Results 11 to 20 of about 15,218 (253)

Clinical Research on Lysergic Acid Diethylamide (LSD) in Psychiatry and Neuroscience [PDF]

Pharmaceuticals
Lysergic acid diethylamide (LSD) is gaining renewed interest as a potential treatment for anxiety, depression, and alcohol use disorder, with clinical trials reporting significant symptom reductions and long-lasting effects.
Hossein Omidian, Alborz Omidian
doaj   +2 more sources

Lysergic Acid Amide (LSA), an LSD Analog: Systematic Review of Pharmacological Effects, Adverse Outcomes, and Therapeutic Potentials [PDF]

Pharmacy
Objective: To systematically review the scientific literature on lysergic acid amide (LSA), focusing on its physical, neurobiological, and social effects, as well as its potential risks and therapeutic uses.
Paula S. C. C. Castro, Kae Leopoldo, Maria Olivia Pozzolo Pedro, Juliana Takitane, Henrique Silva Bombana, André Brooking Negrão, Jaqueline R. Scholz, João Maurício Castaldelli-Maia   +7 more
doaj   +2 more sources

A New Synthesis of Lysergic Acid [PDF]

Organic Letters, 2003
[reaction: see text] (+/-)-Lysergic acid has been synthesized via an economical 8-step route from 4-bromoindole and isocinchomeronic acid without the need to protect the indole during the synthesis. Initial efforts to form the simpler 3-acylindole derivatives first and then cyclize these were unsuccessful in the cyclization step.
James B, Hendrickson, Jian, Wang
openaire   +4 more sources

Acute effects of lysergic acid diethylamide (LSD) on resting brain function

Swiss Medical Weekly, 2019
Lysergic acid diethylamide (LSD) is a potent hallucinogenic substance that was extensively investigated by psychiatrists during the 1950s and 1960s.
Felix Müller, Stefan Borgwardt
doaj   +2 more sources

The effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity. [PDF]

Neuropsychopharmacology, 2023
Bedford P, Hauke DJ, Wang Z, Roth V, Nagy-Huber M, Holze F, Ley L, Vizeli P, Liechti ME, Borgwardt S, Müller F, Diaconescu AO.   +11 more
europepmc   +3 more sources

Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants. [PDF]

Neuropsychopharmacology, 2023
Ley L, Holze F, Arikci D, Becker AM, Straumann I, Klaiber A, Coviello F, Dierbach S, Thomann J, Duthaler U, Luethi D, Varghese N, Eckert A, Liechti ME.   +13 more
europepmc   +3 more sources

Systems-level analysis of local field potentials reveals differential effects of lysergic acid diethylamide and ketamine on neuronal activity and functional connectivity. [PDF]

Front Neurosci, 2023
Nasretdinov A, Barrientos SA, Brys I, Halje P, Petersson P.   +4 more
europepmc   +3 more sources

Lysergic Acid Diethylamide (LSD) and the Heart: Exploring the Potential Impacts of LSD on Cardiovascular Function. [PDF]

Cureus
Suleria A, Verma S, Arya K, Stoltzfus MT, Gupta I, Singh B, Shaik T.   +6 more
europepmc   +3 more sources

661. A SINGLE DOSE OF LYSERGIC ACID DIETHYLAMIDE (LSD) REDUCES ALCOHOL CONSUMPTION AND REVERTS DOPAMINERGIC (DA) DISFUNCTION IN MALE MICE [PDF]

Int J Neuropsychopharmacol
I Esquivel, Isabella Soliman, F Ruto, Danilo De Gregorio   +3 more
europepmc   +3 more sources

ESTRATÉGIAS PARA A SÍNTESE DO ÁCIDO LISÉRGICO

Química Nova, 2021
STRATEGIES FOR THE SYNTHESIS OF LYSERGIC ACID. (+)-Lysergic acid [(+)-1] is a precursor of several substances with well-established pharmacological properties, including some drugs approved and commercialized around the world. Thus, the importance of (+)-
Tamiris R. C. Silva, Cristiano Raminelli
doaj   +1 more source