Results 101 to 110 of about 34,914 (256)

Cytological Features of Pancreatic Medullary Carcinoma Diagnosed by Endoscopic Ultrasound‐Guided Fine Needle Aspiration

Diagnostic Cytopathology, Volume 54, Issue 2, Page E54-E58, February 2026.
ABSTRACT Pancreatic medullary carcinoma is an extremely rare tumor classified as a histological subtype of pancreatic ductal adenocarcinoma. We report a case of a pancreatic medullary carcinoma and describe its cytological features. A 75‐year‐old woman presented with lower back pain, epigastric discomfort, and a tumor‐like lesion in the pancreatic body.
Urara Okawa, Keishi Mizuguchi, Miyu Okuda, Tatsuya Mori, Hiroko Ikeda   +4 more
wiley   +1 more source

Pathogenic Variants in Mennonites From Southern Brazil: Implications for Preventive Measures in Public Health

Clinical Genetics, Volume 109, Issue 2, Page 266-276, February 2026.
In 325 exomes of South Brazilian Mennonites, we identified 23 pathogenic variants (P) and 27 likely P, with founder effects identified for 96% of P, whose frequencies differed from non‐Finnish Europeans, Amish, and Brazilian populations. ABSTRACT The Mennonite population has a unique history of 500 years of genetic isolation shaped by at least three ...
Luiza Beatriz Mayer de Lima, Eduardo Delabio Auer, Isabela Dall’Oglio Bucco, Valéria Bumiller‐Bini Hoch, Priscila Ianzen dos Santos, Fabiana L. Lopes, Alan Shuldiner, Emilton Lima Júnior, Angelica Beate Winter Boldt   +8 more
wiley   +1 more source

MSH6 germline mutations leading to Lynch syndrome-associated cholangiocarcinoma: a case report

Frontiers in Oncology
Lynch syndrome, a hereditary cancer susceptibility syndrome, arises from pathogenic mutations in mismatch repair genes. This syndrome is strongly linked to colorectal and endometrial cancers, as well as an elevated risk for other cancers such as gastric,
Zheng Zhang, Subo Ma, Shixing Li, Zhengfu Chen, Runda Song, Zhanpeng Wang   +5 more
doaj   +1 more source

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members [PDF]

, 2009
Heikki Järvinen, Laura Renkonen‐Sinisalo, Katja Aktan–Collan, Païvi Peltomäki, Lauri A. Aaltonen, Jukka‐Pekka Mecklin   +5 more
openalex   +1 more source

A Case of Lynch Syndrome-Associated Colorectal Adenocarcinoma in a 19-Year-Old Female Patient [PDF]

, 2023
Aimen Iqbal, Sandra K Rabat, Ravleen Kaur, Muhammad Waqas, Sanya Badar, Faryal Haider, Muneebuddin Syed, Linda Thomas   +7 more
openalex   +1 more source

If treating obesity with GLP‐1‐based therapies protects the heart, could it also prevent cancer or improve cancer outcomes? The case for randomized trials

Diabetes, Obesity and Metabolism, EarlyView.
Anastasios Tentolouris, Ioannis Ntanasis‐Stathopoulos   +1 more
wiley   +1 more source

Blurring the Lines: Co‐Occurrence of MSH6 Variant and MLH1 Constitutional Epimutation in a Young Colorectal Cancer Patient

Clinical Genetics, Volume 109, Issue 2, Page 363-367, February 2026.
We report a unique case of early‐onset colorectal cancer with both a germline MSH6 variant and constitutional mosaic MLH1 epimutation, revealing a possible digenic mechanism underlying Lynch syndrome. This case highlights the diagnostic complexity of mismatch repair deficiency and the value of integrative tumor–germline molecular profiling.
Aasem Abu Shtaya, Yarin Hadid, Ahmad Mahamid, Debora Kidron, Naama Halpern, Adel Shalata, Zohar Levi, Yael Goldberg   +7 more
wiley   +1 more source

The cost-effectiveness of routine testing for Lynch syndrome in newly diagnosed patients with colorectal cancer in the United States: corrected estimates [PDF]

, 2015
Scott D. Grosse, Glenn E. Palomaki, Mercy Mvundura, Heather Hampel   +3 more
openalex   +1 more source

ICSH Recommendations for Monocyte Cell Lineage Morphologic Identification, Nomenclature Harmonization, and Utilization as a Biomarker

International Journal of Laboratory Hematology, Volume 48, Issue 1, Page 12-25, February 2026.
ABSTRACT Monocytes are key components of the Mononuclear Phagocyte System, crucial in immune defense, inflammation, and tissue repair. Accurate identification and classification of monocyte lineage cells are essential for diagnosing both reactive and clonal hematologic disorders.
Gina Zini, Yoon Hwan Chang, Giuseppe d'Onofrio, John Frater, Ulrich Germing, Anna Merino, Olga Pozdnyakova, David Ross, Claudio Romulo Siqueira Filho, Akiyoshi Takami, Erber Wendy   +10 more
wiley   +1 more source

A Knockout for Lynch Syndrome [PDF]

, 2010
C. Richard Boland
openalex   +1 more source