Results 31 to 40 of about 10,942 (204)
Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy
Despite the ubiquitous roles of lipids in biology, the detection of lipids has relied on invasive techniques, population measurements, or nonspecific labeling. Such difficulties can be circumvented by a label-free imaging technique known as coherent anti-
Thuc T. Le, Shuhua Yue, Ji-Xin Cheng
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Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually breaks down.
Tamotsu Tsukahara +2 more
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Dietary Supplementation of Lysophospholipids Affects Feed Digestion in Lambs
Five experiments were conducted to examine effects of lysophospholipids (LPL) on live weight gain, nutrient digestibility, ruminal fermentation parameters, serum biochemical parameters and rumen bacterial community profile in fattening lambs. Two dietary
Qin Huo +14 more
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Phospholipase A1 (PLA1) is an enzyme that cleaves an ester bond at the sn-1 position of glycerophospholipids, producing a free fatty acid and a lysophospholipid.
Shun Yaginuma +2 more
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Lysophospholipid receptors: Signalling, pharmacology and regulation by lysophospholipid metabolism
The lysophospholipids, sphingosine-1-phosphate (S1P), lysophosphatidic acid (LPA), sphingosylphosphorylcholine (SPC) and lysophosphatidylcholine (LPC), activate diverse groups of G-protein-coupled receptors that are widely expressed and regulate decisive cellular functions.
Meyer zu Heringdorf, Dagmar +1 more
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Lysophospholipid mediators in the vasculature [PDF]
Acting through cell surface receptors, “extracellular” lysophosphatidic acid (LPA) influences cell growth, differentiation, apoptosis and development in a wide spectrum of settings [1–5]. Within the vasculature, smooth muscle cells [6, 7], endothelial cells [8] and platelets [9, 10] display notable responses to LPA [11, 12], which likely regulate blood
Paul Mueller +3 more
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Sphingosine 1-phosphate (S1P) is an extra- and intracellular mediator that regulates cell growth, survival, migration, and adhesion in many cell types.
Katja Ihlefeld +9 more
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Daily rhythms of glycerophospholipid synthesis in fibroblast cultures involve differential enzyme contributions [PDF]
Circadian clocks regulate the temporal organization of several biochemical processes including lipid metabolism and their disruption leads to severe metabolic disorders. Immortalized cell lines acting as circadian clocks display daily variations in [32P]-
Acosta Rodríguez, Victoria América +7 more
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Lysophospholipids in laboratory medicine
Lysophospholipids (LPLs), such as lysophosphatidic acid (LPA), sphingosine 1-phosphate (S1P), and lysophosphatidylserine (LysoPS), are attracting attention as second-generation lipid mediators. In our laboratory, the functional roles of these lipid mediators and the mechanisms by which the levels of these mediators are regulated in vivo have been ...
YATOMI, Yutaka +5 more
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Attenuating effects of peroxisome proliferators on the concentration of free arachidonic acid by inducing 1-acyl-2-lysophospholipid acyltransferases in the kidney were studied.
Tohru Yamazaki +6 more
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