Results 121 to 130 of about 34,914 (256)

Gastrointestinal surveillance and management in Lynch syndrome

, 2023
Jasmijn F. Haanstra
openalex   +2 more sources

Molecular Profile of MSH6-Associated Colorectal Carcinomas Shows Distinct Features From Other Lynch Syndrome–Associated Colorectal Carcinomas [PDF]

, 2023
Noah C. Helderman, A. Lam, Hans Morreau, Arnoud Boot, Tom van Wezel, Maartje Nielsen, Diantha Terlouw, Sanne W. ten Broeke, Mar Rodríguez‐Girondo, Demi van Egmond, Alexandra M. J. Langers, Monique E. van Leerdam, Emily Rayner, Christi J. van Asperen, Liselotte P. van Hest, Hans J.P. Gille, Floor A.M. Duijkers, Anja Wagner, Ellis L. Eikenboom, Tom G.W. Letteboer, Mirjam M. de Jong, Fonnet E. Bleeker, E. Gómez, Manon Suerink, Carli M.J. Tops, Niels de Wind   +25 more
openalex   +1 more source

Mismatch repair genes in Lynch syndrome: a review

São Paulo Medical Journal
Lynch syndrome represents 1-7% of all cases of colorectal cancer and is an autosomal-dominant inherited cancer predisposition syndrome caused by germline mutations in deoxyribonucleic acid (DNA) mismatch repair genes.
Felipe Cavalcanti Carneiro da Silva, Mev Dominguez Valentin, Fábio de Oliveira Ferreira, Dirce Maria Carraro, Benedito Mauro Rossi   +4 more
doaj   +1 more source

Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database

, 2023
Mev Dominguez–Valentin, Saskia Haupt, Toni T. Seppälä, Julian R. Sampson, Lone Sunde, Inge Bernstein, Mark A. Jenkins, Christoph Engel, Stefan Aretz, Maartje Nielsen, Gabriel Capellá, Francesc Balaguer, D. Gareth Evans, John Burn, Elke Holinski‐Feder, Lucio Bertario, Bernardo Bonanni, Annika Lindblom, Zohar Levi, Finlay Macrae, Ingrid Winship, John‐Paul Plazzer, Rolf H. Sijmons, Luigi Laghi, Adriana Della Valle, Karl Heinimann, Tadeusz Dębniak, Robert Fruscio, Francisco Lopez-Koestner, Karin Alvarez-Valenzuela, Lior H. Katz, Ido Laish, E Vainer, Carlos Vaccaro, Dirce Maria Carraro, Kevin Monahan, Elizabeth Half, Áine Stakelum, D. C. Winter, Rory Kennelly, Nathan Gluck, Harsh Sheth, Naim Abu‐Freha, Marc S. Greenblatt, Bernard Rossi, Mábel Bohórquez, Giulia Martina Cavestro, Leonardo S. Lino‐Silva, Karoline Horisberger, Maria Grazia Tibiletti, Ivana do Nascimento, Huw Thomas, Norma Rossi, Leandro Apolinário da Silva, Attila Zaránd, Juan Ruiz‐Bañobre, Vincent Heuveline, Jukka‐Pekka Mecklin, Kirsi Pylvänäinen, Laura Renkonen‐Sinisalo, Anna Lepistö, Païvi Peltomäki, Christina Therkildsen, Mia Gebauer Madsen, Stefan Kobbelgaard Burgdorf, John L. Hopper, Aung Ko Win, Robert W. Haile, Noralane M. Lindor, Steven Gallinger, Loı̈c Le Marchand, Polly A. Newcomb, Jane C. Figueiredo, Daniel D. Buchanan, Stephen N. Thibodeau, Magnus von Knebel Doeberitz, Markus Loeffler, Nils Rahner, Evelin Schröck, Verena Steinke‐Lange, Wolff Schmiegel, Deepak Vangala, Claudia Perne, Robert Hüneburg, Silke Redler, Reinhard Büttner, Jürgen Weitz, Marta Pineda, Núria Dueñas, Joan Brunet, Leticia Moreira, Ariadna Sánchez, Eivind Hovig, Sigve Nakken, Kate Green, Fiona Lalloo, James Hill, Emma J. Crosbie, Miriam Mints, Yael Goldberg   +99 more
openalex   +1 more source

Probiotic Development Strategy Centered on Stability and Regulatory Considerations

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The development of probiotic strains has become a major focus in both academic and industrial research, driven by their health benefits and growing consumer demand. However, functional outcomes demonstrated under laboratory conditions often fail to align with the stability and large‐scale performance required for industrial applications ...
Hye Kim, Md Ariful Haque, Md Abdur Razzak, Min Ji Jang, Sehyeon Song, Seockmo Ku   +5 more
wiley   +1 more source

Exploring endometrial cancer in premenopausal women—A nationwide PremEnCa cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 1, Page 195-206, January 2026.
Almost half of the cohort of EC in women ≤50 has obesity and the prognosis is generally excellent. Non‐endometrioid histology and advanced tumor stage were the strongest negative prognostic factors. Half of the deaths were due to non‐cancer causes, emphasizing the need for a focus on overall health.
Chrysanthos Ioannou, Cecilia Malmsten, Per Ehn, Erik Holmberg, Pernilla Dahm‐Kähler, Karin Stålberg   +5 more
wiley   +1 more source

“Irresponsible Not to Share Such Important Information”: A Narrative of Responsibility That Underpins Familial Disclosure of Genetic Risk in Singapore

Bioethics, Volume 40, Issue 1, Page 85-93, January 2026.
ABSTRACT Patients diagnosed with familial hypercholesterolaemia (FH) are advised to disclose their diagnosis to at‐risk relatives, as early knowledge of genetic risk allows relatives to manage their cholesterol levels. Debates in the bioethical literature regarding familial disclosure of genetic risk tend to revolve around rights: the right of the ...
Serene Ong
wiley   +1 more source

P621: The health economics of Lynch syndrome screening in colorectal cancer: When genetic testing is cost-saving in a middle-income country [PDF]

Pongtawat Lertwilaiwittaya, Natthakan Chitpim, Varalak Srinonprasert, Manop Pithukpakorn, Vitcha Poonyakanok, Pattara Leelahavarong, Suchapa Arayakarnkul, Anna Hurst   +7 more
openalex   +1 more source

Use of multigene‐panel identifies pathogenic variants in several CRC‐predisposing genes in patients previously tested for Lynch Syndrome [PDF]

, 2017
Maren F. Hansen, Jostein Johansen, Anna E. Sylvander, Inga Bjørnevoll, Bente A. Talseth‐Palmer, Liss Anne Solberg Lavik, Alexandre Xavier, Lars Engebretsen, Rodney J. Scott, Finn Drabløs, Wenche Sjursen   +10 more
openalex   +1 more source

The crisis we are not naming: The psychology of capitalism

British Journal of Social Psychology, Volume 65, Issue 1, January 2026.
Abstract Psychology has rendered capitalism invisible, treating individualism as cultural inheritance rather than a response to contemporary economic conditions. Building on my recent theoretical framework (Bettache, Personality and Social Psychology Review, 29, 215, 2024), this article explores how capitalism functions as a missing link in psychology ...
Karim Bettache
wiley   +1 more source