Results 1 to 10 of about 4,821,171 (308)
Signaling in Lymphocyte Activation [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 The fate of T and B lymphocytes, the key cells that direct the adaptive immune response, is regulated by a diverse network of signal transduction pathways. The T- and B-cell antigen receptors are coupled to intracellular tyrosine kinases and adaptor molecules to control the metabolism of inositol phospholipids and calcium release.
D. Cantrell
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Continuous Modeling of T CD4 Lymphocyte Activation and Function [PDF]
Frontiers in Immunology, 2021 T CD4+ cells are central to the adaptive immune response against pathogens. Their activation is induced by the engagement of the T-cell receptor by antigens, and of co-stimulatory receptors by molecules also expressed on antigen presenting cells. Then, a
David Martínez-Méndez +5 more
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Human Plasma-like Medium Improves T Lymphocyte Activation
iScience, 2020 Summary: T lymphocytes are critical for effective immunity, and the ability to study their behavior in vitro can facilitate major insights into their development, function, and fate.
Michael A. Leney-Greene +4 more
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Lactate dehydrogenase-elevating virus induces systemic lymphocyte activation via TLR7-dependent IFNalpha responses by plasmacytoid dendritic cells. [PDF]
PLoS ONE, 2009 BACKGROUND:Lactate dehydrogenase-elevating virus (LDV) is a natural infectious agent of mice. Like several other viruses, LDV causes widespread and very rapid but transient activation of both B cells and T cells in lymphoid tissues and the blood.
Christoph G Ammann +3 more
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Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
Science, 2016 Xiaobo Mao +2 more
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Enteric Glia Regulate Lymphocyte Activation via Autophagy-Mediated MHC-II Expression
Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims Enteric glial cells express type II major histocompatibility complex (MHC-II) molecules in Crohn’s disease and Chagas disease, but it is unclear whether the expressed molecules are functional.
A. Chow +2 more
semanticscholar +1 more source
Biomedical Journal, 2022 T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
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Activation of lymphocytes [PDF]
Journal of Clinical Pathology, 1967 The technique involved in studying the activation of lymphocytes in the resting form, and their recognition as dividing and functional cells was studied, using phase contrast and agar as well as fluid culture. Standardization of technical methods was found to be essential, and the effect of variables was studied.
R J, Pulvertaft, I, Pulvertaft
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FcγRI FG-loop functions as a pH sensitive switch for IgG binding and release
Frontiers in Immunology, 2023 Understanding the molecular mechanism underlying the hierarchic binding between FcγRs and IgG antibodies is critical for therapeutic antibody engineering and FcγR functions.
Jinghua Lu +5 more
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