascular endothelial growth factor-C (VEGF-C) aggravated intestinal inflammation in mice with experimental acute colitis [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2016
Angiogenesis and lymphangiogenesis are thought to play a role in the pathogenesis of inflammatory bowel diseases (IBD). However, it is not understood if inflammatory lymphangiogenesis is a pathological consequence or a productive attempt to resolve the ...
X.L. Wang, J. Zhao, L. Qin, M. Qiao
doaj   +3 more sources

Signaling of Prostaglandin E Receptors, EP3 and EP4 Facilitates Wound Healing and Lymphangiogenesis with Enhanced Recruitment of M2 Macrophages in Mice. [PDF]

open access: yesPLoS ONE, 2016
Lymphangiogenesis plays an important role in homeostasis, metabolism, and immunity, and also occurs during wound-healing. Here, we examined the roles of prostaglandin E2 (PGE2) receptor (EP) signaling in enhancement of lymphangiogenesis in wound healing ...
Kanako Hosono   +4 more
doaj   +1 more source

VEGF‐C/VEGFR‐3 axis protects against pressure‐overload induced cardiac dysfunction through regulation of lymphangiogenesis

open access: yesClinical and Translational Medicine, 2021
Prolonged pressure overload triggers cardiac hypertrophy and frequently leads to heart failure (HF). Vascular endothelial growth factor‐C (VEGF‐C) and its receptor VEGFR‐3 are components of the central pathway for lymphatic vessel growth (also known as ...
Qiu-Yue Lin   +4 more
semanticscholar   +1 more source

Lymphangiogenesis and cancer metastasis [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2009
Abstract Anatomy and function of the lymphatic system Tumour‐induced lymphangiogenesis promotes metastasis Tumour‐induced lymph node lymphangiogenesis precedes cancer metastasis to lymph nodes Tumour cell invasion into lymphatic vessels Peri‐ and intra‐tumoral lymphangiogenesis Lymphatic vessel markers and lymphangiogenic growth factors Preventive and ...
Viviane Mumprecht, Michael Detmar
openaire   +3 more sources

Lymphangiogenesis is required for pancreatic islet inflammation and diabetes. [PDF]

open access: yesPLoS ONE, 2011
Lymphangiogenesis is a common phenomenon observed during inflammation and engraftment of transplants, but its precise role in the immune response and underlying mechanisms of regulation remain poorly defined. Here we showed that in response to injury and
Na Yin   +6 more
doaj   +1 more source

Integrins in angiogenesis and lymphangiogenesis [PDF]

open access: greenNature Reviews Cancer, 2008
Blood vessels promote tumour growth, and both blood and lymphatic vessels facilitate tumour metastasis by serving as conduits for the transport of tumour cells to new sites. Angiogenesis and lymphangiogenesis are regulated by integrins, which are members of a family of cell surface receptors whose ligands are extracellular matrix proteins and ...
Christie J. Avraamides   +2 more
openalex   +5 more sources

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