Results 51 to 60 of about 17,417 (215)
A Novel Murine Model of Hemophagocytic Lymphohistiocytosis‐Like Inflammation in ZNFX1 Deficiency
European Journal of Immunology, Volume 56, Issue 2, February 2026.LCMV‐infected Znfx1‐deficient mice develop hemophagocytic lymphohistiocytosis (HLH)‐like immune dysregulation, mirroring key aspects of the immunopathology observed in ZNFX1‐deficient patients. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a severe inflammatory syndrome characterized by persistent activation of lymphocytes and macrophages ...
Diana Tintor +9 more
wiley +1 more source
Pet Rodents and Fatal Lymphocytic Choriomeningitis in Transplant Patients
Emerging Infectious Diseases, 2007 In April 2005, 4 transplant recipients became ill after receiving organs infected with lymphocytic choriomeningitis virus (LCMV); 3 subsequently died. All organs came from a donor who had been exposed to a hamster infected with LCMV.
Brian R. Amman +21 more
doaj +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges
Advanced Science, Volume 13, Issue 5, 27 January 2026.This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li +7 more
wiley +1 more source
Viruses, 2019 Virology has played an essential role in deciphering many immunological phenomena, thus shaping our current understanding of the immune system. Animal models of viral infection and human viral infections were both important tools for immunological ...
Mohamed S. Abdel-Hakeem
doaj +1 more source
Stewardship of Molecular Diagnostics in Transplant Viral Infections
Transplant Infectious Disease, Volume 28, Issue 1, January/February 2026.ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden +3 more
wiley +1 more source
Cell Culture and Electron Microscopy for Identifying Viruses in Diseases of Unknown Cause
Emerging Infectious Diseases, 2013 During outbreaks of infectious diseases or in cases of severely ill patients, it is imperative to identify the causative agent. This report describes several events in which virus isolation and identification by electron microscopy were critical to ...
Cynthia S. Goldsmith +17 more
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.A wide spectrum of cells in the brain can engage in antigen presentation, which activates adaptive immunity in the central nervous system (CNS). Tissue‐resident memory T cells (TRM) develop in adaptive immunity in the CNS and provide long‐term immune surveillance, including the clearance of pathogens and tumor cells.
Luojinyun Wang +8 more
wiley +1 more source
Public Health Challenges, Volume 4, Issue 4, December 2025.GRAPHICAL ABSTRACT Conflict‐driven destruction in Gaza has caused water and sanitation collapse, leading to infestations of rodents and insects, escalating public health risks among displaced populations. ABSTRACT The current study investigates the severe environmental and public health impacts resulting from the ongoing conflict in the Gaza Strip ...
Zuhair Dardona, Samia Boussaa
wiley +1 more source
Lymphocytic choriomeningitis virus meningitis after needlestick injury: a case report
Antimicrobial Resistance and Infection Control, 2019 Background Needlestick accidents while handling of infectious material in research laboratories can lead to life-threatening infections in laboratory personnel.
Sarah Dräger +6 more
doaj +1 more source