Results 11 to 20 of about 438,961 (309)

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation. [PDF]

PLoS ONE, 2015
Lysine acetylation has been primarily investigated in the context of transcriptional regulation, but a role for acetylation in mediating other cellular responses has emerged.
Bryan D Bryson, Forest M White
doaj   +8 more sources

Protein Lysine Acetylation [PDF]

Cellular and Molecular Gastroenterology and Hepatology, 2021
he factors that contribute to acute pancreatitis Tdevelopment and modulate its severity continue to be described. In addition to acute injury, chronic cell injury and inflammation, such as seen in chronic pancreatitis, increases the risk of developing ...
Fred S. Gorelick, MD
doaj   +4 more sources

Global Analysis of Lysine Acetylation Suggests the Involvement of Protein Acetylation in Diverse Biological Processes in Rice (Oryza sativa) [PDF]

PLoS ONE, 2014
Lysine acetylation is a reversible, dynamic protein modification regulated by lysine acetyltransferases and deacetylases. Recent advances in high-throughput proteomics have greatly contributed to the success of global analysis of lysine acetylation.
Zhaohua Peng, Babi Ramesh Reddy Nallamilli, Bindu Nanduri   +2 more
exaly   +4 more sources

Lysine Acetylation and Deacetylation in Brain Development and Neuropathies

Genomics, Proteomics & Bioinformatics, 2017
Embryonic development is critical for the final functionality and maintenance of the adult brain. Brain development is tightly regulated by intracellular and extracellular signaling.
Alicia Tapias, Zhao-Qi Wang
doaj   +4 more sources

Global Analysis of Lysine Acetylation in Strawberry Leaves [PDF]

Frontiers in Plant Science, 2015
Protein lysine acetylation is a reversible and dynamic post-translational modification. It plays an important role in regulating diverse cellular processes including chromatin dynamic, metabolic pathways and transcription in both prokaryotes and ...
Liang Jin, Xianping Fang, Chengqi Yan
exaly   +5 more sources

Comprehensive analysis of the lysine acetylome in Aeromonas hydrophila reveals cross-talk between lysine acetylation and succinylation in LuxS

Emerging Microbes and Infections, 2019
Lysine acetylation and succinylation are both prevalent protein post-translational modifications (PTMs) in bacteria species, whereas the effect of the cross-talk between both PTMs on bacterial biological function remains largely unknown.
Lina Sun, Zujie Yao, Zhuang Guo, Lishan Zhang, Yuqian Wang, Ranran Mao, Yuexu Lin, Yuying Fu, Xiangmin Lin   +8 more
doaj   +3 more sources

Influence of N^ε-Lysine Acetylation on the Formation of Protein Aggregates and Antibiotic Persistence in E. coli [PDF]

Molecules
Numerous studies indicate that reversible Nε-lysine acetylation in bacteria may play a key role in the regulation of metabolic processes, transcription and translation, biofilm formation, virulence, and drug resistance.
Karolina Stojowska-Swędrzyńska, Dorota Kuczyńska-Wiśnik, Ewa Laskowska   +2 more
doaj   +3 more sources

Lysine Acetylation, Cancer Hallmarks and Emerging Onco-Therapeutic Opportunities

Cancers, 2022
Simple Summary Several histone deacetylase inhibitors have been approved by FDA for cancer treatment. Intensive efforts have been devoted to enhancing its anti-cancer efficacy by combining it with various other agents.
Mei-Lan Hu, Fu-Le He, E. Thompson, K. Ostrikov, Xiaofeng Dai   +4 more
semanticscholar   +2 more sources

Atlas of lysine acetylation in the mouse

bioRxiv
Lysine acetylation has widespread ramifications from genetic regulatory effects to modulation of enzymatic function. With improved acetyl-lysine enrichment technologies and advances in mass spectrometer speed and sensitivity, we present a comprehensive ...
Ross W. Soens, Benton J. Anderson, Noah M. Lancaster, Mukesh Kumar, J. Hanssen, A. Galmozzi, Timothy Grant, K. Overmyer, J. Coon   +8 more
semanticscholar   +3 more sources

Comprehensive Proteomic Analysis of Lysine Acetylation in the Foodborne Pathogen Trichinella spiralis

Frontiers in Microbiology, 2018
Lysine acetylation is a dynamic and highly conserved post-translational modification that plays a critical role in regulating diverse cellular processes. Trichinella spiralis is a foodborne parasite with a considerable socio-economic impact.
Yong Yang, Yong Yang, Mingwei Tong, Xue Bai, Xiaolei Liu, Xuepeng Cai, Xuepeng Cai, Xuenong Luo, Peihao Zhang, Wei Cai, Isabelle Vallée, Yonghua Zhou, Mingyuan Liu   +12 more
doaj   +3 more sources