Results 31 to 40 of about 4,241,016 (384)
Frontiers in Immunology, 2018 Epstein–Barr Virus (EBV) is a gamma-herpes virus that infects 90% of humans without any symptoms in most cases, but has an oncogenic potential, especially in immunocompromised individuals.
Sylvain Latour +5 more
doaj +1 more source
Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility
EMBO Molecular Medicine, 2018 Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter +9 more
doaj +1 more source
Frontiers in Pharmacology, 2020 The polysaccharide of Atractylodes macrocephala Koidz (PAMK) is recognized as an immune enhancer, with anti-cancer, anti-tumour, lymphocyte-activating and lymphocytes proliferation-inducing effects.
Xuelian Xiang +8 more
doaj +1 more source
Increased lymphocyte activation and atherosclerosis in CD47-deficient mice
Scientific Reports, 2019 CD47, also known as integrin-associated protein (IAP), is a transmembrane protein with multiple biological functions including regulation of efferocytosis and leukocyte trafficking.
D. Engelbertsen +12 more
semanticscholar +1 more source
Biomedical Journal, 2022 T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj
T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action [PDF]
, 2004 Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to ...
Caro, I. +7 more
core +1 more source
Lymphocyte‐activation gene‐3, an important immune checkpoint in cancer
Cancer Science, 2016 Immunotherapy has recently become widely used in lung cancer. Many oncologists are focused on cytotoxic T lymphocyte antigen‐4 (CTLA‐4), programmed cell death ligand‐1 (PD‐L1) and programmed cell death‐1 (PD‐1).
Yayi He +7 more
semanticscholar +1 more source
Activated T lymphocytes in uveitis. [PDF]
British Journal of Ophthalmology, 1988 Two colour flow cytometry techniques were used to assess the activation stages of peripheral and intraocular T lymphocytes in uveitis. Increased numbers of T lymphocytes bearing the interleukin-2 (IL-2) receptors were found in intraocular fluids or peripheral blood or both of 35/51 patients with uveitis.
J. Deschênes, S. Kaleta, Devron H. Char
openaire +3 more sources
Frontiers in Immunology, 2017 Available evidence indicates that the CD6 lymphocyte surface receptor is involved in T-cell developmental and activation processes, by facilitating cell-to-cell adhesive contacts with antigen-presenting cells and likely modulating T-cell receptor (TCR ...
Esther Carrasco +10 more
doaj +1 more source
A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation [PDF]
, 2015 Lymphocyte apoptosis is mainly induced by either death receptor-dependent activation of caspase-8 or mitochondria-dependent activation of caspase-9. Mutations in caspase-8 lead to autoimmunity/lymphoproliferation and immunodeficiency. This work describes
Boggio, E +15 more
core +2 more sources