Results 41 to 50 of about 14,811 (174)

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn, Fabian B. Haas, Benjamin G. Chavez, Bernd H. Dreyer, Erik V. Reiss, Anne Ziplys, Heiko Weichert, Saskia Hiltemann, José M. Ugalde, Andreas J. Meyer, John C. D'Auria, Stefan A. Rensing, Jos H. M. Schippers   +12 more
wiley   +1 more source

Suppressors of lysine codons may be misacylated lysine tRNAs [PDF]

Journal of Bacteriology, 1983
We describe a novel class of missense suppressors that read the codons for lysine at two positions (211 and 234) in the trpA polypeptide of Escherichia coli. The suppressor mutations are highly linked to lysT, a gene for lysine tRNA. The results suggest that the suppressors are misacylated lysine tRNAs that carry glycine or alanine.
E J, Murgola, F T, Pagel
openaire   +2 more sources

Verticillium dahliae CFEM Effector VdCR Stabilises the Susceptibility Factor GhAGP31 to Suppress Host Vascular Immunity and Promote Cotton Verticillium Wilt

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant pathogenic fungi secrete a wide array of effector proteins to manipulate host immunity, including those containing CFEM (Common in Fungal Extracellular Membranes) domains. Here, we identified a CFEM domain‐containing effector VdCR from Verticillium dahliae, the causal agent of cotton Verticillium wilt.
Bo Pu, Haonan Yu, Zheyu Pan, Lisheng Duan, Tao Liu, Haiyuan Li, Jiali Liu, Renfu Zhang, Xiaoping Hu, Jun Qin   +9 more
wiley   +1 more source

Phage lysin to control the overgrowth of normal flora in processed sputum samples for the rapid and sensitive detection of Mycobacterium tuberculosis by luciferase reporter phage assay

BMC Infectious Diseases, 2013
Background Phage lysin, extracted from three bacteriophages was used in place of antibiotics to control the overgrowth of normal flora in processed sputum samples leading to the sensitive detection of Mycobacterium tuberculosis using diagnostic ...
Subramanyam Balaji, Sivaramakrishnan Gomathi, Dusthackeer Azger, Kumar Vanaja   +3 more
doaj   +1 more source

Duplicate abalone egg coat proteins bind sperm lysin similarly, but evolve oppositely, consistent with molecular mimicry at fertilization. [PDF]

PLoS Genetics, 2013
Sperm and egg proteins constitute a remarkable paradigm in evolutionary biology: despite their fundamental role in mediating fertilization (suggesting stasis), some of these molecules are among the most rapidly evolving ones known, and their divergence ...
Jan E Aagaard, Stevan A Springer, Scott D Soelberg, Willie J Swanson   +3 more
doaj   +1 more source

A Bioluminescence-Based Ex Vivo Burn Wound Model for Real-Time Assessment of Novel Phage-Inspired Enzybiotics

Pharmaceutics, 2022
The silent pandemic of antibiotic resistance is thriving, prompting the urgent need for the development of new antibacterial drugs. However, within the preclinical pipeline, in vitro screening conditions can differ significantly from the final in vivo ...
Vincent De Maesschalck, Diana Gutiérrez, Jan Paeshuyse, Yves Briers, Greetje Vande Velde, Rob Lavigne   +5 more
doaj   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Development of a novel chimeric lysin to combine parental phage lysin and cefquinome for preventing sow endometritis after artificial insemination

Veterinary Research
Sow endometritis is usually caused by multiple species of pathogenic bacteria. Numerous isolates from endometritis patients have developed antimicrobial resistance. Thus, novel antibacterial agents and strategies to combat endometritis are needed.
Xin-xin Li, Zi-qiang Hong, Zhi-xuan Xiong, Li-wen Zhang, Shuang Wang, Pan Tao, Pin Chen, Xiang-min Li, Ping Qian   +8 more
doaj   +1 more source

Arthroscopic “Debridement and Implant Retention” With Local Administration of Exebacase (Lysin CF-301) Followed by Suppressive Tedizolid as Salvage Therapy in Elderly Patients for Relapsing Multidrug-Resistant S. epidermidis Prosthetic Knee Infection

Frontiers in Medicine, 2021
Exebacase, a recombinantly produced lysin has recently (i) reported proof-of-concept data from a phase II study in S. aureus bacteremia and (ii) demonstrated antibiofilm activity in vitro against S. epidermidis.
Tristan Ferry, Tristan Ferry, Tristan Ferry, Tristan Ferry, Cécile Batailler, Cécile Batailler, Cécile Batailler, Aubin Souche, Aubin Souche, Aubin Souche, Aubin Souche, Cara Cassino, Christian Chidiac, Christian Chidiac, Christian Chidiac, Thomas Perpoint, Thomas Perpoint, Claire le Corvaisier, Jérôme Josse, Jérôme Josse, Jérôme Josse, Jérôme Josse, Romain Gaillard, Julien Roger, Camille Kolenda, Camille Kolenda, Camille Kolenda, Camille Kolenda, Sébastien Lustig, Sébastien Lustig, Sébastien Lustig, Frédéric Laurent, Frédéric Laurent, Frédéric Laurent, Frédéric Laurent, The Lyon BJI Study Group   +35 more
doaj   +1 more source

Is quinoa‐farming sustainable in marginal environments? Social, economical and environmental aspects

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8315-8328, November 2026.
Abstract Quinoa (Chenopodium quinoa Willd.) is an Andean grain crop introduced as a novel crop to many parts of the world in recent years. Recognized for nutritious seeds and high abiotic stress tolerance, it has been promoted as an element of climate‐resilient agriculture, particularly in marginal environments.
Anna Tabea Mengen, Damir Esenaliev, Jakhongir Babadjanov, Lukas John, Sandra M. Schmöckel, Botir Khaitov   +5 more
wiley   +1 more source