Results 71 to 80 of about 4,996,486 (256)

Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans [PDF]

open access: yes, 2016
Ayahuasca is an Amazonian psychotropic plant tea typically obtained from two plants, Banisteriopsis caapi and Psychotria viridis. It contains the psychedelic 5-HT2A and sigma-1 agonist N,N-dimethyltryptamine (DMT) plus ß-carboline alkaloids with ...
Alonso López, Joan Francesc   +11 more
core   +2 more sources

Hallucinogens: mechanisms and medical complications [PDF]

open access: yes, 2013
Thesis (M.A.)--Boston UniversityHallucinogens are drugs that alter consciousness by distorting primarily auditory and visual perception but they can affect any sensory system. Hallucinogens also affect judgment, orientation, memory, or emotion.
Chan, Ryan Harry Alexander
core   +1 more source

Analytical and Pharmacological Characterization of 1‐(Furan‐2‐Carbonyl)‐LSD (1F‐LSD) and Comparison With 1‐(Thiophene‐2‐Carbonyl)‐LSD (1T‐LSD)

open access: yesDrug Testing and Analysis, EarlyView.
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt   +5 more
wiley   +1 more source

Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems

open access: yesBiomolecules, 2020
Several pharmacological properties are attributed to ergot alkaloids as a result of their antibacterial, antiproliferative, and antioxidant effects.
Iara Baldim   +12 more
doaj   +1 more source

Harnessing psychedelics for treating posttraumatic stress disorder: Does the science support all the hype?

open access: yesJournal of Traumatic Stress, EarlyView.
Abstract This paper is an edited transcript of a plenary panel held at the 2024 Annual Meeting of the International Society for Traumatic Stress Studies (ISTSS) in Boston, Massachusetts, United States. The panel comprised Drs. Mark Creamer (moderator), Richard Bryant (convenor), Amy Lehrner, Barbara O. Rothbaum, Joseph I. Ruzek, and Paula P.
Mark Creamer   +5 more
wiley   +1 more source

Over 30 million psychedelic users in the United States [v1; ref status: indexed, http://f1000r.es/w8]

open access: yesF1000Research, 2013
We estimated lifetime prevalence of psychedelic use (lysergic acid diethylamide (LSD), psilocybin (magic mushrooms), mescaline, and peyote) by age category using data from a 2010 US population survey of 57,873 individuals aged 12 years and older.
Teri S Krebs, Pål-Ørjan Johansen
doaj   +1 more source

Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey

open access: yesFrontiers in Psychiatry, 2020
BackgroundObservational data and preliminary studies suggest serotonin 2A agonist psychedelics may hold potential in treating a variety of substance use disorders (SUDs), including opioid use disorder (OUD).AimsThe study aim was to describe and analyze ...
Albert Garcia-Romeu   +7 more
doaj   +1 more source

Spectra of ergot alkaloids produced by Claviceps purpurea 1029c in solid-state fermentation system : influence of the composition of liquid medium used for impregnating sugar-cane pith bagasse [PDF]

open access: yes, 1993
A total of 16 different combinations of the liquid nutrient medium used for impregnating sugar-cane pith bagasse have been evaluated for the production of total alkaloids by #Claviceps purpurea$ 1029c in a solid-state fermentation system, and for their ...
Lonsane, B.K.   +3 more
core   +1 more source

The Pharmacology of Lysergic Acid Diethylamide: A Review [PDF]

open access: yesCNS Neuroscience & Therapeutics, 2008
Lysergic acid diethylamide (LSD) was synthesized in 1938 and its psychoactive effects discovered in 1943. It was used during the 1950s and 1960s as an experimental drug in psychiatric research for producing so‐called “experimental psychosis” by altering neurotransmitter system and in psychotherapeutic procedures (“psycholytic” and “psychedelic” therapy)
Dirk O. Stichtenoth   +5 more
openaire   +3 more sources

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

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