Results 31 to 40 of about 4,996,486 (256)

Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide Microdoses in Healthy Participants. [PDF]

open access: yesClin Pharmacol Ther, 2021
“Microdoses” of lysergic acid diethylamide (LSD) are used recreationally to enhance mood and cognition. Increasing interest has also been seen in developing LSD into a medication. Therefore, we performed a pharmacokinetic‐pharmacodynamic study using very
Holze F   +9 more
europepmc   +2 more sources

A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers. [PDF]

open access: yesJ Psychopharmacol, 2021
Background: Lysergic acid diethylamide (LSD) is an ergot alkaloid derivative with psychedelic properties that has been implicated in the management of persistent pain.
Ramaekers JG   +8 more
europepmc   +2 more sources

ESTRATÉGIAS PARA A SÍNTESE DO ÁCIDO LISÉRGICO

open access: yesQuímica Nova, 2021
STRATEGIES FOR THE SYNTHESIS OF LYSERGIC ACID. (+)-Lysergic acid [(+)-1] is a precursor of several substances with well-established pharmacological properties, including some drugs approved and commercialized around the world. Thus, the importance of (+)-
Tamiris R. C. Silva, Cristiano Raminelli
doaj   +1 more source

Cytotoxic, genotoxic, and oxidative stress-related effects of lysergic acid diethylamide (LSD) and phencyclidine (PCP) in the human neuroblastoma SH-SY5Y cell line. [PDF]

open access: diamondArh Hig Rada Toksikol, 2021
Jurič A   +8 more
europepmc   +2 more sources

BEHAVIORAL AND ELECTROPHYSIOLOGICAL EFFECTS OF LYSERGIC ACID DIETHYLAMIDE (LSD) IN A MOUSE MODEL OF ALCOHOL USE DISORDER (AUD) [PDF]

open access: goldInt J Neuropsychopharmacol
Danilo De Gregorio   +3 more
europepmc   +2 more sources

Use of Lysergic Acid Diethylamide by Major Depression Status.

open access: yesJAMA Psychiatry, 2023
Importance Renewed interest in the clinical potential of hallucinogens may lead people with depression to a generally more positive view of the use of lysergic acid diethylamide (LSD).
Walsh CA   +4 more
europepmc   +2 more sources

A New Synthesis of Lysergic Acid [PDF]

open access: yesOrganic Letters, 2003
[reaction: see text] (+/-)-Lysergic acid has been synthesized via an economical 8-step route from 4-bromoindole and isocinchomeronic acid without the need to protect the indole during the synthesis. Initial efforts to form the simpler 3-acylindole derivatives first and then cyclize these were unsuccessful in the cyclization step.
James B. Hendrickson, Jian Wang
openaire   +4 more sources

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