Results 61 to 70 of about 34,914 (256)

Diagnosis of Lynch Syndrome-associated Prostatic Small Cell Neuroendocrine Carcinoma: A Clinical Case Analysis

CT Lilun yu yingyong yanjiu
Lynch syndrome is an autosomal dominant hereditary cancer syndrome characterized by germline mutations in DNA mismatch repair genes. Lynch syndrome-associated small cell neuroendocrine carcinoma of the prostate is an extremely rare extracolonic tumor ...
Heshi LIU, Yong CHEN, Xinran WANG, Xiaofeng QI   +3 more
doaj   +1 more source

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome)

Revista de la Facultad de Medicina, 2016
Lynch syndrome is the most common cause of inherited colorectal cancer, totaling 5 to 8% of all the cases with high susceptibility to this type of cancer and extracolonic cancer.
David Serrano, Clara Eugenia Arteaga
doaj   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

Experiences of parents of children with special needs: Educational services, challenges and recommendations from parents' perspectives

British Journal of Special Education, EarlyView.
Abstract Parents of children with special needs in Nigeria are faced with several challenges. In most cases, decisions are taken without their active involvement, despite them being the primary carers for their children with special needs. This research utilised a qualitative research design with fifteen participants to understand parents' perspectives
Noah Agbo, Sylvia Yeboah Boamah
wiley   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Lynch-Syndrom (HNPCC‑Syndrom)

Der Gynäkologe, 2020
Das Lynch-Syndrom (LS) ist eines der haufigsten erblichen Tumorsyndrome. Bei betroffenen Frauen tritt als erstes Malignom (Sentinelkarzinom) haufig ein Endometrium- und/oder Ovarialkarzinom auf, meistens im jungeren Lebensalter als bei sporadischen Fallen.
Emons, Günter, Aretz, Stefan
openaire   +2 more sources

Correction to: Microsatellite instability in noncolorectal and nonendometrial malignancies in patients with Lynch syndrome [PDF]

, 2023

openalex   +1 more source

Sexual Function, Activity and Distress 24 Months After Surgical Menopause: What Happens After Menopause (WHAM)—A Prospective Controlled Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To determine the effect of surgical menopause (risk‐reducing salpingo‐oophorectomy, RRSO) on sexual function and the modifying effects of HRT. Design Prospective observational study of women undergoing RRSO and age‐matched comparison group who retained their ovaries. Setting High‐risk clinics and general population.
Martha Hickey, Trevor Tejada‐Berges, Susan M. Domchek, Efrosinia O. Krejany, Alison Brand, Peixuan Li, Sabine Braat, Sheryl Kingsberg   +7 more
wiley   +1 more source

Implementing recommendations for routine mismatch repair (MMR) immunohistochemistry (IHC) testing of endometrial cancer and subsequent patient management

BMJ Open Quality
Lynch syndrome is associated with an increased risk of cancer, including endometrial cancer. We audited the introduction of a nurse-led testing and management pathway for Lynch syndrome.
Jo Morrison, Mohamed Shawky, Maria Murrey   +2 more
doaj   +1 more source

324 The complexity of decision-making for risk-reducing surgery in women with lynch syndrome [PDF]

, 2020
Han Cun, Denise Nebgen, K. Lu
openalex   +1 more source