Results 101 to 110 of about 11,072 (207)

Unfolding and refolding of cytochrome c driven by the interaction with lipid micelles [PDF]

, 2000
Binding of native cyt c to L-PG micelles leads to a partially unfolded conformation of cyt c. This micelle-bound state has no stable tertiary structure, but remains as -helical as native cyt c in solution.
Pinheiro, Teresa J. T., Sanghera, Narinder   +1 more
core   +2 more sources

Lysophospholipid interactions with protein targets [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2008
Bioactive lysophospholipids include lysophosphatidic acid (LPA), sphingosine 1-phosphate (S1P), cyclic-phosphatidic acid (CPA) and alkyl glycerolphosphate (AGP). These lipid mediators stimulate a variety of responses that include cell survival, proliferation, migration, invasion, wound healing, and angiogenesis.
openaire   +2 more sources

Value of Lysophospholipid Metabolites in Prognosis of Major Adverse Cardiac Events in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention: a Prospective Cohort Study [PDF]

Zhongguo quanke yixue
Background Percutaneous coronary intervention (PCI) is the main treatment for acute coronary syndrome (ACS), but some patients may experience recurrent major cardiovascular events (MACE) after the treatment.
SUN Xuechun, DU Zhiyong, YU Huahui, LYU Qianwen, JIAO Xiaolu, WANG Yu, QIN Yanwen
doaj   +1 more source

G-Protein coupled receptor signalling in pluripotent stem cell-derived cardiovascular cells: Implications for disease modelling [PDF]

, 2015
Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths
Dolatshad, NF, Foldes, G, Harding, SE, Hellen, N, Jabbour, R   +4 more
core   +1 more source

Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

Molecular Oncology, 2019
The peritoneal fluid of ovarian carcinoma patients promotes cancer cell invasion and metastatic spread with lysophosphatidic acid (LPA) as a potentially crucial mediator.
Silke Reinartz, Sonja Lieber, Jelena Pesek, Dominique T. Brandt, Alina Asafova, Florian Finkernagel, Bernard Watzer, Wolfgang Andreas Nockher, Andrea Nist, Thorsten Stiewe, Julia M. Jansen, Uwe Wagner, Anne Konzer, Johannes Graumann, Robert Grosse, Thomas Worzfeld, Sabine Müller‐Brüsselbach, Rolf Müller   +17 more
doaj   +1 more source

The riddle of the Sphinx: why sphingosine‐1‐phosphate may help define molecular mechanisms underlying risk stratification for serious COVID‐19 infections

EMBO Molecular Medicine, 2020
The sphingosine‐1‐phosphate (S1P) is a lysophospholipid signaling molecule with important functions in many physiological and pathological conditions, including viral infection.
Hugh Rosen, Michael B A Oldstone
doaj   +1 more source

Lysophosphatidic Acid Induces Migration of Human Lung‐Resident Mesenchymal Stem Cells Through the β‐Catenin Pathway [PDF]

, 2012
Mesenchymal stem cells (MSCs) have been demonstrated to reside in human adult organs. However, mechanisms of migration of these endogenous MSCs within their tissue of origin are not well understood.
Anliker, Badri, Badri, Belperio, Bienz, Bruno, Bullions, Castelino, Cheon, Contos, Fukushima, Haegel, Harris, Hoogduijn, Hoyles, Huelsken, Humphreys, Lai, Lam, Lama, Maeda, Maijenburg, Moolenaar, Nelson, Neth, Novak, Pradere, Pradere, Rivera, Shevtsov, Tager, Tolar, Walker, Yang   +33 more
core   +1 more source

Characterization of human lysophospholipid acyltransferase 3[S]

Journal of Lipid Research, 2009
Esterifying lysophospholipids may serve a variety of functions, including phospholipid remodeling and limiting the abundance of bioactive lipids. Recently, a yeast enzyme, Lpt1p, that esterifies an array of lysophospholipids was identified.
Shilpa Jain, Xiaoling Zhang, Preeti J. Khandelwal, Aleister J. Saunders, Brian S. Cummings, Peter Oelkers   +5 more
doaj   +1 more source

Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]

, 2018
Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang, Comhair, Suzy, Machado, Roberto F., Natarajan, Viswanathan, Singla, Sunit, Sysol, Justin R., Zhao, Shuangping   +6 more
core   +1 more source

Dietary Lysophosphatidylcholine Improves the Uptake of Astaxanthin and Modulates Cholesterol Transport in Pacific White Shrimp Litopenaeus vannamei

Antioxidants
Astaxanthin (AST), functioning as an efficient antioxidant and pigment, is one of the most expensive additives in shrimp feeds. How to improve the uptake efficiency of dietary astaxanthin into farmed shrimp is of significance.
Ziling Song, Yang Liu, Huan Liu, Zhengwei Ye, Qiang Ma, Yuliang Wei, Lindong Xiao, Mengqing Liang, Houguo Xu   +8 more
doaj   +1 more source